Eric Xing

Researcher, educator, entrepreneur, and administrator in computer science, artificial intelligence, and healthcare.

[Cecile Tamura @ceciletamura]

Prof. @ericxing , President of Mohamed bin Zayed University of Artificial Intelligence (@mbzuai), in a thought-provoking discussion w/ @cecileramura, Head of Community, @ploutosai

https://t.co/dKTHMIIXJp

[elvis @omarsar0]

// Critique of the Agent Model //

Finally, a paper that tries to define what an agent is and what agency consists of.

Good read overall. (great bookmark)

The word agent now covers everything from a for-loop with tool calls to speculative machine superintelligence.

Eric Xing and colleagues ask where automation ends, and agency begins.

Drawing on Descartes and on science-fiction portrayals of autonomous beings, they analyze agent architectures along five dimensions: goal, identity, decision-making, self-regulation, and learning.

The argument is that genuine agency requires these structures to hold together in a specific way. Great paper overall, providing a vocabulary for arguing about what is and is not an agent.

Paper: https://t.co/qFvMxWd5cq

Learn to build effective AI agents in our academy: https://t.co/1e8RZKs4uX

[keithofaptos @keithofaptos]

https://t.co/t3ugj82agj

[Eric Xing @ericxing]

We discussed foundational issues underlying how to make truly “agentive” systems.

https://t.co/sgO2XjDg0b

[Eric Xing @ericxing]

A companion paper to the critique of agent model paper.

https://t.co/4tEIM7TO3u

[Eric Xing @ericxing]

Decoding the “Critique of Agent Model” Paper https://t.co/V3Ry8HVnYs

[Eric Xing @ericxing]

The outlook of an AI-driven Digital Organism (AIDO), such as a virtual cell (VC), has recently captivated much excitement and imagination from both AI and Biology communities, but there remain many open questions, in particular, what model presents the best path to realize an #AIDO or a #VC?

In this paper we present a definition of the virtual cell based on World Model — an architecture recently emerged in AI that supports advanced capabilities such as action-conditioned simulation, dynamic state-evolution, counterfactual reasoning, and long-horizon planning in complex dynamic environments. When applied to biological scenarios, a world model of the virtual cell is a generative model that simulates biological possibilities of a cell under any natural or artificial interventions and environments.

Such a virtual cell world model (VCWM) contrasts predictive foundation models on specific tasks, such as gene-expression perturbation prediction, as seen in some recent definitions of the virtual cell. At the same time not every biological foundation model built on sequence or structure or expression only can be repositioned as a world model if there is no multi- or pan-modality, stateful embedding, continuous action-conditioning, and dynamic state-transition and rollout.

We presents a novel architecture for #VCWM based on the GLP (generative latent prediction) framework that enables simulated cell as an end-to-end platform. Stay tuned for the release of the first implementation of VCWM from @genbioai soon.

@dasongle, @zivbj, @ElijahCole, @probablybots, @EuxhenH, @cfeinau, @deboramarks, @fabian_theis, @mmbronstein, @pkoo562

https://t.co/76bZm53ML4

[Eric Xing @ericxing]

With the rise of LLM systems marketed as "coding agents", "AI co-scientists", etc. that promise to drive up productivity, and at the same time outcry of "existential" concerns that AI escaping human control with destructive power under a speculative "machine agency" against humans, there has been lots of confusion about “What is an agent?” and “What constitutes agency?” It has become essential to clarify where automation ends and agency begins.

Also recently, developments in world models, action models are trending to mixing future prediction/simulation and action/plan generation altogether within a single architecture such as a VLM, conflating reward-driven action selection with fidelity-driven next-state prediction, undermining the reliability of both planning and simulation.

In this paper we analyze agent architectures along the axis of goal, identity, decision-making, self-regulation, and learning, and argue that genuine agency requires these structures to be internalized within the system itself rather than assembled through external scaffolding. We propose a “Goal-Identity-Configurator” (GIC) architecture for a general-purpose agent model, combining hierarchical goal decomposition, identity evolution, simulative reasoning grounded in a separately trained world model, learned self-regulation, and self-directed learning from both real and simulated experience.

Auditability, controllability, and safety of systems that possess greater autonomy and "agency” but remain under human oversight, can be better built with the GIC architecture that offers transparency, modularity, and checkpoints.

@mdeng34 , @jinyuhou0

https://t.co/jDA4PJIDwm

[GenBio AI @genbioai]

An excellent piece in @Nature on the promise and challenges of virtual cells, including insights from GenBio AI's @ericxing and @Prof_Lundberg on why multi-scale, multimodal approaches are the future, and why world models are key to building them. Learn more → https://t.co/UeC31EPbqj

[Mingkai Deng @mdeng34]

We agree that the world model should be a simulator that supports decision-making, not rendering beautiful images/videos.

Our difference is in how the world state should be represented.

Should the world be anchored in Gaussian splats and physics engines for program-as-simulator? Or in learned representations for model-as-simulator?

We believe the latter is a more scalable, bitter-lesson-pilled approach.

More in our position paper "Critiques of World Models" coauthored with Prof. @ericxing and @jinyuhou0

https://t.co/NqnxGtKNBL

[Institute of Foundation Models @IFM_MBZUAI]

1/4
Frontier LLMs are converging on adaptive reasoning.

But controlling how much to think is not the same as controlling what kind of thinking to do.

SR²AM introduces self-regulated simulative reasoning: an agent that simulates possible futures through a world model and learns when that simulation is worth the cost.

[CMU School of Computer Science @SCSatCMU]

Congrats to Parallel Data Lab researchers including SCS faculty member Eric Xing on receiving the Test of Time Award during the 2026 EuroSys Conference!

https://t.co/7f1PZ68aqu

[Mingkai Deng @mdeng34]

Frontier LLMs are converging on efficient, adaptive reasoning. Opus 4.7 lets the model decide how deeply to reason. GPT-5.5 achieves strong results with fewer reasoning tokens.

We study a related but more structural question: what 𝗸𝗶𝗻𝗱 𝗼𝗳 𝗿𝗲𝗮𝘀𝗼𝗻𝗶𝗻𝗴 should we adapt?

Last year in SiRA (upper figure), we showed that simulative reasoning (System II), which uses a 𝘄𝗼𝗿𝗹𝗱 𝗺𝗼𝗱𝗲𝗹 to evaluate consequences of actions, yields up to 124% improvement over reactive baselines (System I), and that strong reasoning models (o1, o3-mini) fail as planners without this structure.

In our new paper SR²AM (lower figure), we add a learned 𝗰𝗼𝗻𝗳𝗶𝗴𝘂𝗿𝗮𝘁𝗼𝗿 (System III) that self-regulates when to simulate, how far ahead, and when to skip planning entirely.

Efficient reasoning is not just shorter reasoning: it is better allocation of simulation.

[Mingkai Deng @mdeng34]

This is a prototype using language-based world models. Stay tuned for our next steps on multimodal and physical world models.

The concept of a configurator, which decides when and how deeply to engage a reasoning process, is not specific to planning, but extensible to learning and adaptation going forward.

📄 SR²AM: https://t.co/LKeXZFN8Hh
📄 SiRA: https://t.co/5JzLSEu4nO
🌐 Project: https://t.co/1CUlEdFMxY
💻 Code: https://t.co/JSBoERYHaB

🤗 SR²AM-v0.1-8B: https://t.co/b1kkuvFL6k
🤗 SR²AM-v1.0-30B: https://t.co/PES00q6a4J

Joint work with @jinyuhou0, @larasnevess, @varad0309, @tw_killian, @waterluffy, @ericxing

[MBZUAI @mbzuai]

MBZUAI and the United Arab Emirates Government have signed a strategic collaboration agreement.

As the Strategic Knowledge Partner, MBZUAI will support the UAE's national initiative to deploy agentic AI across 50% of government services, training 80,000 federal employees and delivering executive programs for government leaders, reinforcing the UAE's commitment to becoming a global leader in AI-enabled governance and public sector innovation. The collaboration will advance AI readiness, literacy, and executive capability building across UAE federal government entities and ministries, and driving the responsible adoption of generative and agentic AI technologies.

In the presence of H.E. Mohammad Abdullah Al Gergawi, Minister of Cabinet Affairs, and H.E. Khaldoon Khalifa Al Mubarak, Secretary General of the Artificial Intelligence and Advanced Technology Council and Chairman of MBZUAI’s Board of Trustees, the MOU was signed by H.E. Ohood Khalfan Al Roumi, Minister of State for Government Development and the Future and Chairwoman of Federal Authority for Government Human Resources (FAHR), and Prof. Eric Xing, MBZUAI President and University Professor.

[Institute of Foundation Models @IFM_MBZUAI]

Zihan Liu, Technical Lead for the PAN world model at IFM’s Silicon Valley Lab, is joining us at @Stanford on May 21 to share how he and his team build interactive, long-horizon world simulations.

[Institute of Foundation Models @IFM_MBZUAI]

Hector Liu, Director of IFM’s Silicon Valley Lab, is joining us at @Stanford on May 21 to share how he and his team build and deploy IFM’s reasoning and world models.

[The Royal Family @RoyalFamily]

A very special delivery for David Attenborough, beloved by people (and animals) everywhere 💚

To honour Sir David’s 100th birthday, His Majesty The King is supported by a cast of stars from British nature to relay his handwritten message in time for the celebration at the Royal Albert Hall.

Watch David Attenborough’s 100 Years on Planet Earth on @BBCiPlayer.

https://t.co/yZojhLlUXp

[Eric Xing @ericxing]

Glad to see @mbzuai , a university 5 years old, is in this list of top contributors alongside world leading universities. Contributions to my colleagues.

[ℏεsam @Hesamation]

someone analyzed all 5000+ accepted papers at ICLR 2026, and it's a good signal who's pushing the research of AI:
> China has surpassed the US with 43.7% of the papers
> Europe's contribution is surprisingly small (5.3% including UK)