Ania Fryszkowska

explorer, bionomad, into biocat, cats and bio

[Ania Fryszkowska @fryania]

Work at the forefront of sustainable innovation, driving impactful change in drug development. Apply if you’re passionate about applying cutting-edge science to real-world challenges
#Biocatalysis #ProteinEngineering #EnzymeEvolution #GreenChemistry #Microfluidics

[Ania Fryszkowska @fryania]

We’re hiring a Senior Scientist in Chemical Biotechnologies!

Join us in pushing the boundaries of biocatalysis, protein engineering, enzyme evolution, and microfluidics to solve challenging chemistry problems with biology
Apply here:

https://t.co/6Vml3gLXxA

[Ania Fryszkowska @fryania]

We’re looking for protein engineers, molecular biologists, and biocatlysis experts who are excited about leveraging enzymes and cutting-edge technologies for greener, more efficient pharmaceutical processes.

This New Jersey-based role

[Enzyme Chemistry @EnzymeChemistry]

Emergence of a distinct mechanism of C–N bond formation in #photoenzymes by Felix C. Raps @felix_raps, Ariadna Rivas-Souchet, Chey M. Jones @CheyMJones, and Todd K. Hyster @HysterLab at @PrincetonChem https://t.co/z5lOfovJrF

[Jue Wang @jueseph]

My team at Deepmind (protein design) is hiring an experimentalist with enzyme expertise. Please RT and/or apply! I'm happy to answer any questions as well. https://t.co/2acSQJX4At

[Ania Fryszkowska @fryania]

Amazing news for the world of #proteins, #enzymes , #chemistry and #biocatalysis! Great day for science!

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

[Ania Fryszkowska @fryania]

🍃🍃🍃🍃🍃

[Ania Fryszkowska @fryania]

Challenging oxidations? Oxygen-dependent #enzymes reduce our environmental impact. In our latest pre-print we share the process development of a scalable aerobic oxidation process leading to the aldehyde in the synthesis of islatravir. 🌱💊 https://t.co/2RC6ww5YL5

[Ania Fryszkowska @fryania]

Ever wondered what it takes to transform an enzymatic reaction on a small scale to a full-fledged industrial process? Our journey with nucleosides—Islatravir and Molnupiravir—has been a wild rollercoaster ride!
https://t.co/N5L6lRGdWG

[Organic Process Research & Development @OPRD_ACS]

Online today in #OPRD! ADC conjugation empowered by data-rich technologies, continuous flow and high-throughput experimentation, using tool molecule collections of non-toxic linker/payload mimics. #merckchemistry @emmertlab @cecibottecchia Read it here ⤵️ https://t.co/PJxdhlg4Ql

[Scott France @ScottFrance10]

Thoroughly enjoyed the 2024 #Biocatalysis #GRC! Great job @FlitschSabine and Carlos Martinez. Bring on the 2026 meeting with me and Dörte Rother as vice-chairs! Very excited to work with chairs @sBiosChem and Radka Snajdrova as well as GRS chairs @hairofthehogg and @MaxGantz_!

[Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social @RolandDunbrack]

Demis -- I think AlphaFold3 is really exciting. As Reviewer #3, I got great results from the server. I tried hard to get @Nature to urge you to release the code but was unsuccessful. I did not get it for re-review so I don't know if you responded. So why no code? @GoogleDeepMind

[Yang Yang @yang2biocat]

We publish our second paper on pyridoxal biocatalysis in Nature: We repurposed PLP-dependent threonine aldolases to catalyze radical C-C coupling reactions that are not known in either organic chemistry or enzymology: https://t.co/ZgagtQ56BK

[Ania Fryszkowska @fryania]

It's pretty sweet the team paid attention to the trace peak product in their control reaction and then rode with it! Luck is what happens when preparation meets opportunity.

[Ania Fryszkowska @fryania]

Self-recycling imine reductases? Yes please! Congrats to the Novartis team for turning a promiscuous Glucose Dehydrogenase into an IRED #biocatalysis #proteinengineering #greenchemistry | ACS Catalysis https://t.co/qkQvfPNfFC

[Ania Fryszkowska @fryania]

Big congrats to Serge for trailblazing the field and merging the modes of #catalysis for enabling complex redox and ligation reactions with electrons. Here is another great example of his work https://t.co/dbMVnOac8R

[Ania Fryszkowska @fryania]

Electrons ⚡ or oxygen🫧?Which of 🍃 green oxidants would you choose? Selected from an amazing list of nominations for his work on integrating #biocatalysis and electrochemistry, Serge Ruccolo from #Merck is the 2024 ACS Catalysis Lectureship Awardee! https://t.co/iOSuteyhhS

[Ania Fryszkowska @fryania]

A perfect way to start the weekend! our paper on Electrochemical Activation of Galactose Oxidase is out now! We have had great fun with @hattoriheji and @SergeBFault merging the modes of #catalysis https://t.co/BTlP65ZFLM #biocatalysis #electrocatalysis

[Institute for Protein Design @UWproteindesign]

Our latest AI tools for protein modeling & design were highlighted on the cover of @ScienceMagazine.

Read the open-access paper: https://t.co/27aTIxpRRk

Use these tools for free:
RoseTTAFold All-Atom: https://t.co/U0a6ea1E69
RFdiffusion All-Atom: https://t.co/jyWt267Dgf

[Dani Schultz @danithechemist]

We’re hiring in Discovery!! 💊🥼🧬

We have multiple openings in Boston, San Francisco and West Point (PA) spanning Bachelor's, Master’s, entry level PhD and PhD with experience. Go to https://t.co/qC9WxDMXzu and search for ‘Discovery Chemistry’ or ‘Peptide’!
#MerckChemistry

[Ania Fryszkowska @fryania]

Everything should be made as simple as possible, but no simpler. Also true for enzymes.
Latest work from @noahpdunham, @asymtmm and #Merckchemistry team on unlocking complex amino acids without directed evolution thanks to smart donor ...lysine #biocatalysis #thermodynamics

[Noah Dunham @NoahPDunham]

Lysine an amine donor in transaminase-catalyzed reactions?

A thrifty hack for driving equilibria!

https://t.co/bZ1LD4iMPh