Juliana Xavier Ferrucio

[Juliana Xavier Ferrucio @FerrucioXavier]

So grateful to be part of this team!

[Diane Krause @Krauselab_Yale]

Congrats to J @FerrucioXavier, @VanessaScanlon, S. Halene, M Fleming, K Finberg and the rest of our amazing collaborative team!
#YaleHematology

[Diane Krause @Krauselab_Yale]

Thrilled to have our work on MEP fate in Fe def anemia out @BloodJournal. Big thanks to all on the team

Low Iron Promotes Megakaryocytic Commitment of Meg-Eryth Progenitors in Humans and Mice https://t.co/0HdkP5inRk
@YaleCCEH @Yale_LabMed

[Juliana Xavier Ferrucio @FerrucioXavier]

@AndreaFrizzo É amor que fala!! Obrigada Deia!!

[Juliana Xavier Ferrucio @FerrucioXavier]

Thanks Ahmad!

[Ahmad Al-Huniti @ahalhuniti]

Finally, I don't have to make things up to answer why platelet count is elevated in iron deficiency anemia #ASH2018

[Juliana Xavier Ferrucio @FerrucioXavier]

Thanks Naveen!

[Naveen Pemmaraju, MD @doctorpemm]

#ASH18 #P2 Dr Xavier-Furrucio | Fe def anemia and thrombocytis - why elevated plts in Fe def anemia ? For mechanism her team looked to megakaryocyte biology for the Answer. They found it ! Mech put forward via megakaryocyte commitment #MEP | @ASH_hematology

[Juliana Xavier Ferrucio @FerrucioXavier]

@TeamHaem Thanks!!

[TeamHaem @TeamHaem]

Why do you get high platelets with iron deficiency? Juliana Xavier-Ferrucio #ASH18

[. @IreneGhobrial]

We finally know why iron deficiency anemia leads to thrombocytosis #dfci #ash18

[Juliana Xavier Ferrucio @FerrucioXavier]

@IreneGhobrial Thanks Irene!!!

[Juliana Xavier Ferrucio @FerrucioXavier]

@DavidSteensma Thanks David!!

[Eric Tseng @tsengeric]

I have always wondered why iron deficiency is associated with theombocytosis #ASH18

Now we have our answer from mouse IRIDA models - low iron environment leads the mega-erythro progenitor MEP to bias towards megakaryocytic differentiation

[Juliana Xavier Ferrucio @FerrucioXavier]

@tsengeric Thanks Eric!!

[Matthew Cheung @MattCheungMD]

Why is iron deficiency associated with elevated platelets? Can’t wait for the answer at this year’s @ASH_hematology plenary. Impact of low iron on Mk-erythroid progenitor commitment is the #2 abstract and maybe a morning report game changer. #ASH18.    

https://t.co/Z2uY8PqAOY

[Juliana Xavier Ferrucio @FerrucioXavier]

@MattCheungMD @ASH_hematology @YaleMed Thanks Matthew!!

[Juliana Xavier Ferrucio @FerrucioXavier]

Thanks Jeff!!

[Diane Krause @Krauselab_Yale]

Thanks!!

[Juliana Xavier Ferrucio @FerrucioXavier]

@dskrausemdphd @Yalelab I’m so lucky to have the best mentors ❤️

[Juliana Xavier Ferrucio @FerrucioXavier]

Thanks Herve!!

[Diane Krause @Krauselab_Yale]

Thanks Herve!

[Kevin Kuo @CaptainAV]

Now that’s a beautiful presentation! We now know why iron deficiency cause thrombocytosis! Low iron affects MEP metabolism, leading to lower ERK phosphorylation, slower proliferation and promotes megarkaryocytic commitment. Xavier-Ferrucio J, et al. #ASH18 https://t.co/bxzbZD3fhx

[Juliana Xavier Ferrucio @FerrucioXavier]

I couldn’t be happier!

[Erick Lansigan @TheBloodMD]

I've always wondered why thrombocytosis occurs in IDA. I used to say it was reactive. Now we can say it is commitment. Thank you Dr. Xavier-Ferrucio! #ash18 #plenary