Sandra Hake

Professor for Genetics interested in chromatin structure, histone variants and histone modifications.
Active account: @hake-chromatin.bsky.social

[Sandra Hake @Hake_Chromatin]

Please follow me on @hake-chromatin.bsky.social!

[Maria Christophorou @MAChristoLab]

Dear #Epigenetics Friends & Colleagues – Do YOU know where your histones are?

Our Xmas prezzie to the community (and perfect holiday reading): we went hunting for #histones and found them in all sorts of weird and wonderful places.

We report here 👇 https://t.co/sdYOXA30Wx

[Shilatifard Lab @ShilatifardLab]

My lab has been working for the past 15 years to develop a method to isolate specific genomic loci to identify its chromatin composition & protein interactome. Finally,… our superb physician/scientist Dr. Bercin Cenik @bkcenik did it and here it is https://t.co/f0vKe8pCFS Not only was she able to develop this method, which she calls TurboCAS, she was able to identify known & novel regulators of heat shock & Myc expression. Cannot wait to see what Bercin and TurboCAS will discover about the molecular basis of transcriptional regulation with great impact on clinic in the next few years! @NU_BMG_SQE @NUFeinbergMed @MolecularCell

[Sandra Hake @Hake_Chromatin]

We had an amazing X-Mas party with members of the Institute for Genetics! 🎄✨
Games, drinks, singing, and a lovely dinner. Many thanks to this incredible team of brilliant and caring scientists. Truly an honor to be part of this unique research family! ❤️

[Sandra Hake @Hake_Chromatin]

@maxi_prep @GfGenetik @tcgcambridge @CamVetSchool @sangerinstitute @emblebi @ResearchMenzies Congratulations!!!!! Fantastic work!

[Max Stammnitz @maxstammnitz.bsky.social @maxi_prep]

Deeply honoured to receive this year's Gateff Prize by the German Genetics Society @GfGenetik 🎓🧬

Recognition for an incredible team I had the privilege to work with during my PhD. @tcgcambridge @CamVetSchool @sangerinstitute @emblebi @ResearchMenzies

[Sandra Hake @Hake_Chromatin]

@AntoineMolaro @ERC_Research Wow, fantastic news! Congratulations! Well deserved.

[Sandra Hake @Hake_Chromatin]

@TheBraunLab @NAR_Open @SarahLa47195747 Congratulations, Sigurd and team!

[Patrick Cramer @mpgpresident]

Heute konnte ich an der Universität Gießen über die Entwicklung der globalen Forschung nach der US-Wahl sprechen. Danke für die Einladung!

[Sandra Hake @Hake_Chromatin]

@mpgpresident Es war schön dich wiederzusehen, Patrick!

Du hast eine sehr beeindruckende Rede gehalten, die nachdenklich machte, aber uns gleichzeitig auch inspiriert.

Vielen Dank für die tolle Arbeit, die du für uns WissenschaftlerInnen machst!

[Sarah Hainer @HainerLab]

Our new study, initiated by an undergraduate in the lab, was set to examine the effect of mutating histone H3.3 K122 to alanine. To do so, we attempted to generate murine ES cells mutating all four alleles, but were surprised when we couldn't generate these lines!

[Sandra Hake @Hake_Chromatin]

@OlallaLab @miomiomarco It was an honor working with you!!!! Thank you for your help!

[Sandra Hake @Hake_Chromatin]

@DocDellaire @NAR_Open @OlallaLab @JoelPMackay Thank you!

[Sandra Hake @Hake_Chromatin]

Excited to share our study on ZNF512B's role in binding NuRD, acting as a repressor, and facilitating DNA aggregation is now published in @NAR_Open!
Big thanks to our amazing collaborators @OlallaLab, @JoelPMackay, Marek Bartkuhn, & Falk Butter!
https://t.co/xCR08iKkrc

[Sandra Hake @Hake_Chromatin]

@OlallaLab @miomiomarco Congratulations!!!🎉🍾

[Mathieu Lupien @MatLupien]

📖 New review in Nature Reviews Cancer on how epigenomic heterogeneity drives tumour evolution! We dive into: Check it out if you're into epigenetics, single-cell tech, or the future of cancer therapy! 📖
https://t.co/WqJtxv1dH9

[Sandra Hake @Hake_Chromatin]

@OlallaLab @miomiomarco Thank you for this fantastic collaboration!

[Sandra Hake @Hake_Chromatin]

Exciting news! Our study on ZNF512B was accepted in @NAR_Open ! Huge congrats to the amazing PhD student and first author Tim Wunderlich and the entire team. Big thanks to all our collaborators! Stay tuned for more details after publication.

[Sandra Hake @Hake_Chromatin]

@LennartHilbert @KITKarlsruhe Congratulations!

[Sandra Hake @Hake_Chromatin]

@segal_eran Stay safe!