Elsayed Balbaa

5th y Med student | Clinical research | Biostatistics | Cardiology | Electrophysiology | #EPeeps

[Elsayed Balbaa @Elsayed_balba3]

🎓 REACH: The Research-to-Publication Workshop.

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[Abdalhakim Shubietah @hakeemshubietah]

In our meta-analysis in Cardiovascular Intervention and Therapeutics, we found that among patients with ACS undergoing PCI, stopping aspirin at 3 months ranked highest among all strategies, with no increase in ischemic events.

https://t.co/DQVcS78GbU

@Elsayed_balba3 @M0Elgendy

#CardioTwitter #InterventionalCardiology #PCI #ACS

[Elsayed Balbaa @Elsayed_balba3]

@FCademartiri Congratulations on this important review.
If we have to identify the plaque (we do not know whether there is a plaque), then the question is, "in which diseases?"

[Elsayed Balbaa @Elsayed_balba3]

#CSP outperformed #RVP in #HFpEF_HFmrEF patients at a procedural efficiency cost.
Read the article 👇
#EPeeps #CardioX #Research #HFpEF #CSP #RVP

[Abdalhakim Shubietah @hakeemshubietah]

Our meta-analysis suggests that, in patients with preserved/mildly reduced EF and high anticipated ventricular pacing burden, CSP better preserves LV function than RV pacing, reducing PICM and HFH with shorter paced QRS. https://t.co/4OoXR7NtY8
@Teebi_MD @Elsayed_balba3
#Epeeps

[Elsayed Balbaa @Elsayed_balba3]

@drjohnm They have a clear unit of analysis error, see the plot below, pooling the same control 3 times in the same meta overestimates the effect. My question is, if observational studies, from you opinion, are of no value, should we no longer conduct them?

[Elsayed Balbaa @Elsayed_balba3]

Full article:

https://t.co/ANeEoDSxGJ

[Elsayed Balbaa @Elsayed_balba3]

A new EP piece.
🫀 New meta-analysis just dropped in @CJCardiology :

CSP vs RVP in preserved/mildly reduced EF, 15 RCTs, 1,466 pts.

Key findings:
⬇️66% pacing-induced cardiomyopathy (RR 0.34)
⬇️ 66% HF hospitalization (RR 0.34)
⬆️ LVEF by ~3%
⬇️QRS by 30ms

BUT:
⚠️⬆️ +32 min procedure time
⚠️⬇️ Lower implant success (93.6% vs 99.5%)
⚠️⬆️ Higher radiation dose
⛔️No mortality difference.

Bottom line: CSP is a physiologic pacing strategy that protects the LV, but comes at a procedural cost. Worth it when a high RV burden is expected.
@hakeemshubietah, @mohamadsaad_R, @AmeerAwashra, @QasemWsalah, @M0Elgendy, @emara991, @ElbataaMD, @MRuzieh, @DrMarwanRefaat @Teebi_MD

#EPeeps #Cardiology #CSP #Pacing #HFpEF #PhysiologicPacing #LBBAP

[Elsayed Balbaa @Elsayed_balba3]

🧵 A thought that keeps me up at night:

We anticoagulate AF patients to prevent stroke — but do we ever pause to ask: how many strokes are actually caused by AF?

Evidence says ~20–25% of ischemic strokes are attributed to AF.
(NIH/PMC; ESC; NEJM ELAN Trial 2023)

That means 75–80% of strokes happen for OTHER reasons, yet AF gets much of our preventive focus.

And here's the kicker: ~51% of AF patients eligible for anticoagulation who suffered a stroke weren't even on appropriate therapy beforehand.

So are we treating the rhythm… or preventing the real culprit?

The gap between guideline adherence and real-world practice is where strokes happen. 🔍
#Cardiology #Neurology #AtrialFibrillation #StrokePrevention #MedTwitter

[Elsayed Balbaa @Elsayed_balba3]

@Elshimyy7 @3bdo_7amdi والله ما حصل 😂😂😂

[Gregg W. Stone MD @GreggWStone]

Complete revasc (CR) in pts with non-shock STEMI and multivessel ds. reduces MACE. But is the best timing for non-culprit lsn PCI immediate (during primary PCI) or staged? Our new meta-analysis publ in Circ CV Interv suggests immediate CR may increase mortality, same as in shock.

[Elsayed Balbaa @Elsayed_balba3]

@Elshimyy7 الحاجة لو ملهاش قيمة هيكون عليها طلب ليه؟

[Elsayed Balbaa @Elsayed_balba3]

This makes me sad.

[Agingdoc🩺Dr David Barzilai🔔MD PhD MS MBA DipABLM @agingdoc1]

Sleep timing irregularity in midlife: association with incident major adverse cardiac events and cardiovascular disease mortality over a 10-year follow-up

🫀Individuals with irregular bedtimes had a 2-fold higher risk of MACEs compared to those with regular bedtimes

Irregular sleep midpoints? Also a 2-fold higher risk

https://t.co/1HzYQdywMb

[Elsayed Balbaa @Elsayed_balba3]

@Elshimyy7 انهى غريزة؟ أصل تفرق

[Elsayed Balbaa @Elsayed_balba3]

@MoazElsayed2023 ابعت عنوان البحث 😅😅

[Elsayed Balbaa @Elsayed_balba3]

The unanswered question up to now is, what is the effect of CAC score guided preventive therapies on clinical outcomes?
Is there any survival benefit?

[J P Fanton @HealthyFellow]

Impact of coronary artery calcium scores on cardiovascular risk and preventive therapies: A systematic review and meta-analysis

⁦@reverohealth⁩ ⁦@shashiiyengar⁩ ⁦@Mangan150⁩ https://t.co/p7R1CUaw5i

[Elsayed Balbaa @Elsayed_balba3]

Off the press!
Read our recent paper published in the @SVINJournal, one of the @American_Heart Association journals:

#Intensive Versus Standard Systolic #Blood_Pressure Targets Following Successful #Endovascular_Thrombectomy for #Acute_Ischemic_Stroke: A Systematic Review with Frequentist and #Bayesian Meta-Analysis

Our findings suggest that intensive SBP lowering (SBP target <180 mm Hg) after successful #thrombectomy may worsen #functional outcomes without a clear safety benefit, supporting a standard #guideline_base approach recommended by @American_Heart/@American_Stroke latest guidelines.
Led by @A_Ibrahim_29 and in collaboration with @mothanamanasrah, @ElBenawiH, @giuseppe_ando, and other great team members.

Full article: 👇
https://t.co/I4tKRmwEX2
@ASORUSA @ACCinTouch @HeartNews @AmHeartAdvocacy

#Stroke #Neurology #Thrombectomy #MetaAnalysis #ClinicalResearch #CardioX #MedTwitter #AHA

[Helen Devine @helenldevine]

On that note: The lab is hiring a postgrad researcher to work with both Dr. Ferguson and Dr. Jennifer Richeson starting this summer.

Details below... Come join a new lab with me🤭🤝

[David Gomez @acute_care_doc]

We welcome applications for our post-doctoral fellowship in trauma research

Fully funded, 1 +/- 1 year duration, focus on healthcare resiliency

Expertise in large database analyses and R required

https://t.co/9LYYieSYOp

[Elsayed Balbaa @Elsayed_balba3]

@DrJaidaa @hi_there1978 أتفق

[Elsayed Balbaa @Elsayed_balba3]

@DrJaidaa @hi_there1978 حبيت اوضح الربط بينهم وبين الأدوية النفسية لا أكثر ولا أقل 🫡

[Elsayed Balbaa @Elsayed_balba3]

@DrJaidaa @hi_there1978 أنا متفق مع حضرتك يا دكتور، أنا مجرد شاركت المعلومة فقط 😅. أكيد مش متفق مع محتوى للتويتة يعنى 😅