Pavel Nesmiianov, MD, PhD

Twitto, ergo sum

[Pavel Nesmiianov, MD, PhD @Immunolol]

@SergiyKyslytsya "Good morning"... It was like this for like a dozen years, they've just updated the summary.

[Pavel Nesmiianov, MD, PhD @Immunolol]

@Rudeus_geylang @tbailey1976 @krassenstein You're sure that all X users in your country know that?

[Pavel Nesmiianov, MD, PhD @Immunolol]

@krassenstein As long as he admits that those are actually Indian

[Pavel Nesmiianov, MD, PhD @Immunolol]

I wasn't the only one who got tired of plethora of T cell subpopulations. It’s time to bring some order to this mess.
https://t.co/vlLaXQ2tx3

[Pavel Nesmiianov, MD, PhD @Immunolol]

No sooner had we begun to enjoy the idea of the continuum model of hematopoiesis than the Cincinnati scientists brought us back to the classic hierarchical model

[Lee Grimes Lab @LeeGrimesLab]

Implications for Hematopoietic Models
Contrary to the idea of a smooth continuum, the findings support a hierarchical model where stable, discrete progenitor states serve as key regulatory nodes. These states are governed by specific gene regulatory architectures, providing a molecular basis for the stability and lineage bias observed in hematopoiesis.

[Pavel Nesmiianov, MD, PhD @Immunolol]

Because there's only one.

[Pavel Nesmiianov, MD, PhD @Immunolol]

@Jikkyleaks you accused company of faking data based on their use of more advanced technology...and yup, it's called "automated western blot", not "synthesised"...

[Pavel Nesmiianov, MD, PhD @Immunolol]

I'm all hands up for innovation, but enteric coating already does the job...

[Science Magazine @ScienceMagazine]

A new mineral coating described in @ScienceAdvances may help oral probiotics survive manufacturing and digestion. https://t.co/eRoZdCDCuJ

[Pavel Nesmiianov, MD, PhD @Immunolol]

@Jikkyleaks lol this is what happens when you don't catch up with modern technologies like Jess blot analysis.

[Pavel Nesmiianov, MD, PhD @Immunolol]

OK, that's what I do. A Christmas Run.
#raretweets #labroutine

[Pavel Nesmiianov, MD, PhD @Immunolol]

@JustinLathia This can't be the same guy I've met 10 years ago!

[Pavel Nesmiianov, MD, PhD @Immunolol]

More of a bad target, than a bad drug.
Read: Safety, tolerability, pharmacokinetics and (NONE OF) antitumor activity of #oleclumab Phase I trial.
https://t.co/3rnasnTbBE
#AstraZeneca

[Pavel Nesmiianov, MD, PhD @Immunolol]

Platelets are tiny, but it's all about good old Zerg Rush. RBCs are welcome to join! Read:
Platelet-derived TLT-1 promotes tumor progression by suppressing CD8 T cells https://t.co/N8DQWrTc02

[Pavel Nesmiianov, MD, PhD @Immunolol]

Those macrophages always been acting as public transport for the bad guys. Gotta get rid of 'em: "Subcapsular sinus macrophages promote melanoma metastasis to the sentinel lymph nodes via an IL-1α–STAT3 axis". https://t.co/XfQJNYpylF
#Immunology #melanoma #macrophages