Felix Grünberger

Postdoctoral Researcher at University of Regensburg | Microbiology | Transcriptomics in prokaryotes

[Richard Stöckl @richard_stoeckl]

Do you want to publish your genomes to @seq_code ?
Maybe my #Snakemake pipeline could be of interest to you! It quickly lets you check if your assemblies reach the required criteria and gives you an easy to read report like this as an output 🙂
https://t.co/yH7FM4YOfi

[Dina Grohmann @DinaGrohmann]

I never imagined that there would be a paper from my lab titled "The structural basis of ..." but first author @2Magdalena1 and the very collaborative archaeal RNA polymerase made it work 😀. Read it here: https://t.co/QNKxYe9xxF. Thank you also to our partners @lab_engel 🤝!

[Dina Grohmann @DinaGrohmann]

Happy new year and happy new pre-print https://t.co/2oPeCCISem with cryo-EM structures of the archaeal RNA polymerase in its apo state and during elongation w/ and w/o Spt4/5 featuring some distinct archaeal features. #Archaea #cryoEM #transcription Some key findings 🧵

[bioRxiv @biorxivpreprint]

Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment https://t.co/bhvFCw0BZq #bioRxiv

[Felix Grünberger @FelixGrunberger]

@runhuahan @mbiojournal @DinaGrohmann Thanks for checking out our papers! I'm glad you found the figures interesting. Your feedback is much appreciated.

[Felix Grünberger @FelixGrunberger]

Exciting News! Our latest article is now available to the public @mbiojournal!
Check out how we used correlative #transcriptomics/#proteomics to discover how hyperthermophiles react to extreme thermal stress🥶🥵
@DinaGrohmann
https://t.co/2IYnf2GlWE

[Dina Grohmann @DinaGrohmann]

Recently, we published two stories that add some new data to our understanding of archaeal transcription, e.g. insights into transcription termination, regulation of archaeellum operon expression by EarA and co-transcriptional binding of SmAP. Short🧵with some key findings...

[Felix Grünberger @FelixGrunberger]

Special thanks to all the co-authors (@ZubeirElAhmad
@MartinFenk, ...) and our collaboration partners @christof_lenz & Henning Urlaub for their support 🙌

[Rani Baes @Rani_Baes]

🔥Heat shock response in #Sulfolobus🔥

👉In this new #mbio paper we combine omics-experiments to shed light on underlying regulatory mechanisms!

It was a great collaboration between @MicrVub, @SfcLab, @DinaGrohmann, @FelixGrunberger,...!

https://t.co/cKAluEloV5 @fwo @VUBrussel

[Felix Grünberger @FelixGrunberger]

Thrilled to have been part of this exciting journey investigating the heat shock response in Sulfolobus🔥, now published in #mBio!
Really enjoyed diving into data analysis discussions for this story with @Rani_Baes! Congrats!

[Archaea Power Hour - Europa @APH_Europa]

Hot from the press 🔥... Heat shock response in thermophiles 🤯@ranibaes @PeetersEveline @DinaGrohmann @SfcLab !
Transcriptional and translational dynamics underlying heat shock response in the thermophilic crenarchaeon Sulfolobus acidocaldarius | mBio https://t.co/nfgOoQQ6NY

[Dina Grohmann @DinaGrohmann]

Working with my physicist colleagues at the @uni_regensburg is a privilege and a lot of fun. The @FGiessibl pushed their high-end qPlus sensor AFM technique to image archaeal S-layers ... here is the result 😍https://t.co/WgK6kd3Aa2 (just accepted in JPCB). @DanielaTarau

[SFC_Lab @SfcLab]

📢Now the manuscript is available in its final formatted version🤩
https://t.co/frZdiuZWHD

[CNRS Biologie @CNRSbiologie]

#ResultatScientifique🔎| Explorer les secrets du métabolisme de l'ARN des micro-organismes extrêmophiles

🤝 @CNRS @CNRSIdFSud @SfcLab @Polytechnique
✍️ Sébastien Ferreira-Cerca et @DinaGrohmann
📕 @RNAJournal | https://t.co/LapBG32OYv
https://t.co/Ott0dzNnho

[Michael T Wolfinger @mtwolfinger]

The #ViennaRNA Package 2.6 is here with awesome updates💥 Salt corrections for mono-valent cations & support for modified bases like pseudouridine. BTW, our #Python interface comes with all-new, nice & clean documentation. 🐍📖https://t.co/vWUNvvE7w4 #RNA #ComputationalBiology

[Lars Barquist @LBarquist]

Check out our new preprint, where we started off building a statistical model to investigate the effects of RBPs on RNA stability, and ended up finding out that average RNA half-life in bacteria is less than a minute -- less than 1/3 of previous estimates https://t.co/RVUWGORYK0

[Felix Grünberger @FelixGrunberger]

3⃣ Transcriptome and sequence feature analysis reveal heterogeneous expression profiles of major archaellins in Thermococcales fine-tuned by intergenic terminator sequences

[Felix Grünberger @FelixGrunberger]

Ever wondered how Archaea regulate the expression of their flagella-like appendages, known as archaella?
Check out our new preprint on EarA-based regulation in Pyrococcus, now available on bioRxiv!
@richard_stoeckl @DinaGrohmann https://t.co/URNjq7kZYk #Archaea #Microbiology

[Felix Grünberger @FelixGrunberger]

2⃣ Long-read sequencing analysis provides high-resolution insights into transcriptional regulation of the arl gene cluster in P. furiosus

[RNA @RNAJournal]

Nanopore-based RNA sequencing deciphers the formation, processing, and modification steps of rRNA intermediates in Archaea. #Nanopore #Microbiology #Archaea
https://t.co/gI4m9DMqSi