Fernando Lara Freire, MD

IMG Ecuador 🇪🇨 Pathologist on the way! 🔬
Creator @thepathpost 🦠🧫 Loving reading, soccer and teaching 📚 AAMC ID: 16640823

[Fernando Lara Freire, MD @Fernando02MD]

The time has finally come!

Hello #PathTwitter 👋 I am Fernando Lara Freire, an IMG from Ecuador 🇪🇨 applying for #PathMatch2026 🔬

Passionate about discovery and teaching!

Outside Pathology I enjoy reading, soccer and travelling 🍂

Excited to connect with you all!

[Fernando Lara Freire, MD @Fernando02MD]

@camilin86 @JhonParedes9 Fernando Lara Freire
Vamos LDU!! 🔥🏆
❤️🤍

[NASA @NASA]

Hello, Moon. It’s great to be back.

Here’s a taste of what the Artemis II astronauts photographed during their flight around the Moon. Check out more photos from the mission: https://t.co/rzM1P0QbOl

[Exito Y Sabiduria @Exitoysabiduria]

Las mentes más brillantes
nunca fueron completamente normales.

[Doc Navarrow @DocNavarrow]

🙆‍♀️A 42-year-old woman with septic shock and coma undergoes brain MRI after status epilepticus.

🧠Supratentorial cortical abnormalities are present, but the cerebellum shows contralateral involvement despite no primary lesion.

Which phenomenon explains this crossed pattern?

[Elizabeth Montgomery, MD @LizMontgomeryMD]

My gracious! A sneaky presentation of metastatic mammary lobular carcinoma as a pancreatic mass.

[Elizabeth Montgomery, MD @LizMontgomeryMD]

Compare esophageal epidermoid metaplasia with the hyper/parakeratosis associated with reflux. There is a bit of reactive Barrett mucosa at no extra charge.

[Dr Kamlesh Darji @DrKamleshDarji1]

A slide never lies. It only waits patiently for the right pathologist to read it.

[NeuroWoodworks @NeuroWoodworks]

One of my next commissions will be this neuronal blue bird, composed of 17 individual neurons. 🧠🔬

[UMiami Pathology @UMiamiPathology]

Bile duct brushing: note the difference between the reactive ducts (left) and carcinoma (right).

[Elizabeth Montgomery, MD @LizMontgomeryMD]

The presence of esophageal ducts in a mucosal biopsy is a clue that the sample was derived from the tubular esophagus.

[Fernando Lara Freire, MD @Fernando02MD]

So happy to have received this news!! 😁

[Brenda Baltodano MD ☕️ @brenbaltodanomd]

So excited to share this wonderful news! 🥳🥳🥳 @MD_JosselynV @Fernando02MD we did it!! #pathology #uscap #Match2026 #PathTwitter #pathx

[Nithin Kamath @Nithin0dha]

If there’s one thing I wish I had done differently when I was hit by a stroke last January, it would be to go to the hospital immediately, within the Golden Hour (<4.5 hours), instead of thinking I could just sleep it off.

This “nothing will happen to me” attitude is common, especially among those under 50. But the truth is, strokes are rising sharply, up to nearly 30% of all strokes in the last few years, among 30 to 50-year-olds.

When it comes to strokes, time is brain; every minute counts.

Thanks to @timesofindia for featuring this on World Stroke Day today.

[Dr.Marlon Villanueva™ 🩺 𝕏 @MarlonVFZR]

🧠𝗦𝗶𝘀𝘁𝗲𝗺𝗮 𝗡𝗲𝗿𝘃𝗶𝗼𝘀𝗼 𝗖𝗲𝗻𝘁𝗿𝗮𝗹🧠
⬇️⬇️⬇️⬇️

🔹 𝙊𝙧𝙜𝙖𝙣𝙞𝙯𝙖𝙘𝙞𝙤́𝙣 𝙢��𝙩𝙤𝙧𝙖 𝙟𝙚𝙧𝙖́𝙧𝙦𝙪𝙞𝙘𝙖:
•𝙋𝙧𝙚𝙛𝙧𝙤𝙣𝙩𝙖𝙡: planificación y decisión.
•𝙋𝙧𝙚𝙢𝙤𝙩𝙤𝙧𝙖 (𝙋𝙈𝘾): prepara movimientos.
•𝙈𝙤𝙩𝙤𝙧𝙖 𝙨𝙪𝙥𝙡𝙚𝙢𝙚𝙣𝙩𝙖𝙧𝙞𝙖 (𝙎𝙈𝘾): coordina movimientos bilaterales.
•𝘾𝙤𝙧𝙩𝙚𝙯𝙖 𝙢𝙤𝙩𝙤𝙧𝙖 𝙥𝙧𝙞𝙢𝙖𝙧𝙞𝙖 (𝙈1): ejecuta movimiento → vía piramidal → 𝙢𝙚́𝙙𝙪𝙡𝙖 𝙚𝙨𝙥𝙞𝙣𝙖𝙡 → músculos.

🔹 𝙑𝙞́𝙖𝙨 𝙢𝙤𝙩𝙤𝙧𝙖𝙨:
•𝙋𝙞𝙧𝙖𝙢𝙞𝙙𝙖𝙡 (𝙘𝙤𝙧𝙩𝙞𝙘𝙤𝙚𝙨𝙥𝙞𝙣𝙖𝙡): control fino y voluntario.
•𝙀𝙭𝙩𝙧𝙖𝙥𝙞𝙧𝙖𝙢𝙞𝙙𝙖𝙡: postura, tono y coordinación (núcleos basales + cerebelo).

🔹 𝙂𝙖𝙣𝙜𝙡𝙞𝙤𝙨 𝙗𝙖𝙨𝙖𝙡𝙚𝙨:
•𝘊𝘢𝘶𝘥𝘢𝘥𝘰, 𝘱𝘶𝘵𝘢𝘮𝘦𝘯, 𝘨𝘭𝘰𝘣𝘰 𝘱𝘢́𝘭𝘪𝘥𝘰.
•Regulación del inicio y precisión del movimiento.
•𝙎𝙪𝙨𝙩𝙖𝙣𝙘𝙞𝙖 𝙣𝙞𝙜𝙧𝙖: dopamina → facilita vía directa; su degeneración → Parkinson.

🔹 𝘾𝙚𝙧𝙚𝙗𝙚𝙡𝙤:
•Coordina movimiento, equilibrio y tono.
•Lesión → ataxia, dismetría.

🔹 𝙏𝙧𝙤𝙣𝙘𝙤 𝙚𝙣𝙘𝙚𝙛𝙖́𝙡𝙞𝙘𝙤:
•Integra vías motoras y sensoriales.
•Tractos: vestibuloespinal (equilibrio), rubroespinal (control fino), reticuloespinal (postura), tectoespinal (reflejos visuales/auditivos).

👉 𝙀𝙨𝙚𝙣𝙘𝙞𝙖 𝙘𝙡𝙞́𝙣𝙞𝙘𝙖:
La corteza planifica → ganglios basales y cerebelo ajustan → médula ejecuta → movimiento preciso y coordinado.

👇🏼👇🏼👇🏼👇🏼
📚📖#ClubCrit 👉 [https://t.co/kDo5QpqM9K]

#SNC #CNS #NeuroX #ClubCrit #MedTwitter #CritCare #UCI #ICU #CriticalCare #Diagnóstico #icu #intensivecare #MedTwitter #diagnosis #management #Riesgo #ICU #POCUS #UCI #Tratamiento #MedicinaBasadaEnEvidencia #Emergencia #Terapia #MedEd #Medicina #Emergencias #FOAMed #FOAMcc #MedTwitter #CriticalCare #MedEd #CuidadoCrítico #MedX #IntensiveCare #EducaciónMédica #MedIntensiva #MedXCommunity #MedicinaCrítica #MedED #CritCare #ICUManagement #MustRead #LecturaRecomendada

[Dr.Marlon Villanueva™ 🩺 𝕏 @MarlonVFZR]

🪨𝗧𝘂𝗺𝗼𝗿𝗲𝘀 𝗽𝗿𝗶𝗺𝗮𝗿𝗶𝗼𝘀 𝗱𝗲𝗹 𝗦𝗡𝗖🧠
⬇️⬇️⬇️⬇️

🔹 𝙈𝙚𝙣𝙞𝙣𝙜𝙞𝙤𝙢𝙖
•Benigno, de células aracnoideas.
•Masa dural, “en remolino” con cuerpos de psammoma.
•Crisis epilépticas, signos focales.
•Más común en adultos.

🔹 𝙎𝙘𝙝𝙬𝙖𝙣𝙣𝙤𝙢𝙖
•Células de Schwann, afecta VIII par (ángulo pontocerebeloso).
•Hipoacusia, bilateral en NF2.
•S-100 positivo.

🔹 𝙊𝙡𝙞𝙜𝙤𝙙𝙚𝙣𝙙𝙧𝙤𝙜𝙡𝙞𝙤𝙢𝙖
•Maligno, frontal.
•Cefalea, crisis.
•Calcificaciones; células “huevo frito”.

🔹 𝙂𝙡𝙞𝙤𝙗𝙡𝙖𝙨𝙩𝙤𝙢𝙖 𝙢𝙪𝙡𝙩𝙞𝙛𝙤𝙧𝙢𝙚 (𝙂𝙧𝙖𝙙𝙤 𝙄𝙑)
•Más frecuente maligno en adultos.
•Necrosis con pseudopalisado, cruza cuerpo calloso (“alas de mariposa”).
•GFAP positivo.

🔹 𝘾𝙧𝙖𝙣𝙞𝙤𝙛𝙖𝙧𝙞𝙣𝙜𝙞𝙤𝙢𝙖
•Restos de bolsa de Rathke, supraselar.
•Hemianopsia bitemporal, calcificaciones “dentales”.
•Niños o adultos jóvenes.

🔹 𝙈𝙚𝙙𝙪𝙡𝙤𝙗𝙡𝙖𝙨𝙩𝙤𝙢𝙖
•Maligno cerebeloso (vermis).
•Ataxia, “células azules pequeñas”, rosetas Homer-Wright.
•Diseminación por LCR (“drop mets”).

🔹 𝙀𝙥𝙚𝙣𝙙𝙞𝙢𝙤𝙢𝙖
•En 4º ventrículo → hidrocefalia.
•Pseudorrosetas perivasculares.

🔹 𝘼𝙨𝙩𝙧𝙤𝙘𝙞𝙩𝙤𝙢𝙖 𝙥𝙞𝙡𝙤𝙘𝙞́𝙩𝙞𝙘𝙤
•Grado bajo, niños.
•Lesión quística con nódulo mural.
•Fibras de Rosenthal.
•GFAP positivo.

👇🏼👇🏼👇🏼👇🏼
📚📖#ClubCrit 👉 [https://t.co/kDo5QpqM9K]

#Tumor #Cerebro #LOE #NeuroX #ClubCrit #MedTwitter #CritCare #UCI #ICU #CriticalCare #Diagnóstico #icu #intensivecare #MedTwitter #diagnosis #management #Riesgo #ICU #POCUS #UCI #Tratamiento #MedicinaBasadaEnEvidencia #Emergencia #Terapia #MedEd #Medicina #Emergencias #FOAMed #FOAMcc #MedTwitter #CriticalCare #MedEd #CuidadoCrítico #MedX #IntensiveCare #EducaciónMédica #MedIntensiva #MedXCommunity #MedicinaCrítica #MedED #CritCare #ICUManagement #MustRead #LecturaRecomendada

[Dr. Rhonda Patrick @foundmyfitness]

Engaging in creative, skill-based activities like dance, music, visual arts, or gaming can reduce your brain's biological age by ~6 years.

Researchers measured the 'brain age gap' (the difference between predicted and actual brain age) and found that creative experts had significantly younger brains.

This expertise translates to greater neural connectivity in brain regions responsible for motor control, precise timing, mental imagery, and salience detection. They also had more efficient local and global neural networks, which is a signature of robust cognitive function.

Healthy brain aging isn't just about nutrition and exercise protocols. Deliberately challenging your brain with creative and skill-intensive pursuits profoundly enhances neural resilience and longevity.

[Catéter Doble Jota @cateterdoblej]

🧠📅 Hoy recordamos a Santiago Ramón y Cajal (1852–1934), padre de la neurociencia moderna.
Demostró que el cerebro está formado por neuronas individuales, no por una red continua, y sentó las bases de la neuroanatomía.
🏅 Nobel de Medicina 1906 (junto a Golgi).

[Neuron @NeuroCellPress]

Online now: Neurovascular dynamics in the spinal cord from development to pathophysiology https://t.co/ECbyPX2rSM

[Black Hole @konstructivizm]

This is how neurons form new connections in our brains
By RogueMonkeyyt

[Oscar Arias @OACerebro]

💤Redefiniendo el insomnio desde la neurociencia de sistemas.

El insomnio no es solo un trastorno del sueño, sino una alteración en la regulación del estado de alerta, caracterizada por:
🔹 Hiperactividad en redes de salida y control ejecutivo
🔹 Mayor excitabilidad cortical y desregulación emocional
🔹 Factores genéticos (MEIS1, CLOCK, PER2) y epigenéticos asociados al estrés temprano

El trabajo propone un cambio hacia modelos basados en mecanismos biológicos, integrando electroencefalografía, neuroimagen y aprendizaje autom��tico para identificar subtipos biológicos y diseñar tratamientos personalizados.

👉 https://t.co/jxdHy9QYGE
#Neurociencia #Sueño #Insomnio #Neurobiología #MedicinaDePrecisión

[Jun Nagai @JunNagaiLab]

Just out! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory https://t.co/po9zIlZvPb. New astrocyte tools are openly available at Addgene: https://t.co/OXCmcYSleI. 1/8