Michael Fox

Neurology Prof and Neuroscientist focused on brain imaging and brain stimulation @harvardmed @brighamWomens @brain_circuits

[Andrew Zalesky @AndrewZalesky]

Structural vs functional connectivity-guided accelerated iTBS in MDD

SC-guided iTBS produced promising preliminary evidence of improved antidepressant response compared with 5-cm targeting, supporting sgACC-based connectivity-guided precision TMS

https://t.co/rbvVrZFSfZ

[BD² @BD2Discoveries]

🧠Great to see the BD² community at NYC Neuromodulation 2026—sharing ideas, connecting across the field, and bringing our neuromodulation teams together.

[Can SARICA @CANSARICA2]

What a fantastic weekend at 2026 #NYC #Neuromodulation #Conference, without a doubt one of the best neuromodulation conferences of the year!

It was a pleasure to attend with a wonderful team from @Brain_Circuits. Huge congratulations to @foxmdphd, @shansiddiqi, @PinesAndrew, @b_hollunder, Samantha Baldi, and @NaN_Value for their outstanding talks and insightful panel discussions.

It was also great to reunite with my former @UofTNeuroSurge researcher colleagues, Ghazaleh Darmani and @HamidRamezanpou, who both delivered excellent presentations. An especially exciting moment was seeing Ghazel receive the prestigious Zabara Foundation #EarlyCareerAward with #focusedultrasound research, an incredibly well-deserved recognition. Congratulations!

A big thank you to the entire @neuromodec organizing committee, especially @MaromBikson, @allisoncwaters, Elisa Kallioniemi, and Renée Hartig, for putting together such an outstanding meeting. I'm already looking forward to next conference!

[Matt Burke @MattBurkeMD]

Massive study published yesterday in @NatureHumBehav for anyone in the neuropsychiatry/mind-brain-behavior spaces

Direct in vivo evidence for how attention can modulate the immune system in ways that seem almost unbelievable

https://t.co/PKuVQXp7rg

[Amit Etkin @AmitEtkin]

Great summary of the recent PRIME-PRAXOL @NatureMedicine trial results showing profound anti-anhedonic activity of pramipexole.

[Foundation for the National Institutes of Health @FNIH_Org]

For years, depression has been diagnosed as a single disease based on symptoms – yet the underlying causes can��vary from person to person. FNIH is launching the first phase of a long-term study that will collect data across a broad set of measures to identify biomarkers and more clearly define depression subtypes. This will pave the way for more individualized care for the nearly 21 million U.S. adults who experience a major depressive episode each year. 

Learn more: https://t.co/uAqIaFmOv5

#PrecisionMedicine #MAP-D #BridgestoBreakthroughs #Depression #BiomarkerScience

[Brain @Brain1878]

Using disconnectome analyses in stroke patients with aphasia, Ito et al. find that distinct neural pathways underlie writing deficits in kana (phonograms) and kanji (morphograms). https://t.co/ToinPNPsA6

[Eric Topol @EricTopol]

The cancer-Alzheimer's paradox, an inverse correlation, with an unexplained mechanism
"The risk of Alzheimer’s disease in patients with cancer is significantly reduced, and the risk of cancer in patients with Alzheimer’s disease is halved."
https://t.co/JOI0agYsWq

[Michael Fox @foxmdphd]

@warmxue @shansiddiqi Possibly, or could be a delayed effect of the more targeted stim or that placebo effects dissipate leading to more separation over time.

[Michael Fox @foxmdphd]

Is brain circuit targeted TMS better at treating depression than scalp targeted TMS? New paper by Joe Taylor @Brain_Circuits out today in @JAMAPsych says yes!

Connectivity- vs Scalp-Based Targeting of Accelerated TMS for Depression https://t.co/F04CIP1y0q

[Shan Siddiqi @shansiddiqi.bsky.social @shansiddiqi]

Thanks @Martijn_Figee_, @HelenMaybergMD, and Barak for a thoughtful editorial!

[Shan Siddiqi @shansiddiqi.bsky.social @shansiddiqi]

We all thought this study would fail, for different reasons.

Joe Taylor (1st author) thought it'd be a takedown of fMRI-guided TMS.

@foxmdphd and I (co-senior authors) thought the effect would be too small to detect in just 40 patients.

We were wrong.

https://t.co/MlFghE9hBX

[Rodrigo Braga @RodBraga]

Please RT - We are looking for someone who wants to establish and lead a cutting-edge neuroimaging center at Northwestern, working closely with multiple labs, including my own, in neuroscience research broadly construed.

If you are curious, dm me and Im happy to answer questions

[Amit Etkin @AmitEtkin]

A paper was just published in @NatureMedicine showing again the striking efficacy of pramipexole, the active component in ALTO-207, in a randomized trial of depressed patients with high anhedonia ! Congrats to Daniel Lindqvist, Filip Ventorp et al. A 🧵 https://t.co/9aG0d3J1mj

[UCSF Neurosurgery @NeurosurgUCSF]

New in @NatureMedicine, @DorisWangLab shows that distinct left- and right-leg swing biomarkers can drive DBS that changes on a sub-second timescale with each step. A major advance toward movement-driven, precision-timed neuromodulation for #Parkinsons. https://t.co/MiOTIyiw3Y

[Nico Dosenbach @ndosenbach]

We've known that socioeconomics (SES) matters for the 🧠. New & 🤯 is that SES drowns out all other brain associations, incl. IQ. If you train an algorithm to predict IQ from brain data, it's still way better at predicting SES. Science Magazine: https://t.co/YDplPlNJ5o
👀🧵👇

[JAMA Psychiatry @JAMAPsych]

In Denmark, average genetic risk among individuals diagnosed with #ADHD or #AutismSpectrumDisorder declined over two decades, supporting broadening diagnostic criteria as the main driver of rising rates.

https://t.co/X9II4SErqS

[Thomas Yeo @bttyeo]

Our TMS algorithm is now published in @ImagingNeurosci https://t.co/0hFtA7NOH1

If you are coming to @OHBM @OHBM_Trainees, come check out our poster about our open label trial.

Poster number 1152
Monday, Jun 15 | 14:45-15:45
Tuesday, Jun 16 | 13:30-14:30

[Nico Dosenbach @ndosenbach]

@souljagoyteller https://t.co/YDplPlNJ5o … IQ can’t be found in the brain after correcting for SES.

[Michael Fox @foxmdphd]

Can lesion network mapping predict survival in children with brain tumors? Collaboration with UCL and @Brain_Circuits in @Nature suggests the answer is yes. Cutting the tumor off from this network may confer survival benefit.
https://t.co/CiVAfkLiIv