Geoff Faulkner

Professor, University of Queensland. Retrotransposons and genomics.
Views my own. Scholar publications:

[Geoff Faulkner @Faulkner_Lab]

After years of telling visitors to Brisbane what an awesome place it is for fun* adventures, I've decided to make a list in the order I remember them of my favourite places to go for ease of reference. Here goes ...

(*definition of fun may vary)

[Geoff Faulkner @Faulkner_Lab]

@TeamLINE1 @TrinaKarabi @SDStatePharmacy Congrats on this important work (am catching up on reading today). Do you know if Tgf21 has the YY1 mutation you note in the Gf1 monomer? The 75% reduction is consistent with what we saw in humans after YY1 site truncation (https://t.co/a7aOeCPmXQ) so could be cell type specific

[Geoff Faulkner @Faulkner_Lab]

@marcotrizzino @ControllingLMNT @BrugmannLab Congrats!

[Geoff Faulkner @Faulkner_Lab]

@JakobssonLab @Dev_Cell Thanks Johan

[Geoff Faulkner @Faulkner_Lab]

Reposting comment on preprint of this @Dev_Cell paper. Stats done on technical replicates of L1 KD to make small absolute changes seem significant. Biological replicates were available but not used for stats, why? Because p>0.05? I don't understand this.

https://t.co/DMsoTLzr3S

[Geoff Faulkner @Faulkner_Lab]

I doubt the stated phenotype here is due to changes in L1 mRNA. The ASO and CRISPRi KD approaches (Figs 1, S1, S2) reduce L1 expression by <10% and these small changes are noted as efficient and significant KD. Stats were done on tech reps to give p<0.05

https://t.co/npX6YyPLXq

[Geoff Faulkner @Faulkner_Lab]

@PRAndersen @RippeiH More interesting reading here and food for thought too, thanks. Also, as per Maslow's hammer, a lot of these systems likely evolved to control transposons in some way but now work somewhat differently on genes.

[Geoff Faulkner @Faulkner_Lab]

Thoughtful and rigorous work from @RippeiH and @PRAndersen teams looking at PAF1C and transcriptional termination. Interesting for me to look at "the other end" of transcription for a change. I wonder what brings tTAF and tPAF together?

https://t.co/sryrqH1eWo

[Peter Andersen @PRAndersen]

1/ Our lab’s first preprint found a wonderful journal home! 🎉

Our paper explores the role of testis-specific transcription factors in Drosophila and reveals broad functional connections between tissue-specific paralog proteins.

📝: https://t.co/Qr09ScxueX

[Centre for Genomic Regulation (CRG) @CRGenomica]

🚀 Join the CRG as a Junior Group Leader in Quantitative Cell Biology! 🧬

We’re seeking passionate leaders to tackle fundamental biological questions using cutting-edge multidisciplinary approaches. Enjoy generous core funding, state-of-the-art facilities, and a collaborative environment.

📅Apply by Oct 15!

ℹ️Details: https://t.co/25WRC7lKEQ #CRG

[Marco_Trizzino Lab @marcotrizzino]

The 5-year postdoc position in my lab is now "live" for applications! Deadline to apply is November 3rd: https://t.co/Mv9zu9t6mT

Please RT

[Geoff Faulkner @Faulkner_Lab]

I doubt the stated phenotype here is due to changes in L1 mRNA. The ASO and CRISPRi KD approaches (Figs 1, S1, S2) reduce L1 expression by <10% and these small changes are noted as efficient and significant KD. Stats were done on tech reps to give p<0.05

https://t.co/npX6YyPLXq

[Geoff Faulkner @Faulkner_Lab]

@MRSantosLab Hi Miguel I have some questions:

In Fig 1D, S2A and S2E what is each data point? A cell?

What is the absolute change in L1Hs expression caused by the ASO or CRISPRi?

In Fig S2C what is the mean value for each of the 3 groups, instead of Z-score?

Thanks.

[Charlie Bell @charles_bell92]

I am looking for a motivated PhD student who is interested in understanding the fundamentals of gene regulation. They will be working directly with me on a DECRA funded project (scholarship guaranteed for domestic students). DM me if you know of anyone interested, including you

[Geoff Faulkner @Faulkner_Lab]

@RBerrens @VictorBillon1 @EMBO Looks great!

[Joanna W Jachowicz @jwjach]

interested in 3D genome organization during early development? want to understand how it is shaped by RNA? you like data analysis and developing new computational tools? 🧬💻🧐

With @golobor we are recruiting a PhD student/intern to work with us at @IMBA_Vienna

[Geoff Faulkner @Faulkner_Lab]

Congrats @JuanManuelBotto for passing your final PhD milestone and welcome to the lab @barunlz !

[Christopher Douse @ch_douse]

Delighted that this is finally out! Thanks to @Faulkner_Lab @todd_macfarlan and the other reviewer for good and constructive comments that arrived in my inbox the day after my second child was born... paper here https://t.co/YfN3uIo7XI. Short reflection on new stuff...

[Max Planck Society @maxplanckpress]

Calling all emerging scientists - it’s time to send us an application! 😉😎 Lead your own #MaxPlanck Research Group w/ €2.7M in funding over 6 yrs, full independence & resources to hire staff. State-of-the-art infrastructure awaits you!🌟 Apply today➡️https://t.co/cHxPLyRj9x

[Heng Li @lh3lh3]

Preprint on "BWT construction and search at the terabase scale". We can compress 100 human genomes to 11GB in 21 hours, find SMEMs with it, do affine-gap alignment and retrieve similar local haplotypes. 7.3Tb commonly sequenced bacterial genomes ⇒ 30GB https://t.co/DiRwZNHVVa

[Johan Jakobsson @JakobssonLab]

Proud to have contributed to this fantastic study led by @ch_douse . HUSH for the world!

https://t.co/dEK1Qoiob7

[Australasian Epigenetics Alliance @AEpiA]

1/11 Welcome to our August ECR spotlight! This month we get to know Charles Bell @charles_bell92 who works in the Faulkner lab @Faulkner_Lab at the Mater Research Institute @MaterResearch and University of Queensland.