Will Oldham

Scientist, physician, husband, father of daughters. I study and treat pulmonary hypertension.

@[email protected]

[Rutter Lab @RutterLab]

Two for Thursday: We want to highlight another fantastic collaboration, this time with William Oldham's lab at Brown University and our @N8Krah, demonstrating that MCT4 is a druggable target in pulmonary fibrosis. Check it out here: https://t.co/W5a3hERl30 @UofUHematology @huntsmancancer

Congrats to everyone involved!

[The Pulmonary Vascular Research Institute @PVRI]

Today marks the start of Brad Maron’s two-year term as PVRI President.

As Brad begins his presidency at this milestone moment for our community, his focus over the next two years will centre on:

▪️ Supporting career development across all stages
▪️ Strengthening equity and inclusion across global PH care
▪️ Expanding multidisciplinary collaboration, including AI, data science, and emerging research methods
▪️ Ensuring sustainable growth and transparency, while protecting access for early-career and global members
▪️ Addressing emerging global challenges shaping the future of PH

We’re grateful for Brad’s leadership and look forward to working together to advance research, care, and collaboration for our global PH community.

#PVRI2026

[Navneet Singh, MD, ScM @navneetsinghmd]

Such well deserved recognitions all around! Delighted to see @BrownPVD’s @wm_oldham recognized along with Katarina Zeder for their invaluable contributions to making @PVRI a place where we all feel welcome and are excited to be every year!

[The Pulmonary Vascular Research Institute @PVRI]

Last night was about celebration and recognition ✨🏆️

The PVRI 2026 Gala Dinner honoured outstanding contributions across PH research, mentorship, and service — a powerful reminder of how far we’ve come together as a community.

Congratulations to our 2026 award recipients:
▪️Stephen Archer — PVRI Lifetime Achievement Award
▪️Daniel Colon Hidalgo — Butrous Foundation Young Investigator Award
▪️Sebastien Bonnet & Steeve Provencher — PVRI Achievement Award
▪️Gabor Kovacs — PVRI Achievement Award
▪️Katarina Zeder — PVRI Special Recognition Award
▪️Will Oldham — PVRI Special Recognition Award
▪️Abdullah Aldalaan — PVRI Special Recognition Award
▪️Sylvia Nikkho — Certificate of Recognition

Go raibh míle maith agaibh to all our awardees — and to everyone who makes the global PH community so special 👏

[Navneet Singh, MD, ScM @navneetsinghmd]

#PVRI2026 was incredible! Got to catch up with friends & colleagues, hear exciting science, share our own (using PAEC biopsies & systems pharmacology for precision PAH care) and applaud @BrownPVD colleagues @wm_oldham & Dr. Klinger who were recognized for their own stellar work!

[Will Flanigan @WillRFlanigan]

Super excited to share that my first first-author story is live on BioRxiv! Huge thank you to @ishahjain, Ken Nakamura, + team at @GladstoneInst, @arcinstitute, @UCSF and beyond for their immense efforts on this project. 🧵
https://t.co/hObtT1PpVU

[Raghu Chivukula, MD PhD 🫁🧬🧠 @chivukula_raghu]

Why do some genetic mutations devastate specific tissues while sparing others?

We explore this question in GGC repeat disorders, revealing a mechanism linking protein aggregation to tRNA splicing failure in the brain.

🧵 on our new paper in Science:
🔗 https://t.co/a9rB53kRoS

[Andrew J. Bryant @ajbryantlab]

STING and PH? Check it out!

[Andrew J. Bryant @ajbryantlab]

Ever wonder how smooth muscle and inflammatory cells act through a common mediator in causing pulmonary hypertension? STING may be the answer.

JCI Insight - Opposing roles for myeloid and smooth muscle cell STING in pulmonary hypertension https://t.co/KGy9KGBLpt

[Navneet Singh, MD, ScM @navneetsinghmd]

Yesterday I was so thrilled to support my first mentee - the talented Talia Volpicelli, an MS-1 in the @BrownMedicine Basic and Translational Science Program. She presented our work on MYDGF at the DOM Research Symposium. I’m so excited to see all the great work she produces!

[AJP-Lung Cellular and Molecular Physiology @AJPLung]

Editorial Focus by @navneetsinghmd and @wm_oldham: Targeting type-2 inflammation in pulmonary hypertension: lessons from a novel model
https://t.co/MV83mWk9ni. Read the original article at https://t.co/Ztu3eMBNOm.

[Giulia Menichetti @menicgiulia]

Incredibly honored to see our work featured in the New England Journal of Medicine. Grateful to an outstanding team and collaborators who made this possible. A milestone we’ll never forget. #NEJM @MGBResearchNews @harvardmed @harvard_data @NUnetsi

[Naftali Kaminski @KaminskiMed]

Finally! The Pulmonary Fibrosis Drug Connectome is on #IPFCellAtlas!! If you want to know if a drug is antifibrotic, which cells it targets, or what drugs target a gene , in what cells - go to https://t.co/3acmOQ2RiC click on the Connectome tab. Enjoy!!
#DataSharing
#CurePF4All

[Will Oldham @wm_oldham]

@chansteve73 @BrownPVD Thanks, Steve, that means a lot.

[Will Oldham @wm_oldham]

Excited to announce that, In 26 days, I will be joining Brown University Health! Excited for new colleagues, new opportunities, and renewed energy to advance our work toward a cure for pulmonary fibrosis! @BrownPVD

[Will Oldham @wm_oldham]

@James_West_PhD @BrownPVD @JKropski That is true! Has been interesting to see that fibrosis has grown up from cell/dev bio like PVD has grown up from biochem/metabolism background. Many opportunities for x-pollination. I'll see you in SF!

[Will Oldham @wm_oldham]

@James_West_PhD @BrownPVD Would love to catch up, but my knowledge is admittedly much more limited than your local expert @JKropski ! Heading to ATS?

[Will Oldham @wm_oldham]

Beautiful work! Congratulations! #cureIPF

[Annika Vannan @AnnikaVannan]

It’s my pleasure to announce our recent work published in Nature Genetics: “Spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis” 1/14 https://t.co/2V9nhWeXjI

[The Pulmonary Vascular Research Institute @PVRI]

Hot off the printing press!! #pvri2025 delegate bags are ready. With only 2 weeks to go, we can’t wait to see you all in Rio soon! #pulmonaryhypertension