Ian Coombs

Pharmacologist and electrophysiologist working at UCL

[Ian Coombs @IanDCoombs]

The n's justify the means

[Ian Coombs @IanDCoombs]

@Argos_Online Hi, your chatbot @ArgosHelpers is unable to help me, but refuses to admit this. Is there any way I can communicate with a human? I need to cancel an order pre-delivery, but I placed the order as a guest i.e. I don't have an account.

[Ian Coombs @IanDCoombs]

Excited to start my new role as Lecturer @uclnpp! Big plans for student-centered research next year 🐸. Kicking things off today with a lecture on sustainability in lab science @SustainableUCL. Let's go!
📷📷📷📷📷📷

[Ian Coombs @IanDCoombs]

3. Many thanks to all of the contributors. In particular it was a huge honour to share a stage with @keithmcarthur, @m_farrant, @igreger1, Katherine Roche, @GRIN_tx, @a_mctague, @KBGenesBrains, Jessica Martin, @biocns, @ACPenn6, @s_schorge.

[Ian Coombs @IanDCoombs]

1. @uclnpp had an inspiring day with @CureGrin on 2nd March @IOE_London, hosting their latest #MeetandGRI event. Over 100 patients, families and researchers gathered to exchange knowledge and drive forward research at the UK’s largest ever GRI disorder meeting!

[Ian Coombs @IanDCoombs]

2. An amazing group of families representing multiple GRI genes attended #GRIN1 #GRIN2A #GRIN2B #GRIA2 #GRIA4. Plans to launch a new UK-based charity #GRI-UK were announced – exciting times! Hopefully, the first of many regular UK events.

[Ian Coombs @IanDCoombs]

Sensational work on #GRIA3 Disorder by @AllanBayat, Berardo Rinaldi, Anders Kristensen and colleagues. An excellent blueprint for future studies on genetic diseases of the AMPA receptors.

[Allan Bayat, associated professor @AllanBayat]

1/3
Delighted to share our open-access paper on #GRIA3, an X-linked neurodevelopmental disorder.

Before this paper, females were considered healthy carriers & limited data was available on affected males. What we found, was pretty cool...👇
#Morbidgene
https://t.co/uCblXW1PN4

[EpiCARE @EpiCARE_ERN]

Live with @AllanBayat at #IEC2023, to talk about his call for patients with rare disorders in 4 genes : #GRIA1, #GRIA2, #GRIA3, #GRIA4 🧬🔎

Find out more: https://t.co/fIRHWMnpbO and share to help advance #epilepsyresearch!

#rareepilepsy #raredisease

[Ian Coombs @IanDCoombs]

@AllanBayat @IlaeWeb @IBESocialMedia @AledoNeuro @AleRossiNeuro @CNSdrughunter @ExcitedBrains @FiladelfiaGene1 @LalDennis @KetteValente @KatjaKobow @rkalviainen @a_mctague You have made me very, very thirsty...

[PNASNews @PNASNews]

#Methane is a potent greenhouse gas. A strain of bacteria has been found that eats methane even when it is present at relatively low concentrations. By 2050, the microbe could keep 240 million tons of methane out of the atmosphere. In PNAS: https://t.co/K11qb8CX6w

[Pepe Meme @pepe_fgm]

Archerfish Shooting water to catch the insect

[Ian Coombs @IanDCoombs]

Nice work - 20% is a lot of money

[Science girl @sciencegirl]

The way this snail bridges the gap

📹@pTeLaNOGHRtRPQ6

[Ian Coombs @IanDCoombs]

The final version of our latest paper is now available:
https://t.co/bdevA52CfS @eLife
We demonstrate a clear benefit of using NASPM intracellularly, rather than spermine, to identify the calcium-permeability of synaptic AMPARs - auxiliary subunits no longer confuse the issue.

[Ian Coombs @IanDCoombs]

Incredibly pleased, proud and honored to be awarded a GRI Patient Impact Award at the @CureGRIN conference 2023! What an amazing few days engaging with scientists, clinicians, families, and, of course, patients.

[UCL Neuroscience @uclnpp]

congrats to @IanDCoombs and the farrant/cull-candy lab in @uclnpp and @uclbiosciences for their paper in elife! they describe an improved functional approach to identify the presence of the important calcium-permeable form of AMPA-type glutamate receptor: https://t.co/j8fI0VywXX

[Ian Coombs @IanDCoombs]

@WholesomeMeme Palpatine

[Ian Coombs @IanDCoombs]

@WholesomeMeme Palpatine in cat form

[Ian Coombs @IanDCoombs]

Some New Year's resolutions can be found here!

A very nice piece from Imperial College's Grantham Institute about how we can all help the planet in 2023 and beyond.

https://t.co/VPP5XDQsUW

[Rikke S. Møller @FiladelfiaGene1]

Excellent talks on #GRINpathies by Natalia Julia and @stephane_auvin 👏👏

Natalia showed that L-Serine should be considered in #GRIN LOF disease, whereas Stephane showed that #Radiprodil is a promising treatment option for patients with #GRIN2B GOF disease‼️
#PrecisionMedicine