Jacob Allen

Associate Professor at UIUC | HK | Microbial Systems Initiative | Integrative Microbiota Physiology Lab

[Jacob Allen @JacobAllenPhD]

🚨Interested in why fermented foods may be important for health? Check out our new pub describing a class of microbial metabolites that are abundant in fermented foods and are modifiable to enhance food matrix bioactivity towards a key immune receptor-AhR
https://t.co/PjdVkV9aPy

[Jacob Allen @JacobAllenPhD]

What a treat it was to have @Mucus_Man visit @IGBIllinois yesterday! Great to steal him away from his shrimp experiments for a day and hear about his labs exciting new science (Mucus and non-mucus related) Not surprising that some cool new stories are coming out soon!

[College of AHS @AHSIllinois]

A new study by @IlliniHealthKin researchers has identified a pathway by which social stress can worsen symptoms of inflammatory bowel disease—a commonly reported phenomenon for those with IBD.

Read the full story ➡️ https://t.co/u0NONBSVUm

[Jacob Allen @JacobAllenPhD]

@DrHArmstrong
@BrainBehavImm
@IllinoisMSI
@IlliniHealthKin

[Jacob Allen @JacobAllenPhD]

Breaking the X hiatus for a New Paper Alert 🚨
We describe how Social stress increases IBD susceptibility in mice via adrenergic signaling and epithelial ROS.
Huge congrats to the whole team & espec. Elisa Caetano-Silva for leading the charge!
@AHSIllinois https://t.co/dwaEk1ALL3

[Dr. Heather Armstrong @DrHArmstrong]

📜Our paper officially published w/ @JacobAllenPhD and team!👇👇
Social stress worsens colitis through β-adrenergic–driven oxidative stress in intestinal mucosal compartments: β-adrenergic and ROS pathways as therapeutic targets for stress-exacerbated IBD.
https://t.co/BSSde5slAA

[Jacob Allen @JacobAllenPhD]

@SGrivennikov @JustinPerryPhD Just my 2 cents of course:)

[Jacob Allen @JacobAllenPhD]

@SGrivennikov @JustinPerryPhD Correct! I think they go hand in hand. Overload reviewers on grant submissions means less time on each one, less focus on details. Means AI writing quality can cover up what used to be large holes appear as small holes. Also more grants = spread to less qualified reviewers,

[Jacob Allen @JacobAllenPhD]

@SGrivennikov @JustinPerryPhD Grants that look better than the science that backs it up.

[Jacob Allen @JacobAllenPhD]

@JustinPerryPhD @NIH @NIHDirector_Jay Agree. Good outline, but… where are the action items?

[Jacob Allen @JacobAllenPhD]

Fun day with the lab celebrating ⁦@MikaelaK_RD⁩ PhD and arrival of new student Eleanor Eck! See Mikaela’s new lab coat with some fermented food “bling”… I focused on design, but I forgot about the size (an XXL… Mikaela is 5 ft 2… 😬). Correct size is inbound :)

[Jacob Allen @JacobAllenPhD]

@GutBugs2

[Jacob Allen @JacobAllenPhD]

Check out the commentary I wrote on some cool new metagenomic workflows from Elisa Caffrey and the Sonnenburg lab. New ways to study fermented food microbes :). https://t.co/4R0Fh52DhW

[Jacob Allen @JacobAllenPhD]

@TniaMedeiros7 @ScienceMagazine Awesome science and story! Congrats.

[Tânia Medeiros @TniaMedeiros7]

My paper is out in @ScienceMagazine!

We found a novel host defense strategy where #mitochondria, our domesticated microbes, compete with the intracellular pathogen #Toxoplasma for #folate.
https://t.co/cDwlHtS4kB

[Jacob Allen @JacobAllenPhD]

@Mucus_Man Congratulations!! Well deserved.

[Jacob Allen @JacobAllenPhD]

@RondaCarlotta @harriswangnyc @natBME 😎. Awesome 👏

[Carlotta Ronda @RondaCarlotta]

What if we could use precision #microbiome editing in vivo to turn harmful gut microbes into allies against disease? We did it using #CRISPR Transposon & mobilome engineering. With @harriswangnyc and Tyler Perdue. In @natBME
👉 https://t.co/CbMkQH8FF7
👉 https://t.co/fY0pREBBUe

[Christopher Gardner @GardnerPhD]

Just published!

Congrats to lead authors, Dalia Perelman & Elisa Caffrey, on publishing "Unpacking Food Fermentation" in Advances in Nutrition.
They explore what we know (and don’t) about fermented foods & why clearer definitions & research matter.

🔗 https://t.co/s2s4NLJPzq

[Jacob Allen @JacobAllenPhD]

@JustinPerryPhD @NutritionNerd And will kill those without it. In end, will have exact opposite effect as to what @NIHDirector_Jay said was needed. New minds with innovative ideas. This will crush that.

[Jacob Allen @JacobAllenPhD]

@JustinPerryPhD @NutritionNerd Hmm,except for people trying to keep their labs afloat. Or new investigators that were scored really well this year. Let’s say 12th percentile, and then don’t get funded because of this. This isn’t me btw, but people I know. Like all austerity measures, those with capital survive