Ghulam Ali Hasnan

Registrar @NottmHospitals #Gastroenterology #Aspirant_AdvancedEndoscopy

[Ghulam Ali Hasnan @GA_Hasnan]

Finishing BSG26 with multiple posters and and oral presentation. Great to connect with wonderful @rehan_haidry.
Thanks to @AamirSaeedMD for being awsome mentor.
@NHSGrampian @DrGrays_Elgin @nottmhospitals @BSGTrainees @BritSocGastro @ScotSocGastro
#BSGLIVE26 #BSG26 #GITwitter

[Ghulam Ali Hasnan @GA_Hasnan]

Save the date and time !!
Presenting our paper at #BSGLIVE26 . Huge thanks to wonderful Mentor @AamirSaeedMD
@NHSGrampian @nottmhospitals @BritSocGastro @BSGTrainees @DrGrays_Elgin @NEndoscopy @FrontGastro_BMJ @ScotSocGastro

#BSGLIVE26 #GITwitter #gastro #BSG #liverpool

[Ghulam Ali Hasnan @GA_Hasnan]

@BSGTrainees @BritSocGastro
#GITwitter

[Keith Siau @drkeithsiau]

A reminder that in the HALT-IT trial, tranexamic acid did not ⬇️ mortality or bleeding events, but ⬆️ venous thromboembolic events (x2️⃣).

Please stop giving TXA for GI bleeding. Doesn’t matter if it’s upper or lower 🩸- doesn’t work but can cause harm ⛔️

https://t.co/DNWhjzEfWd

[Ghulam Ali Hasnan @GA_Hasnan]

@BSGTrainees @BritSocGastro
#Gastroenterology

[Keith Siau @drkeithsiau]

A reminder that in the HALT-IT trial, tranexamic acid did not ⬇️ mortality or bleeding events, but ⬆️ venous thromboembolic events (x2️⃣).

Please stop giving TXA for GI bleeding. Doesn’t matter if it’s upper or lower 🩸- doesn’t work but can cause harm ⛔️

https://t.co/DNWhjzEfWd

[Aamir Saeed, MD @AamirSaeedMD]

Please check out our latest review published in @OfficeAme

Gastric per-oral endoscopic myotomy for gastroparesis – new review out now in Annals of Laparoscopic and Endoscopic Surgery

We synthesize the evidence on G-POEM for refractory gastroparesis, including candidate selection, technique, outcomes, and where it fits in the management algorithm.​

Key points:​
👉This review extends the evidence through 2025, incorporating multicenter and randomized/sham-controlled data, procedure steps with videos

👉Near-universal technical success with meaningful symptom and gastric emptying improvement in appropriately selected patients.​

👉EndoFLIP is a promising adjunct for selection and confirmation of adequate myotomy, but standardized thresholds are still lacking.​

👉G-POEM appears comparable to surgical pyloroplasty in efficacy, with shorter procedures and length of stay; cost-effectiveness and long-term durability need further study.​

@MRadlinski @AnthonyGamboa @PatrickYachimski
@sairayousuf059

#GITwitter #MedTwitter #Endoscopy #Gastroparesis #GPOEM

Link : https://t.co/IK2UUjxok9

[Ghulam Ali Hasnan @GA_Hasnan]

New Publication. @DrGrays_Elgin @NHSGrampian @nottmhospitals
#BSG

[Aamir Saeed, MD @AamirSaeedMD]

🚀🚨‼️New Publication alert

Excited to share our latest publication in @DDS_Journal, Prophylactic clip closure to prevent delayed bleeding after EMR in proximal large nonpedunculated colorectal polyps.

Key findings,

✅ 5 total RCTs with total 1604 patients

👉 Overall results did not show significant reduction in clinically significant Post EMR bleeding (CSPEB) after clipping.

👉However subgroup analysis of RCTs conducted at specialized/tertiary care/high volume settings showed significant reduction of CSPEB after clipping.

👉 RCTs conducted at community/mixed settings also did not show reduction in CSPEB after clipping.

Very grateful to @DouglasAdlerMD @DrFkamal @MRadlinski @MahamHayatMD @Nauzer Forbes @ Mansour Parsi and to all coauthors.
@ESGE_news
@ASGEendoscopy
@EndoCollabcom
@uthsc
@UTHSCResearch
#GITwitter
#MedTwitter

https://t.co/mryiXpsbpT

[Ghulam Ali Hasnan @GA_Hasnan]

@AamirSaeedMD @SLEPTonline @sairayousuf059 🥳👏🎊

[Aamir Saeed, MD @AamirSaeedMD]

Please check out our recent publication in @SLEPTonline Ballon assisted ESD (double balloon interventional platform) vs conventional ESD in colorectal lesions.

✅ 8 studies with 1449 total patients.

👉 There was no statistically significant difference in en bloc, R0 resection, adverse events and mean procedure time between the groups.

However subgroup analysis of RCTs only showed shorter procedure time with Balloon assisted ESD.

Very grateful to @DrFkamal @MRadlinski @SultanMahmoodMD @yasixiao @drKumarGI @SchlachtermanMD and to all coauthors.
@UPMC
@uthsc
@UTHSCResearch
@VUMChealth
#GITwitter
#MedTwitter

https://t.co/kFNSA7Li4u

[Ghulam Ali Hasnan @GA_Hasnan]

Acute Variceal Bleed Management.
#GITwitter

[Dr Aditya Gudheniya @Gastronaut___]

Few Key Points on Management of Acute Variceal Bleed (APASL 2025)

•Time-Zero (T0) redefined : T0 = time of first hematemesis, not hospital arrival, to capture the entire pre-hospital course.
•AVB episode duration = 48 hours from T0 (not 5 days as in Baveno VII). Any bleed within these 48 h = same episode.

•“Home-to-Door” time :- ideally 2 hours (acceptable up to 4h in mild cases). Delay >4–6h increases mortality.

•CT scan recommended as a non-invasive diagnostic tool to assess esophageal varices; CECT superior to LSM/MRI for high-risk varices.

•Pre-ER (ambulance) management :- Terlipressin 2 mg bolus can be administered during transport in suspected AVB.

•ER: Start vasoactive agent early : terlipressin/somatostatin/octreotide within 30 min of index bleed (“door-to-needle” time).

•All vasoconstrictors have comparable efficacy in initial control of variceal bleeding. Choice based on availability and comorbidities.

•Prefer terlipressin in AKI :- physiologic benefit and better renal outcomes.

•Continuous terlipressin infusion (4 mg/24h) preferred over intermittent bolus :- higher success, lower dose, fewer complications.

•Tranexamic acid :- may reduce post-EVL ulcer bleeding but does not reduce mortality and carries risk of portal vein thrombosis.

•After endoscopic control, vasoactive drugs may be stopped after 48 h, and NSBB started thereafter.

•Antibiotics : Ceftriaxone preferred; duration can be shortened to 2 days if endoscopic hemostasis is successful (vs 5 days).

•If both EV and GV present, obliterate gastric varices first even if no stigmata of recent bleed on GV.

•Gastric varices bleed less often but more severely; can bleed even when HVPG <12 mmHg due to large blood flow causing rapid and profuse bleeding.

•Key TIPS points :-
•Rescue option for failure to control bleeding.
•Consider early TIPS in high-risk patients (hemodynamic and endoscopic predictors).
•Preferred rescue therapy for refractory GV or PHG bleeding when endoscopic or radiologic options fail.

•Antibiotics are not recommended for acute variceal bleed in non-cirrhotic portal hypertension :- no evidence available.

#GITwitter

[Ghulam Ali Hasnan @GA_Hasnan]

@drkeithsiau Would it be a diagnosis of exclusion ? Would be consider commone things first like Crohn's etc first ?

[Ghulam Ali Hasnan @GA_Hasnan]

Excellent work Dr Saeed. Super proud of being part of your team. @AamirSaeedMD #ACG2025

[Sultan Mahmood MD FASGE @SultanMahmoodMD]

Congratulations to the superstar GI fellow @AamirSaeedMD on receiving the Outstanding Research Award in the Colon category at the @AmCollegeGastro!
Truly proud of your accomplishments — keep up the amazing work and continue to inspire! 👏🌟

[Ghulam Ali Hasnan @GA_Hasnan]

Presenting Poster at #ACG2025.
Such a great experience to learn and develop with wonderful mentors. @AamirSaeedMD @Marjan_Haider
@DrGrays_Elgin @NHSGrampian @ScotSocGastro @BritSocGastro
#GITwitter

[Carl Kay, MD @CarlKayMD]

Treat-to-Target in ASUC
▪️Day 0: Confirm dx, start IV steroids
▪️Day 3: Check stool freq + CRP
 ✅ Continue ❌ Rescue tx (IFX/CsA)
▪️Day 5–7:
 ✅ Maint. biologic ❌ Surgery
▪️Wk 8–12: Clinical remission
▪️Mo 3–6: Mucosal healing
▪️Ongoing: Steroid-free, QoL↑

#ACG2025 @ibdtweets

[Ghulam Ali Hasnan @GA_Hasnan]

Acute Severe Ulcerative Colitis management-take home.
#ACG #Phoenix @AmCollegeGastro @BritSocGastro @ScotSocGastro

[Ghulam Ali Hasnan @GA_Hasnan]

Over-Trusting FiT.
#IDA #Anemia #BSG #GIguidelines #CancerPathway #NHSgrampian @NHSGrampian

[Frontline Gastro @FrontGastro_BMJ]

⚠️ Are we over-trusting FIT in iron deficiency anaemia?

The new BSG & ACPGBI guidance makes it clear:
• A negative FIT does not rule out GI cancer in IDA
• Upper GI malignancy risk remains significant
• Bidirectional endoscopy is still key
• FIT must not delay investigation in high-risk patients

🔓 Full guidance in Frontline Gastroenterology: https://t.co/5ScqPuy48E
#IDA #FIT #CancerPathways #GIguidelines #FGJournal

@bodgoddard @BritSocGastro @ACPGBI @RCGP @PhilSmithIsBack @OTavabie @dr_aditi_kumar @TrevorTabone @eathar_s @IrenePerezMD @KGananandan @zare_benjamin @medicalreg @dtleiberman @BASLedu @BSGtrainees @WorldGastroOrg @ulstergastro @SEEDendoscopia @AmCollegeGastro @Aegastro @SAGES_updates @UHSEndoscopy @WAGE_media

[Ghulam Ali Hasnan @GA_Hasnan]

Presenting poster selected for presidential award at ACG 2025 conference. @NHSGrampian @DrGrays_Elgin @BritSocGastro @ScotSocGastro @AamirSaeedMD @jawthrust @AmCollegeGastro #Gastroenterology #ACG

[Ghulam Ali Hasnan @GA_Hasnan]

Presenting Poster at @rcpsglasgow Glasgow Gastro Conference. @NHSGrampian @DrGrays_Elgin @ScotSocGastro
#glasgowgastroconference

[Royal College of Physicians & Surgeons of Glasgow @rcpsglasgow]

Many thanks to everyone who joined Glasgow Gastro Conference today. Thanks also to all our speakers, session chairs and sponsors. Here are a few highlights from the day.

[Ghulam Ali Hasnan @GA_Hasnan]

Digestive Disease Week @TG_NHSCharity
#DDW2025 #ddw

[Ghulam Ali Hasnan @GA_Hasnan]

#DDW2025 #NHSGrampian