📌 4 years Pre-doctoral Fellowship in Plant Molecular Biology 🌱🧬 at The Center for Research in Agricultural Genomics, Spain 🇪🇸... Please share and spread the word! For details visit: https://t.co/X4XuWVIoZ6
Today in @Science_Magazine we report the laboratory evolution of compact degrons that enable targeted protein degradation triggered by an otherwise-inert small molecule, a multidisciplinary study that integrates organic chemistry, molecular glues, protein evolution, genome editing, and structural biology.
PDF: https://t.co/cCVLKL0w8Y
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AlphaFold2 and RoseTTAFold are limited to predicting the 3D structure of proteins. A new all-atom method models complete biomolecular assemblies, including proteins, nucleic acids, small molecules, metals, and covalent modifications. #NBThighlight https://t.co/a9relIlKLC
New CRISPR gene therapy shows promising results in curing hereditary angioedema, a potentially life-threatening inflammatory condition. Number of swelling attacks fell by 95% in initial 6 months for trial participants. A medical breakthrough? 🧬🔬 #CRISPR https://t.co/sTA2zLHA4F
Cresomycin—a novel synthetic molecule—demonstrates remarkably robust efficacy against multiple, evolutionary divergent forms of antimicrobial resistance, researchers report in Science. https://t.co/ikcGOtyeqY
CRISPR gene editing has the potential to solve many problems in research, agriculture, and medicine. For the special 50th anniversary issue of @CellCellPress, we discuss its past, present and future directions with @MartinJinek and @OanaPelea.
https://t.co/XehPJjTKec
New Article: "Targeting Magnaporthe oryzae effector MoErs1 and host papain-like protease OsRD21 interaction to combat rice blast" https://t.co/gB2D30vltU
Structural approach: design a small molecule that disrupts the interaction between a fungal effector and its target in rice.
A ribozyme that cuts DNA - programmably!!
It has a ways to go before it can be a precision genome editing tool - short target recognition sequence, doesn’t bind dsDNA well - but an exciting discovery nonetheless!
Study from @GogoLiu lab at @Tsinghua_Uni, published in @ScienceMagazine
The 2024 Workshop Series will start with "Practical Considerations for Plant Genome Editing".
Speakers will provide practical information and best practices for a successful CRISPR experiment. Beginners and experienced users will find useful info.
#CRISPR#AcademicTwitter
Feb Special Issue on 21st century tools in plant science. Read FREE: AI in plant science and publishing; 100 important questions facing plant science derived using LLM; Click chemistry in plant science; Single cell stereo-sequencing technology & more https://t.co/S7yERLSAO0
An RNA viral vector facilitates CRISPR-Cas genome editing in tomato. Fantastic collaboration with Antonio Granell lab (@IBMCP). https://t.co/2LnqIOFYbl
Genetically edited cherry tomatoes now grow like grapes and mature in just 40 days, paving the way for sustainable urban and space farming. Cool Down | Tomatoes ready for harvest in 40 days? https://t.co/mvIiyFNl6c
Capture of regulatory factors via CRISPR–dCas9 for mechanistic analysis of fine-tuned SERRATE expression in Arabidopsis
https://t.co/DntHbSlE92
#plantscience ♻️
Genetically encoded Boolean logic operators to sense and integrate phenylpropanoid metabolite levels in plants
https://t.co/k2t2UoIz3I
#plantscience ♻️