Excited to share our preprint, now available online on BioRxiv! https://t.co/LjayTn0d6b. We uncovered the coupling of translation and secretion machineries at the #axonalER to promote local delivery of axonal transmembrane proteins (TMPs) to the plasma membrane.
4) We identified the ER-translation regulator HDLBP and the NRZ-SEC22B tethering complex associated with axonal ERES and involved in unconventional secretion. Local removal of axonal ERES components or depletion of these identified players causes defects in axon development.
[Please REPOST] My lab is opening up a Fully Funded Postdoc Position to study the fascinating subcellular biology of brain synapses using state-of-the-art subcellular techniques, deadline Aug 11th @dandrite@NordicEMBL@MolBiolAU@AIAS_dk: https://t.co/tjr7gVUviB
Please SHARE: we are looking for a postdoc @dandrite@NordicEMBL@PromemoAU@MolBiolAU to study the impact of toxic proteins on synaptic molecular homeostasis. Deadline: Jan 31st, 2025.
https://t.co/UdzTLytCC5
So excited and grateful that @ERC_Research#ERCStG will fund my project https://t.co/uCbx8lUaXB to investigate the molecular mechanisms that regulate mRNA localization in neurons! There will be positions opening soon so get in touch if you are interested! @FGA_lab@VUamsterdam
Yesss!! It's out in @Dev_Cell!🥳Check it out to see lots of new exciting data on the axonal ER and local translation compared to the pre-print. Thanks to the reviewers for their insights that helped improve this study. And many thanks to all involved, a real team effort!
It's out!😭🕺First preprint as a PhD at the Farias Lab @ginny_farias where we investigated biosynthetic lysosomal membrane protein trafficking, delivery and interactome with Protein Origin, Trafficking And Targeting to Organelle Mapping (POTATOMap)🥔
https://t.co/vmiYfjIx7F
Happy to share our mini review in COCEBI written by @MaiDeeNguyen together with @ginny_farias and me. We highlight the exciting emerging role of contacts between the endoplasmic reticulum and membrane-less organelles in protein synthesis and secretion.
https://t.co/84YcVJnrln
We have a great program again with fantastic invited speakers for our annual Summer School on Neural Circuit Development and Plasticity in Utrecht/The Netherlands in July! 👇 Find more information on the website: https://t.co/3swUWYAe7G
I am recruiting! If you are looking for a PhD position and interested in molecular/cellular neuroscience, consider applying 👇RT appreciated! And happy holiday!
https://t.co/AelkaKzfG8
@amsterdamumc@AmsNeuroscience@GeneticAMS@FGA_lab@ERC_Research