Fox Lab at UD

Designing Reactions for Applications in Biology

[Fox Lab at UD @FoxGroupUD]

@TambarLab @UDelaware Excited to see this post and honored to be discussed in group meeting by the amazing Tambar lab!

[Fox Lab at UD @FoxGroupUD]

Congratulations to @Taylorlab_Chem and @kuehl_nicholas on another spectatular paper.

[Taylor Research Group @Taylorlab_Chem]

Our radical photocage work is out in @JACS! The photocage directly releases free CF3 radicals and enables MS-mapping of proteins w/ 1s rxns and prep-scale peptide trifluoromethylation in minutes. Impressive solo student author effort by @kuehl_nicholas! https://t.co/yhyoWrA2nM

[Taylor Research Group @Taylorlab_Chem]

Our radical photocage work is out in @JACS! The photocage directly releases free CF3 radicals and enables MS-mapping of proteins w/ 1s rxns and prep-scale peptide trifluoromethylation in minutes. Impressive solo student author effort by @kuehl_nicholas! https://t.co/yhyoWrA2nM

[Taylor Research Group @Taylorlab_Chem]

Check out our preprint in @ChemRxiv where we develop a photocage for biomolecular trifluoromethylation. Protein-interaction mapping w/ 1 second rxn times and prep scale labelling in 5-7 minutes. Impressive solo researcher effort by @kuehl_nicholas! https://t.co/5Yj5Npcr9a

[Fox Lab at UD @FoxGroupUD]

@ChrisamEnde1 @TallonAmanda Excited to see this story out in @J_A_C_S as the latest chapter in our collaboration with @Pfizer.  Led by
@TallonAmanda w/ Pfizer’s Mary Xu, Graham West & @ChrisamEnde1. https://t.co/PRIT5SaFIo

[Zondlo Lab @ZondloLab]

Awesome day yesterday with @aroralabnyu visiting! Great talk by and discussions with Bobby, as always. We made sure to give Bobby some local history at the Deer Park at the end of the day. In the Poe raven shadow. Quoth the @FoxGroupUD @CLGrimesLab nevermore!

[Fox Lab at UD @FoxGroupUD]

Thiomethyltetrazines are reversible covalent cysteine warheads whose reversibility can be "switched off” via live cell bioorthogonal chem, providing stability to lysis/proteomics. Led by @TallonAmanda w/ @Pfizer Mary Xu, Graham West & @ChrisamEnde1 10.26434/chemrxiv-2023-w0p5m

[Fox Lab at UD @FoxGroupUD]

Congratulations to Dr. Andrew "AJ" Jemas, most recent Ph.D. from the Fox group! You can check out one of his papers here: a collaboration with Pfizer to photocatalytically turn-on tetrazine ligation with subcellular precision. https://t.co/eDAcT9Mqns. So proud of you AJ.

[UD Research @UDResearch]

Congratulations to #UDel's Laure Kayser, who has won an @NSF CAREER award, supporting her research on a new class of #polymers using innovative chemistry and materials science approaches. https://t.co/c1qyZApZR7 @UDengineering @udcas #bioelectronics

[Fox Lab at UD @FoxGroupUD]

@MPWatsonLab @ChemistryUD Awesome! So well deserved!!

[Fox Lab at UD @FoxGroupUD]

https://t.co/JhRTudYPUk

[Fox Lab at UD @FoxGroupUD]

Out in @J_A_C_S! Ligand-directed catalysts for live-cell, photocatalytic activation of dihydrotetrazines coupled to new uncaging chemistry. Congratulations to Jules @RosenbergerJE, Yixin, Fang, Xinyi, Will and Olga! Thanks for support from NIGMS and
@Pfizer #PfizerChemistry

[Fox Lab at UD @FoxGroupUD]

Great to see this out in press. Congratulations Sam and Tyler!

[Angewandte Chemie @angew_chem]

Affinity Bioorthogonal Chemistry (ABC) Tags for Site-Selective Conjugation, On-Resin Protein-Protein Coupling, and Purification of Protein Conjugates (Fox) @FoxGroupUD https://t.co/WO563glC1v

[Fox Lab at UD @FoxGroupUD]

Still excited about bioorthogonal chemistry? Check out this preprint describing ligand-directed catalysts for live-cell, photocatalytic activation of dihydrotetrazine oxidation and uncaging chemistry. Kudos @RosenbergerJE, Yixin, Fang, Xinyi and Will! https://t.co/f2201Ionjb

[Fox Lab at UD @FoxGroupUD]

Joining the chorus of congratulations to this amazing trio and their research groups. Special shout out to @CarolynBertozzi and her alums who are blazing so many new trails that connect chemistry with biology and medicine.

[The Nobel Prize @NobelPrize]

BREAKING NEWS:
The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”

[Fox Lab at UD @FoxGroupUD]

@MPWatsonLab Thank you Mary!!!

[Fox Lab at UD @FoxGroupUD]

Congratulations to Julia Rosenberger @RosenbergerJE as one of the poster winners at the International Society of Heterocyclic Chemistry meeting. Thank you to @ishc1967, @thevanderwallab, and Javier and Yang at UCSB for leading a terrific meeting! Our group had a terrific time!

[Taylor Research Group @Taylorlab_Chem]

@Biochem_Chem Thanks @Biochem_Chem for the warm welcome! Very excited to be here @uarizona!

[Fox Lab at UD @FoxGroupUD]

Congratulations to an amazing colleague and scientist!

[Alexei Demchenko, PhD, ACSF @glycoworld]

As the @ACS_CARB Immediate Past Chair, I am happy to announce that Catherine Grimes @CLGrimesLab is a recipient of The 2023 Horace S. Isbell Award given for Excellence in and promise of continued quality of contribution to research in carbohydrate chemistry.

[Fox Lab at UD @FoxGroupUD]

@Taylorlab_Chem @Biochem_Chem @uarizona congratulations Mike and @Taylorlab_Chem on your many successes at Wyoming, and on your next adventure at @uarizona