Our radical photocage work is out in @JACS! The photocage directly releases free CF3 radicals and enables MS-mapping of proteins w/ 1s rxns and prep-scale peptide trifluoromethylation in minutes. Impressive solo student author effort by @kuehl_nicholas! https://t.co/yhyoWrA2nM
Our radical photocage work is out in @JACS! The photocage directly releases free CF3 radicals and enables MS-mapping of proteins w/ 1s rxns and prep-scale peptide trifluoromethylation in minutes. Impressive solo student author effort by @kuehl_nicholas! https://t.co/yhyoWrA2nM
Check out our preprint in @ChemRxiv where we develop a photocage for biomolecular trifluoromethylation. Protein-interaction mapping w/ 1 second rxn times and prep scale labelling in 5-7 minutes. Impressive solo researcher effort by @kuehl_nicholas! https://t.co/5Yj5Npcr9a
Awesome day yesterday with @aroralabnyu visiting! Great talk by and discussions with Bobby, as always. We made sure to give Bobby some local history at the Deer Park at the end of the day. In the Poe raven shadow. Quoth the @FoxGroupUD@CLGrimesLab nevermore!
Thiomethyltetrazines are reversible covalent cysteine warheads whose reversibility can be "switched off” via live cell bioorthogonal chem, providing stability to lysis/proteomics. Led by @TallonAmanda w/ @Pfizer Mary Xu, Graham West & @ChrisamEnde1 10.26434/chemrxiv-2023-w0p5m
Congratulations to Dr. Andrew "AJ" Jemas, most recent Ph.D. from the Fox group! You can check out one of his papers here: a collaboration with Pfizer to photocatalytically turn-on tetrazine ligation with subcellular precision. https://t.co/eDAcT9Mqns. So proud of you AJ.
Congratulations to #UDel's Laure Kayser, who has won an @NSF CAREER award, supporting her research on a new class of #polymers using innovative chemistry and materials science approaches. https://t.co/c1qyZApZR7 @UDengineering @udcas #bioelectronics
Out in @J_A_C_S! Ligand-directed catalysts for live-cell, photocatalytic activation of dihydrotetrazines coupled to new uncaging chemistry. Congratulations to Jules @RosenbergerJE, Yixin, Fang, Xinyi, Will and Olga! Thanks for support from NIGMS and
@Pfizer#PfizerChemistry
Affinity Bioorthogonal Chemistry (ABC) Tags for Site-Selective Conjugation, On-Resin Protein-Protein Coupling, and Purification of Protein Conjugates (Fox) @FoxGroupUD https://t.co/WO563glC1v
Still excited about bioorthogonal chemistry? Check out this preprint describing ligand-directed catalysts for live-cell, photocatalytic activation of dihydrotetrazine oxidation and uncaging chemistry. Kudos @RosenbergerJE, Yixin, Fang, Xinyi and Will! https://t.co/f2201Ionjb
Joining the chorus of congratulations to this amazing trio and their research groups. Special shout out to @CarolynBertozzi and her alums who are blazing so many new trails that connect chemistry with biology and medicine.
BREAKING NEWS:
The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”
Congratulations to Julia Rosenberger @RosenbergerJE as one of the poster winners at the International Society of Heterocyclic Chemistry meeting. Thank you to @ishc1967, @thevanderwallab, and Javier and Yang at UCSB for leading a terrific meeting! Our group had a terrific time!
As the @ACS_CARB Immediate Past Chair, I am happy to announce that Catherine Grimes @CLGrimesLab is a recipient of The 2023 Horace S. Isbell Award given for Excellence in and promise of continued quality of contribution to research in carbohydrate chemistry.