Large (18k patients) metanalysis evaluating the benefit of adding adjuvant anthracyclines to taxanes for EBC
No benefit with anthracyclines when administered sequentially after taxanes (vs higher dose taxanes)
Unexpected benefit with concomitant administration
Landmark day in kidney cancer history. Adjuvant pembrolizumab now FDA approved in RCC at high risk of relapse post nephrectomy. Game changer. Congrats @DrChoueiri @tompowles1 https://t.co/od86pAAzkM
Preliminary OS results of MonarchE in overall pop and in the pop where the drug is approved by FDA . MonarchE assessed efficacy of Abemaciclib , a CDK4/6 inh in pts with HR+/her2- eBChttps://www.annalsofoncology.org/article/S0923-7534(21)04551-8/fulltext#.YXxIy37LgUA.twitter
FDA approved atezolizumab (Tecentriq, Genentech) for adjuvant treatment following resection and platinum-based chemotherapy stage II-IIIA NSCLC with PD-L1 expression on ≥1% of tumor cells. FDA also approved VENTANA PD-L1 (SP263) Assay as a CDx.
#lcsm
https://t.co/iwxIvZaCcY
Today FDA approved abemaciclib with endocrine therapy for adjuvant treatment of high-risk HR+/HER2- breast cancer & Ki-67 score ≥20%, based on MONARCH-E. Also approved Ki-67 IHC MIB-1 (Dako Omnis) assay. 1st adjuvant CDK 4/6 inh approved. #bcsm@OncoAlert@asco FDA alert.
A pesar de los beneficios del screening en cancer persisten importantes disparidades por la menor aceptación de los exámenes de detección de entre las minorías raciales, étnicas, sexuales y de género y las poblaciones médicamente desatendidas https://t.co/aK2aPmnBlM
The 5 year OS wall has been broken by Ribo for pts with endocrine sensitive stage IV BC . A milestone in oncology. When I saw the data first time, it came to my mind the very low 5 y OS I was learning when I was student #ESMO21