EXTRIP

The EXTRIP mission is to provide evidence-based recommendations on the use of extracorporeal treatments for toxin removal in poisoning.

[EXTRIP @ExtripWorkgroup]

@ThommyTox @EMPoisonPharmD I sound like a broken record. VD= 30L/kg. You're not removing any bupropion with MARS (or otherwise)

[the EMCrit Crew @emcrit]

EMCrit 370 - Extracorporeal Therapies for Poisoning #ExTRIP #NephMadness
A panel of brilliant nephrologists discuss RRT for the Poisoned Patient.
Modality choice, how to consult, access, hemodynamic stability and so much more!
[#FOAMed]
https://t.co/otu1mDutdt

[EXTRIP @ExtripWorkgroup]

@JEGAYTAN90 @ArgaizR @alfonsogindl @hydws_ @Elena_Cervants @AJKDonline @NephMadness @weddellite @DrDianeC @MarcGhannoum @NefroINCMNSZ @medicinterna There's a cool case report of someone using isopropanol (a less toxic alcohol) as an antidote for EG poisoning (although I would contend that a cheap scotch bottle is easy enough to find).

[EXTRIP @ExtripWorkgroup]

@hswapnil @weddellite @DrDianeC @JEGAYTAN90 Sorry, was late to the party! Everything said here for glucarpidase is correct. Removes MTX from the blood, but not where it hurts (inside the cells). If AKI has occurred, it's probably too late. And no data of improved outcomes. Obs data suggests outcomes unchanged.

[EXTRIP @ExtripWorkgroup]

@baileympaterson Happy to read the answers. Maximize clearance. You're not removing net fluid. HD is preferred.

[EXTRIP @ExtripWorkgroup]

Stop the press! Our latest guideline: when to use dialysis for ethylene glycol poisoning. Perhaps our best paper yet. Hundreds of articles included, thousands of hours of work. https://t.co/FF7MK2UU65

[EXTRIP @ExtripWorkgroup]

@Sthanu5 3) Nothing corrects metformin-associated acidemia as quickly as HD

[EXTRIP @ExtripWorkgroup]

@Sthanu5 2) The VD of metformin in AKI is actually quite low and you will remove it with HD.

[Sociedad Valenciana de Nefrología @SVNefro]

Si eres un #believer de los #some en la formación continuada tienes que seguir a @ExtripWorkgroup:
Perfil que se dedica a informar sobre las técnicas de depuración extracorpórea en casos de envenenamiento

https://t.co/AVrTyZYSY4

@SENefrologia @senjoven @SOMANEorg @nefrocat

[AJKD @AJKDonline]

Extracorporeal Treatment for Gabapentin and Pregabalin Poisoning: Systematic Review and Recommendations From the @ExtripWorkgroup

https://t.co/yqF6stVpdo (FREE temporarily)

[Matthew Zuckerman, MD @matthew608b]

Checkout this handout from todays #AAEM22 talk on Toxic Ingestion and Dialysis. Thanks @ExtripWorkgroup for such great guidelines.

https://t.co/fbItrVvvTZ

[EXTRIP @ExtripWorkgroup]

Should we dialyze a patient who is toxic from high-dose or oral methotrexate? The jury is now out: https://t.co/2gnecusnSk
Or on our website: https://t.co/stzzckORdS

[EXTRIP @ExtripWorkgroup]

@drmjkulkarni I would be extremely dubious about any potential benefit.

[AJKD @AJKDonline]

Extracorporeal Treatment for Gabapentin and Pregabalin Poisoning: Systematic Review and Recommendations From the @ExtripWorkgroup

https://t.co/VjhvpaB8Uc (FREE temporarily)

[AJKD @AJKDonline]

Extracorporeal Treatment for Gabapentin and Pregabalin Poisoning: Systematic Review and Recommendations From the @ExtripWorkgroup

https://t.co/yqF6stVpdo

@sgosselinmd

[EXTRIP @ExtripWorkgroup]

@MPCToxtidbits @EdinClinTox All but 1 patient in the TK table for gabapentin had impaired kidney function. All had impaired kidney function for pregabalin. Half-life was during ECTR so includes ECTR and endogenous function, the latter being quite low presumably

[EXTRIP @ExtripWorkgroup]

Just out: EXTRIP's recommendations for dialysis in gabapentin / pregabalin poisoning https://t.co/fMj0VppqqT

[Swapnil Hiremath @hswapnil.medsky.social @hswapnil]

not simu-live tweeting as absolutely cannot do justice to the excellent @ExtripWorkgroup session at #KidneyWk organized by @weddellite

but want to highlight this

@DavidJuurlink quotes the IBCC on the big screen! @PulmCrit

Salicylate is a huge mimic!

[EXTRIP @ExtripWorkgroup]

The Extrip guideline for baclofen is dedicated to @Nephro_Sparks