Ebene Regina Haycroft

Scientist at The Peter Doherty Institute for Infection and Immunity 🦠

[Ebene Regina Haycroft @EbeneRHaycroft]

@AmyWChung @TheDohertyInst @UniMelbMDHS Did you know antibodies are decorated with sugars!

Well, what we did is profile those sugars early in a SIV/TB-infection model and see how those changes correlated with disease progression! This suggests how antibody sugars may serve as a potential biomarker for TB-disease.
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[Ebene Regina Haycroft @EbeneRHaycroft]

Very excited to share our latest paper! 🥳

We started this project right before the pandemic began, and like many things, was put on hold. Now, after 4-years I’m happy to announce the teams work is finally out!

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[Clinical & Translational Immunology @ClinTransImmuno]

Haycroft et al examined humoral response to SIV-𝘔𝘺𝘤𝘰𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘶𝘮 𝘵𝘶𝘣𝘦𝘳𝘤𝘶𝘭𝘰𝘴𝘪𝘴 coinfection using cynomolgus macaque and concluded that antibody glycosylation correlates with TB disease progression.
@ASImmunology @WileyGlobal
https://t.co/JTjBS1mGo0

[Ebene Regina Haycroft @EbeneRHaycroft]

The biggest thanks to @AmyWChung, Shelby O’Connor & all the collaborators in the team that made this work possible! @TheDohertyInst @UniMelbMDHS

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[I Am Dr. Sam 👩‍🔬 @SamanthaKDavis1]

Want to know what I have been up to lately? Well, we are developing a vaccine to save the pigs from the a-pork-alypse (African swine fever virus) 🐷
Watch the video below for more info on ASF 👇

[Amy Chung @AmyWChung]

Great work by @EbeneRHaycroft that demonstrates how antibody glycosylation early in SIV-TB infection is a biomarker for TB disease progression @TheDohertyInst @UniMelbMDHS

[I Am Dr. Sam 👩‍🔬 @SamanthaKDavis1]

Check out this great work by @EbeneRHaycroft and co. looking at antibody glycosylation in the humoral response to SIV-TB coinfection in 🐒👇

[Sophie Valk @svalko3]

We are recruiting! Looking for an excellent immunologist to join my Unimelb lab as a research officer/post doc on flu and COVID projects https://t.co/sJOVfONa5x

[Kevin John 🧪🧩 @Kev_in_Science]

How do #mucosal antibodies respond after #vaccination or #covid breakthrough infection? 🤔

Do previous exposures shape future #humoral responses?

Our work is finally out as twin publications in @JCI_insight and @ImmunolCellBiol

Short🧵to follow 😉

[Doherty Institute @TheDohertyInst]

New research shows mucosal surfaces in eyes, nose, mouth and throat are crucial to the first line of defence against upper respiratory infections, like #COVID19.
Published in @JCI_insight @ImmunolCellBiol
https://t.co/pdarGnNpwk
@UniMelbMDHS @TheRMH @Kev_in_Science

[Nigel Curtis @nigeltwitt]

BCG vaccine’s off-target effect on herpes simplex virus.

Results from the international 🇦🇺🇳🇱🇬🇧🇪🇸🇧🇷 #BRACEtrial published today show a beneficial effect of BCG on cold sore recurrence.

https://t.co/Cu2vw3dhoS

#BCG #vaccine #RCT #HSV #IDTwitter #WeAreID @eClinicalMed

[The Viral and Vaccine Immunology Lab @viralvaxlab]

Great job, Thu and Lara!

[Amy Chung @AmyWChung]

Congratulations to @SamanthaKDavis1 for her SARS-CoV2 IgA paper being awarded the 2022 CTI @ClinTransImmuno Publication of the year! Thanks to many collaborators including @tham_lab @viralvaxlab @Kev_in_Science @EbeneRHaycroft @TheDohertyInst

[Wai-Hong Tham @tham_lab]

Please RT!

Looking for a lovely #StructuralBiologist to join our lab ⁦⁦@ourANU⁩ ⁦

Fascinated by infectious diseases, nanobodies and structures, please apply! 🦙 🦙 ⁦Closing date October 1st

Postdoctoral Fellow (Tham) - Canberra / ACT https://t.co/I5to1wVq5L

[Ebene Regina Haycroft @EbeneRHaycroft]

@SamanthaKDavis1 @AmyWChung @ProfStephenKent Amazing stuff, congratulations officially doctor Sam!! Woohoo 🥳🥳👏

[Amy Chung @AmyWChung]

Great study by @EbeneRHaycroft @SamanthaKDavis1 exploring how different mutations in SARS-CoV2 RBD influence ACE-2 binding and escape antibody functions. Great explanation of study below @Kev_in_Science @viralvaxlab @tham_lab

[Ebene Regina Haycroft @EbeneRHaycroft]

Very thankful to our collaborators and everyone in the team who really made this possible! 👏 @SamanthaKDavis1 @AmyWChung @Kev_in_Science @ProfStephenKent @viralvaxlab @TheDohertyInst

Full paper link
https://t.co/fCQbMzLSUU

[Ebene Regina Haycroft @EbeneRHaycroft]

🥳 So happy to share my first, first-coauthored paper is finally out! 🥳

What did we do! Well, we looked at 1) #antibody immunity to #SARSCoV2 variants after #vaccination and 2) natural ACE2 polymorphism on affinity to #RBD! A nice summary of key take homes linked below 🦠 1/2

[I Am Dr. Sam 👩‍🔬 @SamanthaKDavis1]

Another piece of work from my phd and from @EbeneRHaycroft masters thesis is finally out! Read it here 👇 key points are broken down in this 🧵 #COVID19 #phdlife #Researchpaper #Antibodies https://t.co/pJrVrSjrPU

[Wen Shi Lee @WenShiLee]

Check out the AI generated summary of our latest study below examining the breadth and durability of the humoral response following Omicron breakthrough infection. 👇

[I Am Dr. Sam 👩‍🔬 @SamanthaKDavis1]

Another piece of work from my phd and from @EbeneRHaycroft masters thesis is finally out! Read it here 👇 key points are broken down in this 🧵 #COVID19 #phdlife #Researchpaper #Antibodies https://t.co/pJrVrSjrPU

[Ruth Amy Purcell @RuthAmyPurcell]

🧵1/n: Can rational induction of antibodies with non-neutralising functions contribute to improved vaccine effectiveness in vulnerable populations? 💉👴🤰

https://t.co/4PfK9ptMdO