So proud of 3 MD/PhD students from @MayoClinicSOM & @MayoGradSchool who graduated yesterday. Sahej and her PhD work on #gene#therapy for #LQTS & Ramin and his work on #HCM over these past 6+ years has been so appreciated. And Jake (far left) is married to one of my scientists 🤗
Strong work @MCastrichiniMD and
big thanks to the nearly 1,500 genotype-positive ACM/DCM patients/families in our @MayoClinicCV@MayoClinicWSRGH Genetic Cardiomyopathy registry who made this and exciting ongoing work possible!
🔥 Thrilled to share our most recent study on the outcomes of VT ablation for LMNA Cardiomyopathy 🫀⚡️
📌 Despite ablation, rates of recurrent VT and death were remarkably elevated.
🙏🏽 Huge thanks to the team @MCastrichiniMD@VizentinVanessa@JohnGiudicessi@MJAckermanMDPhD
Big shootout to Dr. Reid Schlesinger an @MayoMN_IMRES resident for his work on the potential role of variant type in ventricular arrhythmias in RBM20-related cardiomyopathy that was published simultaneously in @JACCJournals during AHA! https://t.co/RV9SoyMx03
🚨PKP2-ACM patients show a distinct recovery-phase arrhythmic profile on EST—predictive of major ventricular arrhythmias.
Read more 👉https://t.co/z4qHrq4wI0
@MayoCVFellows@MayoClinicCV#CardioTwitter#EPeeps
Excited and grateful to share our paper describing how KCTD10 detects collisions between replication and transcription. Huge thanks to my mentors, collaborators, and reviewers who made this possible! @Nature@MayoClinic
https://t.co/fN3VVdnDha
PKP2-ACM is associated with a distinct ventricular arrhythmia pattern on exercise stress test that may carry prognostic significance. Strong work in @JACCJournals from @MayoClinicCV fellow @MCastrichiniMD and the @MayoClinicWSRGH team! https://t.co/XtgGxGxJAo
🚨 New @CircAHA#ESC2025#SimPub alert!
🚨 HCM isn’t just driven by rare Mendelian mutations. This study highlights the role of intermediate-effect variants (IEVs)—variants with moderate effect & low penetrance—in shaping disease expression. #HCM
https://t.co/uEqW1ZmrDb
RBM20 cardiomyopathy carries a more significant burden at a younger age, and an accelerated course compared to TTN cardiomyopathy
https://t.co/C2807uJKO1
#CardioTwitter
Glad to see our @JAMANetworkOpen study out. The study brings attention to the growing healthspan-lifespan gap across the world and reveals the largest gap in the US. The study documents a larger healthspan-lifespan gap in women associated with a disease burden disparity.
Happy to see our manuscript characterizing sex-specific differences in the multi-omics profile of HCM officially published! Grateful to @MJAckermanMDPhD and my co-authors for making this possible. https://t.co/MNfMpeFnqI
.@MayoClinic research is investigating the health effects of space travel on private citizens. A @MayoProceedings@ArminGarmany paper shares findings of the health response of the first all-civilian astronaut mission to the International Space Station.
https://t.co/xaAWthEDBs