Giessen Lab

Structure, function, and engineering of protein assemblies @UMich. Microbial Biochemistry | Cryo-EM | SynBio | Encapsulins | Natural Products | Enzyme Filaments

[Rezwan Siddiquee @RezwanSidd]

Nature has a trick to evolve multimeric proteins via gene duplication.
🧬One copy compensates, the other explores.🧬
Although this has only been a theory so far.
Until now: Directed evolution of multimeric proteins by dual-compensatory gene duplication.
https://t.co/sbrHAZxpJQ

[Giessen Lab @GiessenLab]

New paper out @NatureComms. Tremendous work by postdoc Mike Andreas, congrats! https://t.co/XyMj5lThtH

[Giessen Lab @GiessenLab]

New review out @ChemBioChem. Learn all about encapsulin shells! https://t.co/pOhhwl9KAR

[Giessen Lab @GiessenLab]

New paper out at @acsnano. Awesome work by PhD student Seokmu Kwon (@smkwon6) and postdoc Mike Andreas! https://t.co/Kdi02jrFQy

[Giessen Lab @GiessenLab]

Recent paper out at Protein Science (@ProteinSociety). Congrats to now graduated PhD student Robert Benisch (@robertbe_)! https://t.co/8iVFOoxiEx

[Giessen Lab @GiessenLab]

New preprint out @biorxivpreprint. Great work by PhD student Seokmu Kwon (@smkwon6) and postdoc Mike Andreas. Congrats!
https://t.co/RqpdsLPsfp

[Giessen Lab @GiessenLab]

New preprint out @biorxivpreprint. First two-component encapsulin system. Incredibly complex assembly. Congrats to PhD student Cassie Dutcher and postdoc Mike Andreas!
https://t.co/ToJM6sXKGN

[Giessen Lab @GiessenLab]

New preprint out @biorxivpreprint. First structure of a Family 2B encapsulin. Congrats to postdoc Mike Andreas!
https://t.co/IFEXlpid2o

[Giessen Lab @GiessenLab]

New paper out @NatureComms. Congrats to postdoc Mike Andreas, great work!
https://t.co/dXBobHvDQf

[Giessen Lab @GiessenLab]

New paper out @NatureComms. Congrats to postdocs Jesse Jones (now faculty at Idaho State) and Mike Andreas!
https://t.co/w3wtRC3Juw

[Giessen Lab @GiessenLab]

New publication from the lab. Congrats to PhD student @robertbe_ and postdoc Mike Andreas. Great work!
https://t.co/cVntiJJXVd

[Giessen Lab @GiessenLab]

Postdoctoral Research Fellow positions in cryo-EM | microbial biochemistry | protein engineering | natural product sciences available in our lab!

[Michael Cianfrocco @mcianfro]

1/ We’re excited to share our work on HIV-1 trafficking by dynein! Led by the amazing @badieyan in the lab with wonderful collaborations with @EdcampbellLab, @GiessenLab, Aiken Lab, Böcking Lab, and @morgan_desantis. TL;DR HIV-1 hijacks the dynein motor protein for motility 🧵

[Giessen Lab @GiessenLab]

Happy to have this paper published in @ACSSynBio
https://t.co/1lHlV3daB9
Congrats to my student @smkwon6

[Phyllis Hanson @PIHanson]

Come join our faculty @UMich in beautiful Ann Arbor!

Learn more and apply at https://t.co/tNnwYgo6S1

[Giessen Lab @GiessenLab]

New preprint is out on @biorxivpreprint:
https://t.co/JA4SozUfIJ
We characterize a highly acid-stable and dynamic encapsulin nanocage exhibiting pH-dependent all 'open' or all 'closed' pore states.
#encapsulin #nanocage

[Giessen Lab @GiessenLab]

New preprint is out on @biorxivpreprint:
https://t.co/o2ebWyQBr6
We engineer novel nanocages to package RNA and protein in vivo at the same time for future drug co-delivery applications.
Congrats to my student @smkwon6
#RNA #drugdelivery #encapsulin #nanocage

[van Hest Lab @vanhest_lab]

Thanks to @GiessenLab and Prof Schiller @FRIAS_UFreiburg for the external examination

[Giessen Lab @GiessenLab]

Happy that our review on the structure, function, and basic biology of encapsulins is now available @AnnualReviews of Biochemistry:
https://t.co/MqMGkkeyax
#encapsulin #nanocompartment #stressresistance #naturalproducts

[Yu Heng Lau @YuHengLau]

Our study on pore structure and molecular flux into #encapsulin nanocompartments with @GiessenLab is now in shiny typeset format in @ScienceAdvances

https://t.co/BlOLZQcF70

Congrats @nurentasneem, Lachlan, Regi, @taylorszyszka and Eric @MyxXanthus from our lab, and... 🧵