"oocytes of the marine ascidian Phallusia mammillata treated with the drug BI-D1870 spontaneously form cytoplasmic MT asters, or cytasters"
"there is an intrinsic mechanical pattern-forming module"
https://t.co/5JvhA7JtzW
"We performed single-cell transcriptomics to define embryonic hypothalamic microglia heterogeneity and identified four microglial subsets, including a subpopulation adjacent to NSCs that was responsive to gestational cold stress."
https://t.co/2Mg7H4L8lx
"we investigate the role of architectural constraints on evolution of B3 DNA binding domains that regulate plant embryogenesis."
https://t.co/Fqw3JRiDm0
"we mapped the vertebrate developmental landscape of A-to-I RNA editing, and generated the first comprehensive atlas of editing sites in zebrafish."
https://t.co/rt27GeWUp9
"Pyruvate dehydrogenase kinases (PDK1-4) inhibit the TCA cycle by phosphorylating pyruvate dehydrogenase complex (PDC)."
"PDK family is dispensable for murine embryonic development and that BCKDK serves as a compensatory mechanism by inactivating PDC."
https://t.co/scC7PPailZ
"we develop a single-cell TE processing pipeline, scTE, and report the expression of TEs in single cells in a range of biological contexts"
https://t.co/DHZXd0zGrp
"Using unbiased global sequencing and directed genetic approaches focused on early mammalian development, we find that fetal liver macrophage exhibit a unique expression signature that differentiates them from erythroid and adult macrophage cells"
https://t.co/kSqUJuPflI
"we used the electrolyte indicators CoroNa Green AM and ION Potassium Green-2 AM to directly visualise intracellular concentrations of Na+ and K+, respectively, at each embryonic developmental stage in mouse embryos"
https://t.co/22tclAjKdp
A sperm fuses with an egg to form a zygote. After fertilization, the maternal and paternal chromosomes need to migrate and meet in middle of the zygote.
Our latest work in @NatureComms reveals how this is achieved in mouse zygotes. (1/5)
🔗https://t.co/00rvZEKBva @mpi_bpc
"Embryogenesis and blastogenesis have different morphological and molecular programs"
"we combine transcriptomics and microscopy to build an atlas of the molecular and morphological signatures at each developmental stage for both pathways"
#tunicate
https://t.co/eJ5Y87O2nE
Excited to share our paper describing how the DUB OTUD5 regulates embryogenesis and when misregulated results in a developmental disease. Thank you to all of our collaborators, in particular the Kastner and Rocha labs at NIH! @Nuclear_Rocha https://t.co/QWPoQtzZ2F
"We characterized two brain-specific L1 insertions in neurons and glia from a donor with schizophrenia"
"retrotransposition occurred during early embryogenesis"
#retrotransposon
https://t.co/rZVRF6AFPf
"PIR-1 dephosphorylates ppp-RNAs made by cellular RNA-dependent RNA polymerases (RdRPs) and is required for the maturation of 26G-RNAs, Dicer-dependent small RNAs that regulate thousands of genes during spermatogenesis and embryogenesis."
https://t.co/kIApDoWN1O
Microfluidic model (trapezoid supporting posts👍+Geltrex for cell docking) of early post-implantation human embryogenesis (epiblast lumenogenesis, symmetry breaking, gastrulation) using human #PluripotencyStemCell
Dr. Jianping Fu group Nat Protoc 2021
https://t.co/VcLxx9xGGd