Popel Systems Biology Lab

Popel Systems Biology Lab at @JohnsHopkins @JHUBME @HopkinsMedicine @HopkinsEngineer. Computational Systems Biology, QSP, Angiogenesis, Cancer Immunotherapy

[Popel Systems Biology Lab @HopkinsPopelLab]

Virtual patient analysis identifies strategies to improve the performance of predictive biomarkers for PD-1 blockade | PNAS https://t.co/9UU0ZmLha8

[Popel Systems Biology Lab @HopkinsPopelLab]

@hopkinskimmel investigators develop computational tool to predict immunotherapy outcomes for patients with metastatic

[Microcirculatory Society @The_MCSociety]

We all enjoyed and were inspired by Shayn Peirce-Cottler’s talk! Congratulations on being the 2024 Eugene M. Landis Awardee! @PeirceLab #VascularBiology2024

[Esak (Isaac) Lee @IsaacLeeLab]

Just had an amazing dinner with my PhD advisor, Dr. Sasha Popel @HopkinsPopelLab @JHUBME. His exceptional mentoring has been instrumental in shaping the person I am today. Forever grateful for his guidance and wisdom!

[Joshua C. Doloff @DoloffLab]

Many congrats to @JGreenGroup on your installation as the Herschel L. Seder endowed Professor of @JHUBME!

[Shuming Zhang @zhangshuming199]

Really thankful to my mentors. Wouldn’t be possible without my awesome advisors @FertigLab @ltkagohara @HopkinsPopelLab

[Hanwen Wang @HanwenWang95]

From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling @HopkinsPopelLab
https://t.co/JdH5UB837b

[Popel Systems Biology Lab @HopkinsPopelLab]

Our latest modeling work integrates signaling and biophysical modeling to investigate how red blood cells are recognized and recycled in sickle cell disease, now in @PNASNexus. Thank you to our colleagues and collaborators at @jhubme @BrownUniversity @MIT https://t.co/IFnKyFBxa2

[PNAS Nexus @PNASNexus]

Watch a simulation of a macrophage engulfing an old, rigid red blood cell that needs to be recycled. The simulation was produced as part of a modeling study on macrophage dynamics that could help develop therapies for sickle cell disease. In PNAS Nexus: https://t.co/5HrdclpLGE

[Popel Systems Biology Lab @HopkinsPopelLab]

Congratulations!!!

[Dr. Stacey Finley (USC Systems Bio Lab) @USCSysBio_Lab]

after sharing the news with family and friends, i am thrilled to announce that i have been promoted to Professor of Biomedical Engineering and Quantitative and Computational Biology @USC !!
@USCViterbi @uscbme @qcb_usc

[Luciane T Kagohara 🇧🇷🧬👩🏻‍🔬👩🏻‍💻 @ltkagohara]

A few months ago, I posted about the @biorxivpreprint for spatial transcriptomics analysis of HCC. The paper is now published at @GenomeMedicine! 🎉🎉🎉
Many thanks to my collaborators for their amazing team work!!!
Open access through the link:
https://t.co/8cQ8B9uMma

[Shuming Zhang @zhangshuming199]

Huge thanks to team members in @HopkinsPopelLab and @FertigLab. Shout out to @ltkagohara and @atulpdeshpande for great mentorship! We are thrilled to see mathematical modeling spatial data from clinical trials coming together.

[Journal of Clinical Investigation @jclinicalinvest]

Macrophage–endothelial cell crosstalk orchestrates neutrophil recruitment in inflamed mucosa: https://t.co/SP4indJ7Sh
@SumaginLab @NUFeinbergMed
#CellBiology #Inflammation

[UVA COWIMS @UVACOWIMS]

This month, COWIMS highlights Dr. Shayn Peirce-Cottler for her brilliant work as Professor and Chair of Biomedical Engineering! Dr. Pierce-Cottler is also the PI of UVA’s Microvascular Engineering Lab. To learn more, visit https://t.co/R5s2x7AGmN. @PeirceLab

[Ibrahim Chamseddine, PhD @ibracham_]

A much needed call from @MathCancer to create a “Modeling Grammar.” A dictionary for hypothesis rules, modeling components, signals and processes will indeed facilitate reproducibility and communication across disciplines. Application to @PhysiCell was presented #SMB2023

[Popel Systems Biology Lab @HopkinsPopelLab]

Please see our latest work, just published on @ScienceAdvances: A transcriptome-informed QSP model of metastatic triple-negative breast cancer identifies predictive biomarkers for PD-1 inhibition
https://t.co/OUJzw9zPBj

[Hanwen Wang @HanwenWang95]

Generating immunogenomic data-guided virtual patients using a QSP model to predict response of advanced NSCLC to PD-L1 inhibition @HopkinsPopelLab
https://t.co/uWt3A71MSU

[Popel Systems Biology Lab @HopkinsPopelLab]

Congratulations to Theinmozhi Arulraj! Her amazing work on omics-informed #QSP model of #breastcancer metastasis has won the Oncology Session Award at the @ISOP1 QSP Student Symposium 2023!

[Popel Systems Biology Lab @HopkinsPopelLab]

Our review of systems biology models and omics of angiogenesis signaling published in @WIREs_Reviews is among the top downloaded papers!
Read on for more: https://t.co/jaatFkumky

[Popel Systems Biology Lab @HopkinsPopelLab]

We are thrilled to share our latest paper "Quantifying Intratumoral Heterogeneity and Immunoarchitecture Generated In-Silico …." published in @Cancers_MDPI. 📷

Read the paper: [https://t.co/x4G45V1G25] 📷

Congrats to the team and @mehdinik85 📷
#QSP #ABM #ITH #CancerStudies