Lenhard group

We are a computational group based in the @MRC_LMS at Imperial College London @imperialcollege. Our research revolves around computational genomics

[Sarvesh Nikumbh @sarveshnikumbh]

🥳🥳 SeqArchR is now available online in PLOS Comp Biol
https://t.co/UTfSwXDBHt
- Give the article a read
- Use seqArchR Bioconductor pkg
- Appreciate simple but powerful NMF
- Share feedback
- Spread the knowledge
🙂🙂
@BorisLenhard @GroupLenhard
@MRC_LMS @imperialcollege

[Lenhard group @GroupLenhard]

Join us for an exploration of multicellular life through the lens of gene regulation!

[Boris Lenhard @BorisLenhard]

Join us!

We are seeking a PhD student and a Postdoc for in-depth study into promoter architectures, evolution of regulatory elements, and enhancer-promoter compatibility.

Please get in touch and/or RT!

Postdoc: https://t.co/gswie54Mes

PhD student: https://t.co/EDK8XDBBbN

[Lenhard group @GroupLenhard]

DNA methylation and obesity --- do you expect an association between them?

Yes! See QT below

Impressive efforts by @CroBeaver with other joint first authors in this study led by William Scott, Genomics of Obesity group @MRCLMS

Huge congrats @CroBeaver @BorisLenhard

[Damir Baranašić @CroBeaver]

Exciting collaboration within @MRC_LMS, led by the Genomics of Obesity group with @GroupLenhard, and @BorisLenhard, reveals the role of DNA methylation in obesity and diabetes in a groundbreaking study in @NatureComms. Check it out: https://t.co/BHOS51gZEW #ObesityResearch 1/8 🧵

[Lenhard group @GroupLenhard]

#InternationalWomensDay
Great occasion to share this news

Many congratulations to our recently graduated PhD student, now Dr. Radina Georgieva
@radinagg

@BorisLenhard @GroupLenhard @MRC_LMS
@imperialcollege

[Boris Lenhard @BorisLenhard]

A new preprint from our group, describing a tool for clustering promoters based on they key architectural elements and putting it to work to study some nice examples of time-dependent differential use of promoter classes.

[Lenhard group @GroupLenhard]

Thank you to our former members who made this huge effort possible, one of the co-first authors @PiotrBalwierz and @FabioDorazio

[Lenhard group @GroupLenhard]

Check out the latest publication from our group in @NatureGenet titled "Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements"
https://t.co/JRKMawJ5WC

[Lenhard group @GroupLenhard]

With @BorisLenhard as one of the corresponding authors, and @CroBeaver as the first author!

[DANIO-CODE @daniocode]

The comprehensive atlas of developmental regulatory elements in zebrafish is published today in @NatureGenet https://t.co/CjhNki9yj3. In addition to the BioRxiv submission https://t.co/koMC0IW6fH in this paper we added further resources and results. (1/n)

[Damir Baranašić @CroBeaver]

I am happy and proud that our DANIO-CODE @daniocode paper is finally out in Nature Genetics @NatureGenet! I wish to say thank you to everyone who helped and supported our work up until now, with the hope we can continue to deliver in the future as well!
https://t.co/HRhwkmMnHd

[Lenhard group @GroupLenhard]

New preprint from our group! With the first developmental regulatory atlas in zebrafish, we found new classes of regulatory elements with distinct features in time and space! 🎉🎉🎉 @BorisLenhard @CroBeaver @PiotrBalwierz @tobizehnder @FabioDorazio
https://t.co/zcVl4JHgoA

[Boris Lenhard @BorisLenhard]

Our manuscript describing a software (R/Bioconductor) toolkit for studying extreme noncoding conservation is now on bioRxiv:
https://t.co/GrVs9VPQ8v @ge11232002 @dpolychr2

[Lenhard group @GroupLenhard]

Our latest manuscript, published in Bioinformatics, proposes a robust, threshold-free measure of non-coding sequence conservation. @BorisLenhard
https://t.co/LC23R1BdqW

[D.Polychronopoulos @dpolychr2]

Our review on Conserved non-coding elements published today in Nucleic Acids Research | Oxford Academic https://t.co/Rhb878EO8q

[Lenhard group @GroupLenhard]

@NAR_Open https://t.co/kPxGJPto6F

[D.Polychronopoulos @dpolychr2]

Our review on Conserved non-coding elements published today in Nucleic Acids Research | Oxford Academic https://t.co/Rhb878EO8q

[Nathan Harmston @npharmston]

Our manuscript on the relationship between CNEs and TADs is finally out ... https://t.co/UbgYeEFNRf with @liz__is @BorisLenhard

[Boris Lenhard @BorisLenhard]

A PhD student position in computational genomics at Imperial, jointly supervised by Matthias Merkenschlager and me: https://t.co/cm1zb9wKBA

[Aziz Khan @khanaziz84]

Hall was full while @BorisLenhard was talking about TADs and GRBs at #ISMBECCB17 #RegGen @iscb

[Lenhard group @GroupLenhard]

PhD position at our group at Imperial College London on https://t.co/GtRH3u8Tr8 https://t.co/bMQZOs9Aoy

[Boris Lenhard @BorisLenhard]

Reminder: postdoc position in computational genomics available in my group. Four days left to apply. https://t.co/R6GBfbJMSx