Giunta Lab

Giunta Lab of Genome Evolution @ University of Rome Sapienza. We study human centromeres' tug-of-war between fast evolution & essential function. AIRC funded.

[Giunta Lab @GiuntaLab]

We have some BIG news! @Simona_Giunta has been awarded an ERC STARTING GRANT from the @ERC_Research for her project "CentroFUN". Full news here: https://t.co/UishBZRd8e
We are incredibly happy, grateful & ready to celebrate @SapienzaRoma today - all welcome! 🍾🥂🧬
#ERCStG #ERC

[Giunta Lab @GiuntaLab]

Arrived! ❤️

[Giunta Lab @GiuntaLab]

Giunta Lab on the go ➡️ heading to our first long-due lab retreat in 5 years from the start --- Excited! 😊

[Ben Carty @ben_carty93]

What is the molecular basis for maintaining centromere size and position? In a great collaboration with @NAltemose @GiuntaLab and @FachinettiLab labs, we investigate the long standing question of how heterochromatin maintains centromere size/position! https://t.co/I41gYDcL8B

[Eric Green @NHGRI_Director]

I am starting a new video series called WAY COOL GENOMICS! Join me as I showcase examples where genomics is used in a study that is important, impactful, – and just plain WAY COOL!

[Simona Giunta @Simona_Giunta]

ERC-funded positions now open❗️❕❗️
Join the @GiuntaLab to understand human DNA evolution through the study of satellite repeats 🧬🧫🔬
APPLY here:
https://t.co/8cUYCV8YET
Pls RT 🔄🗨️🙏

[Giunta Lab @GiuntaLab]

@Simona_Giunta @SapienzaRoma 📸 Photo evidence of 'sunny Rome' ☀️

[Giunta Lab @GiuntaLab]

@Simona_Giunta @SapienzaRoma 📸 #ERC #celebration

[GIIN @GenomeIINetwork]

Dear community, we are very happy to announce the next Giin webinar!! Don't miss it on Tuesday, April 9th, from 5PM Rome (11AM NYC), with Stephen Jackson @SPJacksonGroup and Simona Giunta @Simona_Giunta. Zoom link: https://t.co/V7xPTI4YNK

[Giunta Lab @GiuntaLab]

With >100 people connected for an outstanding January session, so happy to see the GiiN #GenomeIntegrityItalianNetwork growing strong! Join us *today* with 2 exceptional speakers @DiffleyLab & @DubranaLab + check out our forthcoming 2024 series🧬
@GenomeIINetwork
@Simona_Giunta

[Giunta Lab @GiuntaLab]

@Frances87274236 @Ivarssonlab @NatalieKrahmer @maria_tanzer @signor_database @ChiaraFrancavi2 @charo_robles1 @chiara_dimalta @FrancesCryoEM @FrancescaNazio @CianfVale Grazie Francy 🧬🔬❤️

[Giunta Lab @GiuntaLab]

Thanks @Frances87274236 Here are 10 more awesome women in STEM:
@LabBallarino @yamashitaflylab @LugerLab @promiselcooper @khmiga @GrammaticoPaola @MaikoKitaoka @PasqualGiulia @neuroluci @TeresaDavoli3 pick it up and keep it moving!

[Francesca Sacco @Frances87274236]

Thanks @Ivarssonlab . Here are 10 more awesome women in STEM: @NatalieKrahmer @maria_tanzer @GiuntaLab @signor_database @ChiaraFrancavi2 @charo_robles1 @chiara_dimalta @FrancesCryoEM @FrancescaNazio @CianfVale pick it up and keep it moving!

[Ayantika Sen Gupta @notdatkndofdctr]

We have been needing this for a long time now. Thank you and congratulations @Simona_Giunta and team.

[bxv_genomics @bxv_genomics]

The complete human diploid reference genome of RPE-1 identifies the phased epigenetic landscapes from multi-omics data https://t.co/U2zptlfdav

[Giunta Lab @GiuntaLab]

LINK: https://t.co/iA8UE6nOWp
For early access to the complete RPE-1 assembly and any other enquiry, please contact us: https://t.co/6xWxzfCByv

[Giunta Lab @GiuntaLab]

What have we been doing since starting the lab in 2021? Assembling human genomes & studying their centromeres at basepair resolution. A new era of epigenomic is here! Check out our first work on preprint, constructive feedback wlecome 🧬🧫❣️NB.This work is supported by @AIRC_it

[Simona Giunta @Simona_Giunta]

🧬Complete Human Diploid Genome Alert❗️
So proud to share our first work as @GiuntaLab now on bioRvix - a monumental feat for a single lab assembling T2T RPE1 as a new reference to achieve epigenetic precision:
It's not just the length but how you use it!😊https://t.co/W3jT06z5wE

[Chromosoma_Edboard @Chromosoma_EB]

Chromosoma welcomes our newest Editor @Simona_Giunta at Uni-Rome/Sapienza. https://t.co/XvVAFsBqbl Simona brings deep centromere expertise with true Roman flair! Welcome Simona! -EIC

[Giunta Lab @GiuntaLab]

@Simona_Giunta sharing with the scientific community the new word she invented "isogenomic" and showing why that's important. Thanks to @nanopore for a fantastic #NanoporeConf - more great things to come, watch this space! 🧬🧫🤗

[Angelica Vittori @angelicavittor1]

DAJEE!!!!! @GiuntaLab !!!! @nanopore #LC23

[Angelica Vittori @angelicavittor1]

DAJEE!!!!! @GiuntaLab !!!! @nanopore #LC23

[Giunta Lab @GiuntaLab]

@angelicavittor1 @nanopore Thank you Ange + @nanopore for a fantastic #NanoporeConf - great for our lab to be invited + hearing @Simona_Giunta share with the scientific community the new word she invented "isogenomic" and showing why that's important 🧬❤️🧫 #LondonCalling2023

[Giunta Lab @GiuntaLab]

We brought together our data with those from too many labs to tag, and we propose the LAYERED LOOPING MODEL of #centromere #DNA organization to favor CENP-A positioning toward the kinetochore-microtubule binding interface. We are excited to showcase this & welcome feedback!🧵4/4

[Giunta Lab @GiuntaLab]

2015: @Simona_Giunta first imaged human centromere DNA after CenCOFISH in @HironoriFunabi1 Lab @RockefellerUni
2018-21: Presented at conferences the peculiar centromere ring structures
2021-23: Elena in the @GiuntaLab finally made the project blossom https://t.co/QkkJSPjdje🧵1/4

[Giunta Lab @GiuntaLab]

We found that the ring-like organization of alpha-satellite DNA at the mitotic centromere is present also under tension, even past metaphase. Pavan in @HironoriFunabi1 Lab showed CENP-A follows a similar organization by #ExM https://t.co/QkkJSPjdje🧵3/4