Advocate for dignity, respect, sustainability, inclusion and lasting social change for all Otherly-Abled, Differently-Abled, Well-Abled & disabled communities.
Alzheimer’s isn’t caused by bad genes.
It’s metabolic damage that slowly shrinks your brain.
It begins 20 years before doctors ever catch it.
Here’s the blueprint to protect your memory loss: 🧵
This is HUGE: Scientists have found a way to regenerate knee cartilage and prevent arthritis.
A new study from Stanford Medicine shows that blocking an age linked protein called 15-hydroxyprostaglandin dehydrogenase (15-PGDH) can restore cartilage that normally wears away with aging.
In mice, inhibiting 15-PGDH reprogrammed existing cartilage cells (chondrocytes) into a more youthful, regenerative state. Cartilage thickness increased, joint structure improved, and inflammation dropped, without using stem cells.
The treatment also prevented osteoarthritis after ACL-like knee injuries. Injured mice given the inhibitor for about 4 weeks avoided the rapid cartilage breakdown seen in untreated animals, which typically developed arthritis within the same timeframe.
Importantly, when human knee cartilage samples from joint replacement patients were treated in the lab, researchers observed reduced cartilage degeneration gene activity and signs of renewed cartilage formation.
An oral version of the same 15-PGDH inhibitor is already in early clinical trials for age related muscle weakness, suggesting a potential path toward human therapies for joint degeneration in the future.
🔭 @NASAHubble recently imaged the largest protoplanetary disk ever seen — and it’s far more chaotic and turbulent than expected.
The findings mark a new milestone for Hubble and shed light on how planets may form in extreme environments >> https://t.co/p2biDE0u4L
O Christmas tree, o cosmic tree 🎄
Located about 2,500 light-years from Earth, NGC 2264 is a cluster of young stars between one and five million years old. The stars appear as blue and white lights surrounded by swirls of gas—the “pine needles” of the tree—with green representing light in the visible spectrum.
Learn more:https://t.co/srOrqOnBqe
Here’s why scientists say activating happiness in the brain has nothing to do with money, fame, or luck.
Neuroscience shows that happiness is driven less by external rewards and more by internal processes. The brain’s well being circuits are activated through behaviors that create meaning, connection, and a sense of progress, not status or possessions.
One key factor is engagement. When the brain is fully involved in an activity that feels purposeful, dopamine is released in a balanced way. This kind of dopamine supports satisfaction rather than short lived excitement.
Social connection also plays a major role. Acts of kindness, shared experiences, and feeling understood activate oxytocin and serotonin, chemicals tied to lasting emotional stability rather than temporary pleasure.
Another driver is agency. The brain responds positively when you feel in control of your choices and actions. Small wins, learning, and self directed goals strengthen neural pathways associated with confidence and contentment.
The takeaway is simple. Happiness is not found by chasing outcomes. It is built by practicing habits that consistently activate the brain’s natural well being systems, regardless of circumstances.
PATRICK SOON-SHIONG: “We have in our body a gene called p53 that actually prevents cancer from occurring.”
“Guess what COVID does? It knocks down p53.”
Were We All Deliberately Poisoned!?😧
Blindness was once considered permanent. Not anymore.
Scientists helped living eye cells grow new branches and reconnect with the brain. When those links came back, the eye and brain started talking again.
This discovery shows that losing vision may not always be permanent. The eyes could have a chance to heal, even after damage.
Source: ScienceDaily
This is the most detailed view of a humain brain to date. 🌌🧠
What you’re seeing is just one neuron, connected to 5,600 distinct nerve fibers.
It looks like a dense forest or a cosmic web, but this is actually a reconstruction from a mere cubic millimeter of brain tissue. It’s a humbling reminder of the sheer complexity buzzing inside our heads right now.
Bret Weinstein & Joe Rogan drop a civilization-shattering idea
"Evidence points to recurrent disaster cycles erasing advanced societies—then we rediscover everything.
200,000-year-old inscriptions in Americas? Dates keep pushing back.
Academics rage at the thought—too small-minded to face it.
We're squandering our spectacular opportunity over stupid games while real threats loom."
This ancient reset theory is gaining traction...
3:29 clip inside—mind-expanding.
🚨Scientists just reprogrammed leukemia to self-destruct – and it worked.
In a major breakthrough, scientists at Institut Pasteur have developed a therapy that forces leukemia cells to self-destruct—and alerts the immune system to wipe out the rest.
The team targeted malignant B-cell leukemia with a triple-drug combination that reprograms cancer cells to undergo necroptosis, a form of inflammatory cell death.
Unlike the silent shutdown of apoptosis, necroptosis creates an immune alarm, drawing in the body's defenses. Using real-time imaging, researchers watched immune cells swarm the cancer, leading to total tumor elimination in lab models.
The challenge was that B-cell cancers typically lack a key protein, MLKL, needed for necroptosis. But the team cleverly sidestepped this using three existing clinical drugs. Together, they bypassed the missing protein and reactivated necroptotic pathways. The result: not just tumor shrinkage, but complete disappearance in multiple preclinical models. While human trials are still to come, the findings hint at a new kind of cancer therapy—one that doesn’t just kill tumors, but trains the immune system to join the fight. And because the drugs are already approved, the road to real-world use could be much shorter.
Source: Le Cann, F., et al. (2025). Reprogramming RIPK3-induced cell death in malignant B cells promotes immune-mediated tumor control. Science Advances.
@UCBDisability Understood, but the world has shifted under the most extreme abelist discriminatory biased standards intended to continue "othering" & negatively impacting the disabled community under COVID. #UniteforLife & accelerate terminology for empowerment, inclusion and productive change.
@GovKathyHochul@GovKathyHochul The title should be changed from Chief Disability Officer to "Chief ABILITY Officer" for inclusivity, empowerment and more effective change. @WSJ
To make the New York dream a reality, we need to make New York inclusive & accessible for all.
That's why I'm proud to sign legislation creating the Office of the Chief Disability Officer — and I'm appointing Kimberly T. Hill as our first ever Chief Disability Officer.