Darren N. Nesbeth

Engineering Biology for Industrial Scale-Up

[茂木健一郎 @kenichiromogi]

東京大学共創ラボオープン作戦会議　池上高志　茂木健一郎　第２回　スケール仮説とデータ生成 @alltbl　

２０２６年５月２６日 #茂木健一郎 #脳の教養チャンネル #東京大学共創ラボ

[Georgia Channing @cgeorgiaw]

today was a massive day for protein engineering.

esmfold2 dropped—next gen of the esm series, fully open on @huggingscience. 1.1 billion predicted structures, 6.8 billion sequences. 800m more entries than the alphafold db, and reportedly edging out alphafold3 on protein complexes, including antibody–antigen binding.

alongside it: the new esm atlas. a huge expansion of known protein space, heavy on metagenomic sequences from soil, ocean, and the parts of biology that have been least characterised (until now!!)

and if that weren't enough, litefold dropped the fineweb of proteins, so every major protein database (pdb included) aggregated, cleaned, and made plug-and-play in one place.

these are the releases that push the whole field forward, and the pace of open science right now is almost motion-sickness inducing

all of it on https://t.co/T4l4r1lDz0 (and ofc @huggingface)

[Aunt Babe @babesmithh]

This is how you incorporate music into a scene the right way

[AFC Bournemouth 🍒 @afcbournemouth]

Entering the @premierleague record books 📚

Junior Kroupi, take a bow 💫

[Darren N. Nesbeth @GenePlumber]

The UCL Master’s Bursary
https://t.co/63Enm5wejl

[Darren N. Nesbeth @GenePlumber]

RIP J Craig Venter 😥

[Curiosity @CuriosityonX]

This single-celled protozoan passing though another one under a microscope

[Kenneth Loi @kenjmloi]

Adaptive immunity may have begun not as a bacterial invention. Ancient phages likely used VIPR-like systems against rivals. Bacteria acquired one, coupled it to a Cas1-like integrase, and transformed viral conflict into heritable immune memory.

[Michelle Lee @michellearning]

Welcome to the scientific revolution. 100s of robots. Zero coffee breaks. America’s largest autonomous lab, open today.

[Martin Codyre @martincodyre]

This is the best video I’ve seen to show how many different types of robots competed in the Beijing half marathon. cool to see all the different styles, etc. Easy to anthropomorphize these things.

[NASA Artemis @NASAArtemis]

Earthshine.

Artemis II astronaut Christina Koch captured this video of Earth outside the windows of the Orion spacecraft during the second flight day of the mission. Orion was roughly 33,800 miles (54,500 km) away from Earth when @Astro_Christina took this video.

[Reid Wiseman @astro_reid]

Only one chance in this lifetime…

Like watching sunset at the beach from the most foreign seat in the cosmos, I couldn’t resist a cell phone video of Earthset. You can hear the shutter on the Nikon as @Astro_Christina is hammering away on 3-shot brackets and capturing those exceptional Earthset photos through the 400mm lens. @AstroVicGlover was in window 3 watching with @Astro_Jeremy next to him.

I could barely see the Moon through the docking hatch window but the iPhone was the perfect size to catch the view…this is uncropped, uncut with 8x zoom which is quite comparable to the view of the human eye. Enjoy.

[Paul Bronks @SlenderSherbet]

Friends: "You should take up jogging, it's good for your mental health"

Me:

[Kyle Chan @kyleichan]

This Chinese humanoid robot just shattered the world record for a half marathon, finishing in 50 min 26 sec.

This video shows its crash just meters before the finish line where it had to be picked up by a team of humans. The robot is from Honor, the smartphone maker and Huawei spin-off. This robot was teleoperated while others were autonomous. It seems like all the robots had battery swaps along the way.

[Aviation @xAviation]

This pigeon was definitely not expecting the plane to accelerate that fast!

[Dudes Posting Their W’s @DudespostingWs]

Possibly the best unboxing video on the internet

[Financial Times @FT]

Europe and China are launching a joint space mission to study how Earth’s magnetic field shields the planet from harmful solar radiation, a rare example of collaboration as space competition intensifies.

Read the full story here: https://t.co/Wixg0Dj3Wa

[bayes @bayeslord]

well said

“[…] sanitize the air the same way we sanitize our water! but i also think biosecurity discourse can often have a pascal's mugging vibe to them, where the unboundedness of the downside is unfalsifiable by construction. i think being scared of scary things is a good thing (and bioterrorism is a very scary thing!), but infinite fear probably does not produce better prioritization than finite fear with a clear theory of change”

[NASA @NASA]

One last look at Earth before we reach the Moon.

This view of the Earth was captured on April 5, the fourth day of the Artemis II mission, from inside the Orion spacecraft. The four astronauts will reach their closest approach of the Moon tomorrow, April 6.

[Lucid™ @cammakingminds]

If you are using the earth as a reference frame, the moon is actually doing a close flyby of Artemis II.