The Jagannathan Lab

Exploring the biology of repetitive satellite DNA.

[The Jagannathan Lab @FlyJagannathan]

Jagannathan Lab news - Part 1

A new paper from the lab jointly led by super students @flyhi_ankita and @Skrutlnize.

https://t.co/8CTNhovavU

We performed a multi-tissue proteomic screen using our favourite satellite DNA-binding proteins, D1 and Prod, as baits. (1/6)

[Michal Wieczorek @MikeVVieczorek]

Happy to share the first pre-print from the lab focusing on a closed conformation of the mammalian gamma-tubulin ring complex! https://t.co/ClZFneS1rJ

[The Rog Lab @TheRogLab]

Proud to have out this paper at @PNASNews from @LisaKursel and Jesus on the synaptonemal complex in C. elegans. It includes what is probably the most beautiful genetic data I was ever involved in analyzing - check it out! https://t.co/0GOPCjxDiM

[Jonathan Nelson @J0Nelson]

My lab's technician posting closes tomorrow. If have an interest in genetics, DNA repeats, germ cells, and how these relate to aging, there is still time to apply!

Learn more at https://t.co/dRfKrNUYrV

[Gabriel Neurohr @GabrielNeurohr]

@sandhya_manohar @MolecularCell @FEBSJournal This beautiful figure created by @sandhya_manohar illustrates nicley how hyperactive cell growth might sensitize cancer cells to CDK inhibitors as suggested by the recent findings the @DeRobertus @Alexis_Barr @_tonyly @AdeSaurin labs and our group

[Sandhya Manohar @sandhya_manohar]

Do you use cell cycle arresting drugs in your research?

Were you excited about recent papers on the relationship between cell size and senescence in @MolecularCell?

If you answered yes to either of these, check out our review in @FEBSJournal! 🧵(1/5)

https://t.co/R8knKpGW50

[ETH Zurich @ETH_en]

ETH Zurich researchers are illuminating what can happen when cells exceed their normal size and become senescent. Their new findings could help to optimise cancer treatments.

https://t.co/NqO2A3Q5NN

[Ankita Chavan @flyhi_ankita]

Lastly, a big shout out to the all the collaborators especially the @ericjoycelab, Randi Isenhart and @SonCNguyen, @Ranganlab, Noor Kotb, @kutay_lab, @federico_uliana, and all the authors for their contributions. Huge thanks to @FlyJagannathan for all the support and mentorship.

[Ankita Chavan @flyhi_ankita]

Are you curious about the proteins orchestrating nuclear architecture? Whether and how chromatin organization affects gene expression and cell fate? Check out our preprint showcasing recent work in collaboration with the @ericjoycelab and @RanganLab. https://t.co/n1NDmHVIec

[Gabriel Neurohr @GabrielNeurohr]

Can cell growth become a competitive disadvantage? We think yes – In the first paper from our lab (🎉) super postdoc @sandhya_manohar finds that excessive cell growth destabilizes the genome - a collaboration with @federico_uliana and @DeRobertus https://t.co/bhTwfjkuUc

[bioRxiv @biorxivpreprint]

A nuclear architecture screen in Drosophila identifies Stonewall as a link between chromatin position at the nuclear periphery and germline stem cell fate https://t.co/bR5eOc600V #bioRxiv

[bioRxiv Cell Biology @biorxiv_cellbio]

A nuclear architecture screen in Drosophila identifies Stonewall as a link between chromatin position at the nuclear periphery and ... https://t.co/Kb6u7WmFOZ #biorxiv_cellbio

[bioRxiv @biorxivpreprint]

Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesis https://t.co/mgFYdrs7Wo #bioRxiv

[Sandhya Manohar @sandhya_manohar]

Ever wonder why cells of the same type tend to have a pretty uniform size? Check out our new paper out in @MolecularCell today to find out why too big can be a bad thing in terms of genome homeostasis and proliferative potential. 🧵 (1/9)

https://t.co/OHRq0ls7P9

[Jonathan Nelson @J0Nelson]

I am hiring a research technician for my new lab at Stony Brook University!

The lab is new, but we share space with others, allowing to work directly with the PI (me) while having a great larger community in lab.

Please share!

https://t.co/vcWE6KhnrM

[Thor van Heesch @thorvanheesch]

Super excited to share together with @jocelyne_vreede and Peter Bolhuis my first research paper published in Nucleic Acids Research! We have developed a molecular simulation approach for predicting dissociation free energies of protein-DNA complexes:

[Leah Rosin (Lee-ah Rose-in) @scienceLeah]

We are NIH official 🎉

https://t.co/AA2THvvrJ6

[Takashi Akera @TakashiAkeraLab]

Our first research paper is now published at nature! 🎉🐭🔬We found that F1 hybrid female mice can have defective chromosome condensation in oocytes, creating a reproductive isolating barrier. Congrats again to our postdoc, Warif El Yakoubi🎊
https://t.co/olybynbVwQ

[Barral lab @LabBarral]

Our colleagues in the Kroschewski lab just published a new paper where they describe the 'exclusome' - a cytoplasmic container of extrachromosomal circular DNA. Congratulations to all the authors!

Here is a layman's version on the ETH website: https://t.co/KT850YyHth

[Claudia 🕊 Keller Valsecchi @KellerValsecchi]

🎉🎉🎉🎉🎉 The first research paper from our group is out 🦟🦟🦟🦟 I am soooooooooo HAPPY 😍 https://t.co/4hdIntz5Ll @imbmainz @Feli_Bas @agata_kalita

[IRB_Bellinzona @BellinzonaIrb]

PhD student position available in the @CejkaLab at the
@BellinzonaIrb

👉https://t.co/uifLuVFoJB

#irb #bellinzona #biosplus #phdstudent #phdstudentposition #application #cejka #recombinationmechanisms #DNA