Bini Ramachandran

Mass spectrometry/Proteomics nerd, who loves to travel and take photographs, but prefers to live in a virtual world.

[Bini Ramachandran @ItsBiniR]

As the critical analysis for whatever happened yesterday starts, the fundamental issue that many in America can't stand an assertive woman in a leading position will definitely be the point that won't get addressed..

[London Proteomics Discussion Group (LPDG) @LPDGproteomics]

Moving over to Bluesky. Please come and join us over there https://t.co/ghYeXSdqjj #teammassspec #proteomics

[Bini Ramachandran @ItsBiniR]

Hello @JProteomeRes, @J_ASMS, please come to the place where skies are blue.. #TeamMassSpec misses your updates..

[Magnus Palmblad @MagnusPalmblad]

A little spin-off from last week's @ELIXIREurope #BioHackathon: https://t.co/qJRXPoHWFr

[Alejandro Brenes @AJ_Brenes]

#teamMassSpec If you're in #proteomics or #mass spec and fancy starting or checking out the other place 🦋🟦 here is a good list to start you off, we're getting good representation there without the endless issues of this site.

Starter pack available: https://t.co/UqnmnKexsn

[Dr. Erin Baker @ErinBakerIMS]

Check out the 2024 Emerging Investigators Issue for @J_ASMS. The future of mass spectrometry is definitely in good hands!!
https://t.co/ibYG5KfjEv

[Bini Ramachandran @ItsBiniR]

@UCDProteomics @J_my_sci @neely615 Thanks very much, Brett for sharing this.. It's too awesome..

[Bini Ramachandran @ItsBiniR]

This is mind boggling!! The analogies it is drawing to explain the basic concepts of proteomics are exemplary.. May be this is the solution to those communication challenges came up in latest episode of #TheProteomicsShow.. Generative AI is awesome..

[Brett Phinney @UCDProteomics]

@J_my_sci @neely615 Getting this on YouTube so you don't need to login to listen to it was way more complex than it needed to be, but I did it :)
https://t.co/1WGR9MqC8S

[Retraction Watch @RetractionWatch]

We've joined Bluesky.
https://t.co/RAlJo1Wm4J

[Bini Ramachandran @ItsBiniR]

@dschweppe1 Well.. As a habit (or by obsession), I try to ensure e10 BPC intensity for every whole cell lysate TMT-MS3 runs.. Just a way of making sure on-column load is good.. 7e9 is indeed a good response.. And I promise I am not this Reviewer 2..

[Bini Ramachandran @ItsBiniR]

@neely615 @UCDProteomics @Wybenga_Groot Yayy.. Looking forward to #POTRH..

[Bini Ramachandran @ItsBiniR]

Spectra for 1536 single cells acquired over 40 SPD Slice-PASEF workflow.. ~40 days of acquisition!

Btw Bruker provides a spectra library?
'Analyses were performed using a library-based approach (spectral library provided by BRUKER containing 67686 proteins and 13827 genes)' 🤔

[Pastel BioScience @PastelBio]

High throughput single-cell proteomics of in-vivo cells https://t.co/UvkQvnO3xb

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#proteomics #prot-preprint

[Bini Ramachandran @ItsBiniR]

@funtoshs @UCDProteomics @ProteomicsNews Sorry, don't have any information on this..

[Bini Ramachandran @ItsBiniR]

@the_ion_doctor Congratulations to the PIs.. Looking forward to seeing publications from the new project..

[Bini Ramachandran @ItsBiniR]

2024 update from Human Plasma Proteome Project..#HPPP
Always have a soft spot for HPPP updates as it was my PhD prelim writing assignment.. The first draft map was just published as a special issue in the journal Proteomics just in time to compile that assignment.. 🤓

[Pastel BioScience @PastelBio]

The Circulating Proteome─Technological Developments, Current Challenges, and Future Trends https://t.co/dlt4YdshLh

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#proteomics #prot-paper

[Simon Duerr @simonduerr]

This is great! @NIAIDNews have launched a collection of public domain illustrations (currently 550 individual icons) https://t.co/qYzIsbr0TH

[Bini Ramachandran @ItsBiniR]

Apparently, a 1000 spectra per second de novo peptide sequencing tool, https://t.co/icyjbSxNdx, enabled those diverse antibody sequence mapping generated from those plethora of protease digestions...

[Pastel BioScience @PastelBio]

News in Proteomics Research blog post \De novo analysis of poly(!!) clonal antibodies from human blood! https://t.co/qBcxr1KiO3

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#proteomics #prot-other

[Mass Spec Pro @massspecpro]

https://t.co/TfDSKdGuqA

[Nature Portfolio @NaturePortfolio]

Hiring managers want applicants to show passion and dedication, but not overconfidence or exaggerations. A feature from @NatureCareers describes how to walk this line. https://t.co/JqidBoJ8fM

[BowTiedBiotech 🧪🔬🧬 @BowTiedBiotech]

Degrader Tac-opedia

🔘PROTAC: E3 ligase-targeted proteolysis
🔘DUBTAC: Deubiquitinase stabilization
🔘LYTAC: Lysosome-targeted degradation
🔘Trivalent PROTAC: Multivalent E3 ligase
🔘AUTAC: Autophagy-targeted degradation
🔘RIBOTAC: RNA-targeted degradation
🔘RNA-PROTAC: RNA-binding E3 ligase
🔘BioPROTAC: Antibody/peptide proteolysis
🔘Aptamer-PROTAC: Aptamer proteolysis
🔘GlueTAC: Lysosomal traffic & degradation
🔘Peptide-PROTAC: Peptide-based E3 ligase
🔘NanoTAC: Nanobody-based E3 ligase

H/T: Donggeon Kim on the HR app!