Antonio Angelastro

Chemistry. Enzymology. Glycobiology. Biocatalysis. Biologics Engineering.

[Nature Synthesis @NatureSynthesis]

Now online & open access:

Article by @Isotope_Effect, @WillGoRow, @FlitschSabine & co-workers @UoMMIB

Horner–Wadsworth–Emmons olefination of proteins and glycoproteins

https://t.co/BtGa46f93a

[Christian Schnepel @Ch_Schnepel]

Fully funded 2-year postdoc position (starting date: Jan/Feb 2024) on biocatalysis, enzyme engineering, and reaction cascades available in my group. Please share.

https://t.co/YrDn0XM6NK

[TomKingChem @TomKingChem]

It's very exciting to see the pre-print of Laura's paper (Selective N-terminal modification of peptides and proteins using acyl phosphates) out now on @ChemRxiv. She's done some awesome work and it's great to have been part of it. Check it out at: https://t.co/U1QY3hmIpx

[RSC Protein and Peptide Science Group @RSC_PPSG]

Our Protein & Peptide Science Early Stage Researcher meeting will be held on 20th Oct 2023 at The Royal Society of Chemistry, Burlington House.

More details are here: https://t.co/CKTwi4d2rE

[M. Carmen Galan @MCGalan_Bristol]

@FlitschSabine discussing the power of biocatalysis in carbohydrate chemistry @EUROCARB21 . Superb masterclass!

[RSC Protein and Peptide Science Group @RSC_PPSG]

Stop scrolling 👀… and register (for free) for the next @RSC_PPSG lunchtime seminars on protein and peptide science. This Friday 2nd June at 1 pm UK time, we have informal research talks from Guto Rhys (Cardiff) & @drandybrennan

https://t.co/X3AokYvjgP

[Antonio Angelastro @Isotope_Effect]

@BiocatTUD Oh dear.

[Sebastian Cosgrove @scosgrove123]

Great work from @Jacksangster6 @Turner_Biocat here in @J_A_C_S. Chemoenzymatic synthesis of chrial cyclic amines with amine oxidases and allylboronates. Well done becky and @juanmangas both involved too!

https://t.co/nvpfQjqwgK

[Mike Waring @MikeJWaring]

2 days left to apply for the PhD studentships in our group with @MosmedC @NCL_MedChem @EvaristeTechno1 @ChemistryNCL

[Antonio Angelastro @Isotope_Effect]

@StephanHacker2 @ChemRxiv @FlitschSabine My wife, who is a traditional synthetic organic/medicinal chemist, is still recovering from the shock that you can indeed use HWE chemistry on an antibody.

[Yi Jin @JinGroupMIB]

Our work with @the100footpole @YuanHeNWU on explaining the biphasic kinetics of OXA-48-like carbapenemases caused by chloride is out.
"Discovery and molecular basis of chloride as an allosteric activator and catalytic inhibitor for Class-D lactamases" https://t.co/4qjcGDGu9B

[Antonio Angelastro @Isotope_Effect]

@fryania @gbernardes_chem This is what I thought when I first read this outstanding work, and I am sure you people will win this next challenge in due time. Congrats!

[Antonio Angelastro @Isotope_Effect]

After chairing the Biological Session III of @UoMChemistry postgraduate conference, I believe we shall have a bright future after all. @Baldwin_Chris_ @JessLlo32291290

[Juan Mangas @juanmangas]

Our review on chemoenzymatic cascades is under the "accepted articles" section at @EurJOC. Happy to be part of the #NextGenOrgChem special collection and congrats to Christian for his first contribution as the 1st author.@ARAID_ES @ISQCH_Divulga @AgEInves https://t.co/sbdLaBc1fC

[Stuart Conway @conway_group]

Looking forward to #ChemBioIreland in August. Excellent speakers including: Nediljko Budisa, @Cochrane_lab, @FlitschSabine, @PhosphorusFive, @klanglab, Andreas Marx, @J_McGouran, Eddie Myers, @rtraines, Helma Wennemers & Valentin Wittmann. #ChemBio https://t.co/DjkOh1BEVF

[Turner Biocatalysis @Turner_Biocat]

Our work with the @FlitschSabine group on Thioester Mediated Biocatalytic Amide Bond Synthesis with In Situ Thiol Recycling is available as a preprint!

Nice work by @Ch_Schnepel and Laura, with @YuqiYu7 @Isotope_Effect @RachelHeath82 @makslub and @AstraZeneca

[Yi Jin @JinGroupMIB]

A fully-funded international 3.5-yr PhD studentship available to join @JinGroupMIB at Uni of Manchester. Please spread the word! https://t.co/emsliSSe2p

[Beilstein-Institut @beilstein-institut.bsky.social @BeilsteinInst]

📅 April 14, 🕒 3–4 pm CEST – Register for 🆓 and join the ONLINE #BeilsteinTalk “Cascading #Biocatalysis” with Sabine Flitsch, @FlitschSabine @OfficialUoM.

🔗 https://t.co/H91oHna3kV
#BeilsteinTalks #OrganicSynthesis #Enzymes #Biocatalysis

[Turner Biocatalysis @Turner_Biocat]

We are excited to share that our
work on a multifunctional enzyme that catalyses conjugate reduction and reductive amination is out now in @nature! This was a collaboration with the Grogan group @YSBL, @Prozomix and @pfizer
https://t.co/8yj5ZGyOzf