Epigenome Technologies Inc.

Unlocking epigenetic activities with single-cell multi-omics technologies in Epigenome Technologies

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update – Decoding the regulatory programs governing glioblastoma plasticity https://t.co/4T6NyEiMmt

@bayraktar_lab, @OliverStegle, and @MoritzMall in @Nature

#Epigenetics #Glioblastoma #SingleCell #Multiomics #Cancer
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https://t.co/WmSYDGXnzb

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update – The AMPK-ALDH7A1 axis drives metabolic reprogramming and anti-tumor immunity in hepatocellular carcinoma via KDM5C inhibition https://t.co/LGiPncbpoK

#Epigenetics #Chromatin #Metabolism #Cancer #KDM5C
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https://t.co/WmSYDGWPJD

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update – Longitudinal single-cell profiling of breast tumors highlights immune and epigenetic mechanisms associated with sensitivity to aromatase inhibitors https://t.co/kJt4WfsK4i

#Epigenetics #SingleCell #Cancer
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Empower your research; https://t.co/WmSYDGXnzb

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - P-TEFb regulates nucleosome positioning at promoters https://t.co/PYNcwBAmzr

Chengqi Lin and Zhuojuan Luo (Southeast University, Nanjing) in Mol Cell

#Epigenetic #Nucleosome #PTEFb
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Discover the breakthrough at https://t.co/WmSYDGWPJD

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - A TORC1-regulated H3K4me reader preserves promoter chromatin stability, and its degradation promotes meiotic remodeling https://t.co/x1nH30tqdx

#Epigenetics #Chromatin #H3K4me #TORC1
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Gain deeper insights into gene regulation; https://t.co/WmSYDGXnzb

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - The chromatin context differently impacts prime editors and base editors and controls the fidelity and purity of base editing https://t.co/EDD69LITfl

@mafvg_mafvg (Leiden University) in @MolecularCell

#Epigenetics #Chromatin
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https://t.co/WmSYDGXnzb

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - Hematopoietic loss of KDM6A impairs cardiac recovery in heart failure via epigenetic reprogramming of myeloid cells https://t.co/3BU19402sQ

Emmanouil Solomonidis & Sebastian Cremer (Goethe University Frankfurt) in @NatureCVR

#Epigenetics #Chromatin #KDM6A

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - Reconstructing the emergence of the human chorion via Hippo-mediated trophoblast induction https://t.co/4pebjA3mMr

Miaoci Zhang and Mijo Simunovic (@Columbia) in @NatureCellBio

#Epigenetics #Trophoblast #DNam #Chorion

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - A framework for genome-wide characterization of DNA methylation and variant effect prediction https://t.co/IxFVC9lpuQ

Weiguang Mao/Kathleen Chen & @OlgaTroyanskaya (@PrincetonPPH) in @NatureGenet

#Epigenetics #DNAm
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https://t.co/WmSYDGXnzb

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetic Reviews - The genomic and epigenomic evolution of colorectal cancer https://t.co/fOS7FMMCDV

@trevoragraham (@ICR_London) and @AndreaSottoriva (@humantechnopole) in in Nat Rev Gastroenterol Hepatol

#Epigenetics #Review #CRC #Cancer

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - DCAF7 regulates hematopoietic stem cell function and differentiation through polycomb repressive complex 1 modulation https://t.co/TdVYTATHzy

Johanna Melo-Cardenas & John Crispino in Nat Commun

#Epigenetics #Chromatin #StemCells
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https://t.co/WmSYDGXnzb

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - Cell-cycle-driven epigenetic resetting maintains meristematic cell fate for shoot branching https://t.co/Ti5yd4COMA

Yuling Jiao (@PKU1898) and Ying Wang (Capital Normal University) in @NaturePlants

#Epigenetics #Plants #Chromatin #CellCycle

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - Lysine crotonylation acts as an epigenetic switch for glutamate neurotransmission and spatial memory https://t.co/QxqNHcEApb

@TedAbelneuro and @Snehajyoti3 (@UIowaNeuro) in PNAS

#Epigenetic #Chromatin #Crotonylation
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See more: https://t.co/WmSYDGXnzb

[Vijay Sankaran @bloodgenes]

Delighted to share our new work in @CellStemCell! Transient epigenome editing durably silences genes in human 🩸 stem cells and mature progeny, without changing 🧬. Congrats to @lrbzldz & our collaborators!

https://t.co/xvxkmC9dz9

[Epigenome Technologies Inc. @EpigenomeTech]

We have recently expanded our single-cell epigenetics assays!

Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIP-seq platform

#SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq

Learn more here: https://t.co/d8LjBhvWo4

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - BAZ2A-induced epigenetic states in cancer cells fuel palmitate accumulation in the tumor microenvironment driving CAR-T cell exhaustion https://t.co/L9td9skjSp

#Epigenetics #TME #Cancer #CART #BAZ2A #Metabolism #Chromatin

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - Phase separation of SMARCAL1 orchestrates epigenetic reprogramming and methionine metabolism to foster radioresistance and immunosuppression https://t.co/TMwI9pWX5F

#Epigenetics #SMARCAL1 #PhaseSeparation #Metabolism #Resistance

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - Enhanced cfDNA methylation profiling by detection and correction of jagged ends https://t.co/ouNs0QEPmP

Maximilian Diehn & @AshAlizadeh (@Stanford) in @naturemethods

#Epigenetics #DNAm #Methods
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Cancer, immunology, & aging; https://t.co/WmSYDGXnzb

[Epigenome Technologies Inc. @EpigenomeTech]

Download our poster to learn how we applied Droplet Paired-Tag to Alzheimer's disease post-mortem brain tissue to reveal specific cellular changes and potential therapeutic targets

#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers

https://t.co/QUo15hhc2z

[Epigenome Technologies Inc. @EpigenomeTech]

Epigenetics Update - Genetic variants shape single-cell chromatin accessibility and disease risk https://t.co/Q9Poxp7hDl

@anglixue and @drjosephpowell (@GarvanInstitute) in Nature

#Epigenetics #Chromatin #SingleCell #DiseaseRisk
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https://t.co/WmSYDGWPJD