@gonoise Very bad. Not accurate. Tracking me sleeping while I am awake. 😠 When I tried to file a complaint, the website was not working, and when I mailed multiple times, they said they only register complaints via their website. Big fraud. 😡 #inaccuracy#tracking#complaint#website
@gonoise Very bad. Not accurate. Tracking me sleeping while I am awake. 😠 When I tried to file a complaint, the website was not working, and when I mailed multiple times, they said they only register complaints via their website. Big fraud. 😡 #inaccuracy#tracking#complaint#website
@gonoise Very bad. Not accurate. Tracking me sleeping while I am awake. 😠 When I tried to file a complaint, the website was not working, and when I mailed multiple times, they said they only register complaints via their website. Big fraud. 😡 #inaccuracy#tracking#complaint#website
@ICICI_Direct Very bad. Not accurate. Tracking me sleeping while I am awake. 😠 When I tried to file a complaint, the website was not working, and when I mailed multiple times, they said they only register complaints via their website. Big fraud. 😡 #inaccuracy#tracking#complaint#website
@gonoise Very bad. Not accurate. Tracking me sleeping while I am awake. 😠 When I tried to file a complaint, the website was not working, and when I mailed multiple times, they said they only register complaints via their website. Big fraud. 😡 #inaccuracy#tracking#complaint#website
@gonoise Very bad. Not accurate. Tracking me sleeping while I am awake. 😠 When I tried to file a complaint, the website was not working, and when I mailed multiple times, they said they only register complaints via their website. Big fraud. 😡 #inaccuracy#tracking#complaint#website
Here's a global alert for everyone:
I just found a suspicious Pepsi bottle with heavy residue and floating particles inside definitely not safe to drink. If you spot any duplicate or contaminated soft drinks, report it immediately and keep the evidence. Let's stay alert
@pepsi
@Flipkart my issue is not resolved, and you are posting false information (As per our conversation, we are working to solve your issue.) But no one contacts me, and your team is also ending chats without listening to the customer, due to which my mental health is getting affected
Ordered a sofa from @Flipkart on Oct 6. Every time I ask for an update, I get the same copy-paste response, and the chat is often ended abruptly without solving the problem. Very disappointed with the poor support and lack of accountability. #CustomerService#OrderDelay
Ordered a sofa from @Flipkart on Oct 6. Every time I ask for an update, I get the same copy-paste response, and the chat is often ended abruptly without solving the problem. Very disappointed with the poor support and lack of accountability. #CustomerService#OrderDelay
@Truemedsindia It has been aprox 3 days showing same my order is delayed you your self increase delivery date. If there is any technical issue Kindly replace my order by your self and resolved that issue! 😠 #delayedorder#customerservice#delivery#issue
Insulin resistance can begin 10–15 years before the onset of prediabetes or diabetes
▶️Insulin resistance typically precedes prediabetes, which in turn precedes type 2 diabetes. This is a well-established progression that unfolds gradually, often over many years.
The Relationship:
Insulin Resistance (IR):
This is the earliest abnormality, where cells in muscles, fat, and liver become less responsive to insulin.
The pancreas compensates by secreting more insulin (hyperinsulinemia) to keep blood glucose normal.
Prediabetes:
As insulin resistance worsens, the pancreas can no longer keep up, and blood glucose levels start rising but not enough to meet the threshold for diabetes.
▶️This stage may show up as:
1. Impaired Fasting Glucose (IFG)
2. Impaired Glucose Tolerance (IGT)
3. HbA1c between 5.7–6.4%
Type 2 Diabetes Mellitus (T2DM):
Eventually, beta-cell dysfunction worsens, leading to persistently high blood glucose levels.
▶️Diagnostic thresholds:
1. Fasting plasma glucose ≥126 mg/dL
2. Two-hour post-load glucose ≥200 mg/dL
3. HbA1c ≥6.5%
✅Timeline:
1. Insulin resistance can begin 10–15 years before the onset of prediabetes or diabetes.
2. Prediabetes typically precedes T2DM by 3–10 years, depending on lifestyle, genetics, and intervention.
✅Conclusion
1. Insulin resistance is the earliest abnormality, but it is not routinely tested.
2. Among standard tests, post-prandial glucose abnormalities often appear before fasting glucose or HbA1c changes.
Clinical Tip:
1. For early detection in high-risk individuals:
Consider fasting insulin and HOMA-IR (Homeostatic Model Assessment of Insulin Resistance)
2. Do a 2-hour oral glucose tolerance test (OGTT) if prediabetes is suspected despite normal FBG and HbA1c
(Serum Triglyceride: HDL-Cholesterol ratio is a good surrogate marker for detecting insulin resistance.
A TG:HDL-C ratio > 3 indicates insulin resistance. Both TG and HDL-C are parts of lipid profile, which is routinely tested, making it a cost-effective method to detect insulin resistance).