So excited and grateful that @ERC_Research#ERCStG will fund my project https://t.co/uCbx8lUaXB to investigate the molecular mechanisms that regulate mRNA localization in neurons! There will be positions opening soon so get in touch if you are interested! @FGA_lab@VUamsterdam
📣 The latest ERC Starting Grant competition results are out! 📣
494 bright minds awarded €780 million to fund research ideas at the frontiers of science.
Find out who, where & why 👉 https://t.co/L6PimhW50v
🇪🇺 #EUfunded#FrontierResearch#ERCStG@HorizonEU@EUScienceInnov
APEX peroxidase is a versatile tool for proximity labeling and electron microscopy (EM) but its requirement for toxic H2O2 is a liability. We now report LaccID, a multicopper oxidase evolved from an ancestral fungal laccase that oxidizes aromatic substrates using non-toxic O2 instead of H2O2. We use LaccID for EM imaging of cultured cells and fly brains, and for proteomic mapping of the changing surface composition of T cells that engage with tumor cells via antigen-specific T cell receptors.
Beyond thrilled to present our O-MAP—now *published* @naturemethods (!!!)
O-MAP is a powerful new method for biochemically "dissecting" the subcellular microenvironment around an RNA of interest, using off-the-shelf parts and standard manipulations. 🧵
https://t.co/gBGsQ6dBs9
Neuromuscular dysfunction in patient-derived FUSR244RR-ALS iPSC model via axonal downregulation of neuromuscular junction proteins https://t.co/9LfIZkdG4H
Ataxin-2 polyglutamine expansions aberrantly sequester TDP-43 ribonucleoprotein condensates disrupting mRNA transport and local translation in neurons
https://t.co/n13bi6o2pE
Getting ready (rushing) for #SfN24?Us too!😃
Excited about Neuron, Glia, RNA, Plasticity, FXS or Local Translation?Us too!😃
Come join us Tues 8th, with 14 great (&short!) talks on emerging roles of axonal, dendritic, glial proteostasis in health & disease
pls spread the word!
We are hiring! If you are looking for a PhD position and are interested in cellular and molecular neuroscience, consider applying! @FGA_lab@VUamsterdam@ERC_Research Please share 🙏
https://t.co/aPRYKEnNGH
AXON2025 is gearing up! If you're passionate about neural circuit development, this is the must-attend event of next year — set in an extraordinary, non-conventional location🚢that you won’t want to miss! #AXON2025@JeroenPasterk
Conference in Grenoble 3th and 4th December 2024 "Organelles Transport in Health and Disease" --> Registrations are now open!! https://t.co/gQTO5rHL4C
So excited and grateful that @ERC_Research#ERCStG will fund my project https://t.co/uCbx8lUaXB to investigate the molecular mechanisms that regulate mRNA localization in neurons! There will be positions opening soon so get in touch if you are interested! @FGA_lab@VUamsterdam
📣 The latest ERC Starting Grant competition results are out! 📣
494 bright minds awarded €780 million to fund research ideas at the frontiers of science.
Find out who, where & why 👉 https://t.co/L6PimhW50v
🇪🇺 #EUfunded#FrontierResearch#ERCStG@HorizonEU@EUScienceInnov