Very excited to share our story describing a novel druggable epigenetic dependency in pediatric H3K27M DMG. Hoping this would become a therapeutic opportunity for these pediatric patients in the future! Thank you to my post-doc mentor, @FilbinMariella
In recognition of Brain Cancer Awareness Month, the #CancerMoonshot is convening a forum at the White House to accelerate progress on two of the deadliest brain cancers, Glioblastoma and Diffuse Intrinsic Pontine Glioma. Tune in at 1pm tomorrow (Thursday): https://t.co/EfoGuMlEyR
The #Hallmarks of #Cancer constitute a theoretical framework for rationalizing the vast complexity of cancer & its underlying mechanisms. Here we discuss nervous system-cancer interactions ‘‘enabling’’ hallmark functions & consequent cancer pathogenesis
https://t.co/CBPuJgFBxS
1/ Pre-print alert! Our new study led by talented @StanfordMed student @SavchukSol together with @michelle_monje illustrates that neuronal activity regulates the progression of small cell lung cancer #SCLC in the lung and brain. #CancerNeuroscience. 🧵… https://t.co/32lGVVbVu0
I came to study Ewing sarcoma in memory of my friend Bryan. It has been such a privilege to study this disease and I am so honored to have this work published. https://t.co/s4lRrhxokt
Check out two new publications on Ewing sarcoma and ETV6 in @NatureCellBio from our lab and @ChrisVakoc. Excited to see them both in press!
https://t.co/eqJ7xEXMc3
In the Spotlight: Epigenetic rewiring underlies #SMARCA4-dependent maintenance of progenitor state in pediatric H3K27M diffuse midline #glioma, by Mary Clare Beytagh and William Weiss.
https://t.co/lfo4ZdvYTA
@UCSF
🎉 PUBLISHED TODAY @NatureGenet
📰 The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location
🧑🏽🤝🧑🏻 @FilbinMariella@IlonLiu@Eshini_Pandit and colleagues
👇🏽
https://t.co/o302JHvv13
The December issue of @CD_AACR is now online! The newest cover to add to my office wall highlights work by @JunQILab@FilbinMariella and colleagues & Zhiguo Zhang and colleagues showing H3K27M-mutant #glioma is dependent on SMARCA4 🧠https://t.co/Q4ZOeGt55R
Very excited to share our story describing a novel druggable epigenetic dependency in pediatric H3K27M DMG. Hoping this would become a therapeutic opportunity for these pediatric patients in the future! Thank you to my post-doc mentor, @FilbinMariella
Thrilled to see our joint story on VRK1 dependency in neural-lineage cancers (including DIPG) out! This was a wonderful collaboration with Bill Hahn and Kim Stegmaier, led by our three fantastic postdocs - grateful to be at @DanaFarber where cross-disease projects are possible!
It's out! Our new paper on exploring the effects of subclonal interactions between diffuse midline glioma cells and their ability to spread using a computational and experimental framework we developed. @Ket_kess@AndreaSottoriva@ICR_London@CellReports
https://t.co/m2z67mHkZP