Hugo Aerts

Professor @Harvard | Director, AI in Medicine (AIM) @MassGenBrigham I Professor @MaastrichtU.

[Hugo Aerts @HugoAerts]

Excited to share our new @TheLancet Perspective with @EricTopol .

For decades, the thymus was considered largely irrelevant after childhood. Emerging evidence now suggests this “forgotten organ” may play an important role throughout life.

[Hugo Aerts @HugoAerts]

@TheLancet @EricTopol A link to the paper can be found here: https://t.co/svHPDoEYId

[Hugo Aerts @HugoAerts]

Excited to share our new @TheLancet Perspective with @EricTopol .

For decades, the thymus was considered largely irrelevant after childhood. Emerging evidence now suggests this “forgotten organ” may play an important role throughout life.

[Hugo Aerts @HugoAerts]

Thank you, @EricTopol! It has been a true pleasure collaborating on this perspective. Amazing to see how rapidly our understanding of this long-overlooked organ is evolving, and how AI and imaging may help make immune system health measurable at scale.

[Eric Topol @EricTopol]

Challenging medical dogma, our understanding of the thymus and its impact on our health throughout lifespan has been completely revamped
w/ @HugoAerts @TheLancet
https://t.co/Wx4n7zeJwp

[Hugo Aerts @HugoAerts]

Grateful for the collaborations and support from:
@TheLancet
@scrippsresearch
@MassGenBrigham
@MGBResearchNews
@Harvard
@harvardmed
@MaastrichtUMC

[Eric Topol @EricTopol]

I wrote about this 6 weeks ago at Ground Truths when the 2 @Nature papers by @HugoAerts and colleagues came out. Today it's a "Health Alert"!
https://t.co/CgxBU7IAk1

[The ASCO Post @ASCOPost]

📊 New key findings on the thymus:
☑️ Better thymic health ➡️ lower cancer & cardiovascular mortality
☑️ Linked to improved immunotherapy outcomes
☑️ Influenced by lifestyle factors like smoking & obesity
👨‍⚕️ @HugoAerts of @MassGenBrigham | @Nature
🔗 https://t.co/68B7ihbfNs

[Eric Topol @EricTopol]

The medical dogma has been that the adult thymus is involuted, fatty tissue, and not functional. Was that ever wrong!
https://t.co/ENhIn2A2l3

[Eric Topol @EricTopol]

Don't take the time to read about the new landmark studies that put our thymus gland at center stage for healthy aging
https://t.co/ENhIn2A2l3

[Hugo Aerts @HugoAerts]

Loved this deep dive into our recent @Nature papers on thymic health. Insightful take and great breakdown of the key ideas. @EricTopol, thank you for taking the time to explore it in detail!

[Eric Topol @EricTopol]

Your Thymus and Your Healthspan
https://t.co/ENhIn2A2l3
High vs Low Thymic Health Scores and Outcomes

[Waggoner Lab @LabWaggoner]

Thymus health is a predictor of lifelong well-being and immunotherapy effectiveness @Nature @Simon_Bernatz @aim_harvard @nbirkbak @AarhusUni @HugoAerts
https://t.co/X6oj04omG3
https://t.co/eNO3PAZ0RX
https://t.co/cMHZnOuTm4

[Eric Topol @EricTopol]

Beyond all of this, in a 2nd @Nature paper by the same team thymus, health associated with improved response to cancer immunotherapy @HugoAerts @simonbernatz and colleagues https://t.co/qieD06nyOs

[Hugo Aerts @HugoAerts]

@EricTopol @Nature @simonbernatz Thank you for sharing this!

These two Nature papers were a true team effort. Thank you for noting these striking findings was how strongly thymic health relates to immunotherapy outcomes and longevity.
For more information, you can go here:
https://t.co/xiHUB5Wzis

[Hugo Aerts @HugoAerts]

Big news: the thymus may be critical for adult health

What if we missed something fundamental about the immune system?

In two back-to-back papers in Nature, we show thymic health (AI on 30,000+ CT scans) links to longevity, disease risk & immunotherapy outcomes.

[Hugo Aerts @HugoAerts]

👉 More to come - we’ll share deeper dives in the coming days

[Hugo Aerts @HugoAerts]

Big news: the thymus may be critical for adult health

What if we missed something fundamental about the immune system?

In two back-to-back papers in Nature, we show thymic health (AI on 30,000+ CT scans) links to longevity, disease risk & immunotherapy outcomes.

[Hugo Aerts @HugoAerts]

The second paper can be found here:
https://t.co/tYDHdaY9bW

[Hugo Aerts @HugoAerts]

Using AI on CT data from 30,000+ people, we found that the health of the thymus varies strongly between people – and is linked to longevity, disease risk, and response to immunotherapy.

[Mass General Brigham Research @MGBResearchNews]

Did you know your face can reveal your biological age?

Researchers at @MassGenBrigham developed FaceAge, an #AI algorithm that predicts biological age and survival outcomes for patients with cancer using a single photo. Patients with cancer appeared five years older than their actual age, and higher FaceAge predictions were linked to worse survival outcomes.

Read more: https://t.co/kIKdi5LYHr

#AI #CancerResearch #HealthTech

[Mass General Brigham @MassGenBrigham]

Did you know your face can reveal your biological age? @MGBResearchNews has developed FaceAge, an #AI algorithm that predicts biological age survival outcomes for patients with cancer using a single photo. Patients with cancer appeared five years older than their actual age, and higher FaceAge predictions were linked to worse survival outcomes. Learn more: https://t.co/eFTYtFvaXB

#CancerResearch #HealthTech

[Danielle Bitterman, MD @dbittermanmd]

Cross-Care is our new #LLM benchmark for measuring safety/bias in the #healthcare domain. We find misalignments between real biomedical facts, pretraining data, and LLM knowledge representation. Read more (https://t.co/S5NRH4Ircq) and explore our website (https://t.co/DvRFPjX3E5)