Ismael Moreno Sánchez

Research Assistant at @crisprscan in @CABD_UPO_CSIC

[Ismael Moreno Sánchez @IsmaelMSanchez]

Thrilled to share that our new preprint is out on @biorxivpreprint! Enhanced RNA-targeting CRISPR-Cas technology in zebrafish performed at the Moreno-Mateos lab @crisprscan @CABD_UPO_CSIC. A thread (1/13): https://t.co/yEtS4cP043

[Instituto de Neurociencias UMH-CSIC @NeuroAlc]

A new study led by @NietoAngela lab at @NeuroAlc is out in @NatureComms🙌. Researchers show that cancer cells acquire metastatic potential while in the primary tumor, well before reaching distant organs.
More info 👇
https://t.co/IynKsgftml
(1/7)

[BazziniLab @BazziniLab]

🐟 We are hiring a postdoc!
Interested in RNA regulation, gene expression, and zebrafish embryogenesis? Join the Bazzini Lab at @ScienceStowers
https://t.co/cipJOA4SFc
Please share! Details below 👇
#Postdoc #RNAbiology #zebrafish #devbio #Genomics

[Moreno-Mateos Lab @crisprscan]

Super happy that @Luisherhuertas work recently published in the EMBO Journal was awarded as best paper of the year in the @CABD_UPO_CSIC! A great way to end the year!

[SINC @agencia_sinc]

La revista @Nature ha presentado su 'top ten' de de personajes clave ciencia de 2025, desde grandes avances médicos hasta descubrimientos que amplían nuestro entendimiento del planeta y del cosmos.

https://t.co/tB8vADv6F1

[Centro Andaluz de Biología del Desarrollo @CABD_UPO_CSIC]

¡Enhorabuena al equipo responsable por el trabajo publicado en @embojournal que ha sido co-liderado por @BazziniLab de @ScienceStowers & @crisprscan del #CABD!!!

[Moreno-Mateos Lab @crisprscan]

Fenomenal nota de prensa de nuestra última contribución para entender un poco mejor los primeros eventos durante la embriogenesis. @Luisherhuertas @CABD_UPO_CSIC @bazzi https://t.co/AroeuQTt1m

[Luis Hernández-Huertas @Luisherhuertas]

Nota de prensa sobre nuestro último artículo publicado en @embojournal 🎉

Una fantástica colaboración entre @crisprscan y @BazziniLab

[Ismael Moreno Sánchez @IsmaelMSanchez]

Very proud to have participated in this amazing work published in @embojournal where we have described Bckdk as a post-translational regulator of MZT in teleosts 🐟 using our optimized CRISPR-RfxCas13d system.
Congrats @luisherhuertas, @crisprscan and all participants!! 🎉👏🏽

[Luis Hernández-Huertas @Luisherhuertas]

✨ Happy to share that our work is now published in @embojournal! ✨

Our fantastic collaboration between @crisprscan from @CABD_UPO_CSIC and @BazziniLab from @ScienceStowers. Take a look to our updated thread (1/14):

https://t.co/yDnav2CHKQ

[Moreno-Mateos Lab @crisprscan]

Still open to get applications for this postdoctoral position. Please send me the required information. Also, I will be in two weeks in Sorrento for the CRISPR-Cas workshop, so if you are around and would like to work in our lab, this would be a great opportunity to meet :)

[RosadoLab @RosadoLab]

El contrato para realizar tu tesis doctoral en inestabilidad genetica y procesos tumorales en Anemia de Fanconi ya esta disponible. Solicitala!! Please RT!

https://t.co/kXxcykO1Bj

[Moreno-Mateos Lab @crisprscan]

Glad to share that the website for the MZT EMBO workshop that I organize together with Ana Boskovic (EMBL, Rome), Antonio Giraldez (Yale U) and Melissa Harrison (U Wisconsin) is out: https://t.co/ewGlf67Yg8
Please spread the word and join us in beautiful Seville next 4-7 May!

[Ismael Moreno Sánchez @IsmaelMSanchez]

@AdMOSC_Research @CABD_UPO_CSIC @NatureComms @SpringerNature @crisprscan @Luisherhuertas @nahon_daniel Credits for @CieloCentola! Everyone loves that amazing cartoons!! Thanks again!! 🫶🏽

[Ismael Moreno Sánchez @IsmaelMSanchez]

Want to now more about our last paper in @NatureComms? 🚀
We expand & consolidate the RNA-targeting #CRISPRCas toolbox 🔬🧬
Read more in @SpringerNature communities 👇

https://t.co/5X7HE6w0nw

@crisprscan @CABD_UPO_CSIC @Luisherhuertas @nahon_daniel
#CRISPR #RNA #Biotechnology

[RosadoLab @RosadoLab]

Si estás interesa en hacer una tesis doctoral en tumorogenesis asociada a la inestabilidad genética, contáctanos!!!
Please RT!!

[Ismael Moreno Sánchez @IsmaelMSanchez]

Muy contento de haber liderado este trabajo junto con dos magníficos compañeros @Luisherhuertas @nahon_daniel en el Moreno-Mateos lab @crisprscan @CABD_UPO_CSIC. ¡Gracias a todos los compañeros y colaboradores por el gran trabajo!

[SINC @agencia_sinc]

El equipo del Centro Andaluz de Biología del Desarrollo @CABD_UPO_CSIC ha conseguido optimizar diferentes sistemas CRISPR-Cas in vivo usando el pez cebra como modelo

https://t.co/PUrMX7ytB4

[SINC @agencia_sinc]

El equipo del Centro Andaluz de Biología del Desarrollo @CABD_UPO_CSIC ha conseguido optimizar diferentes sistemas CRISPR-Cas in vivo usando el pez cebra como modelo

https://t.co/PUrMX7ytB4

[Moreno-Mateos Lab @crisprscan]

First seen in Biorxiv and now published and updated with more data in @NatureComms. With this work we have further enhanced CRISPR-Cas RNA targeting in vivo using transient approaches such as RNP or mRNA-gRNA in zebrafish embryos as vertebrate model. https://t.co/ISC61e6cog

[BazziniLab @BazziniLab]

Our last work is now in @biorxivpreprint. Great work of @gopalkushawah in collaboration with @BMRL_Danielson @huzaifahassan @mmarchin and @S_Nowotarski all done at @ScienceStowers @StowersGrad
https://t.co/w0kKXtoTOR

[Moreno-Mateos Lab @crisprscan]

It was a fantastic lab retreat with a lot fun, new ideas and great scientific discussions. Super proud of this excellent team we have built since 2019! And thanks to our invited colleagues @BalbontinLab @RosadoLab and Thirsa Brethouwer for their invaluable contribution!

[Ismael Moreno Sánchez @IsmaelMSanchez]

And, of course, thanks to the institutions that fund our lab! @pablodeolavide, @CSIC, @CienciaGob, @UniversidadAnd, @PpccSalud and @Synthego that awarded us with the Genome Engineer Innovation Grant some years ago (13/13)

[Ismael Moreno Sánchez @IsmaelMSanchez]

Forth, we demonstrated that collateral activity is triggered when transient CRISPR-RfxCas13d approaches target extremely abundant and ectopic mRNAs such as reporters, inducing non-targeted DsRed fluorescence decay, 28S rRNA fragmentation and developmental defects (8/13)

[Ismael Moreno Sánchez @IsmaelMSanchez]

@AdMOSC_Research from @IIQ_US_CSIC, A. J. Treichel, @GaPescador and @gopalkushawah from @BazziniLab @ScienceStowers, @JnGiS and @NietoAngela from @NeuroAlc, @KevinHoldenSF and J.A. Walker II from @Synthego (12/13)