Edy Kim

@BrighamWomens @HarvardMed Physician-Scientist. Translational wet/dry lab on the immunology of pulm fibrosis & cardiac arrest. Immigrant

[Edy Kim @EdyKim5]

My reflections on how COVID put the "physician" into phys-scientist. Started my lab then left turn into open-access COVID clinical guidelines. For all of us, a formative time, but hard to say what form...
https://t.co/7lonlnYqRi

[David Leaf @DavidLeaf9]

Huge thanks to @waikarss, @EdyKim5, and @NIDDKgov, without whom this would not have been possible.

[Brigham and Women’s Research @BrighamResearch]

In a new study published in @ScienceTM, researchers from @BrighamAnes @MGHanesthesia and colleagues found new insights into preventing brain injury after cardiac arrest.

Read more: https://t.co/Cx857VhwsS @EdyKim5 @FumitoIchinose https://t.co/uHLdSSOW4z

[Waggoner Lab @LabWaggoner]

Diverse natural killer T cells regulate innate immunity to improve neurological outcomes and survival after cardiac arrest @ScienceTM @EdyKim5
https://t.co/S94cWyhQs6

[Edy Kim @EdyKim5]

Moving to https://t.co/RexTwOGxZL

[Jeffrey Sparks MD MMSc @jeffsparks]

Our review paper led by Alene Saavedra, outlining several nuances that emerged for RA-ILD treatment in the recent ACR/CHEST guideline - in particular AZA and MMF

We also review all trial evidence - only 3 RCTs (n=217 total!) have enrolled RA-ILD pts!

https://t.co/giRbviAzM1

[Jeffrey Sparks MD MMSc @jeffsparks]

Our latest study investigating risk factors for RA-ILD subtypes, led by Dr Gregory McDermott

We systematically identified/subtyped all RA-ILD cases and RA-noILD controls in the @BrighamWomens RA Sequential Study and @MassGenBrigham Biobank (n=3328)

https://t.co/EIlS2609wJ

[Jie Sun @Jie_Immunology]

Our latest one is out @Nature ! We found an aberrant immune epithelial progenitor niche drives post viral lung inflammation and fibrosis #LongCovid. We also pointed out potential therapeutics. https://t.co/SjWkri204x Shout-out to @hnarasim23 and @wqian1016 @PeterChenMD @zangcz

[Jeffrey Sparks MD MMSc @jeffsparks]

High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus - published now in @NatureComms @BrighamResearch

https://t.co/i74LA5PrZV

[Sanjay Mukhopadhyay @smlungpathguy]

1.
Introducing a new thread: super basic lung pathology for PGY1s, with arrows. If you are a PGY1, leave a comment and I will tag you in a future post.

A hamartoma is a disorganized mix of overgrown normal tissues (in their normal location) that creates a mass. Good news: they are benign!

#pathology #pulmpath #tweetorial #pathtweetorial #sblppgy1

[Edy Kim @EdyKim5]

@DrAnneCarpenter We ended up with Sciwheel--google doc and Word doc integration worked better than Zotero for us. Very easy to share sciwheel reference libraries by project.

[Arthur Liesz @ArthurLiesz]

Finally out today! Very proud of this story:

Innate immune memory after Stroke drives remote organ pathology

This study was led by superstar-postdoc @SimatsAlba and X-less Sijia Zhang. @CellCellPress

https://t.co/0pvrxibv6P

[Sanju Sinha @Sanjusinha7]

Have you wondered how Yamanaka found the 4-gene combination to transform somatic cells to stem cells? The # of possibilities are greater than - 20,000^4.

I did this yesterday & read the original paper.

What a journey & pure joy it was! Here’s how he did it. ⌛️

[Edy Kim @EdyKim5]

Collab led by Mari Kamiya (Kim lab), Hogaboam lab, Beth Moore lab, @leticiakawano, Joyce Lee (CU), @FanZhang_Jessie, @jeffsparks, Chip Merriam, co-senior @wm_oldham also of @BWHPulmCCM @BrighamResearch. 7/7

[Edy Kim @EdyKim5]

Our review of immune axes in lung fibrosis @CellCellPress is for the immunologist or cell biologist without a clinical background but reflects our lab's physician-scientist approach. 1/7.

[Edy Kim @EdyKim5]

In conclusion we echo the call of many others for translational insight into the natural history of lung fibrosis: earliest stages, acute exacerbations and integration of genomics with immunophenotyping (and mechanism!). 6/7

[Sasha Prisco, MD, PhD @SashaPrisco]

I highly recommend this leadership & management training program for postdocs & junior faculty!