Sophie Janssens Lab

Laboratory for ER stress and Inflammation, VIB-UGent Center for Inflammation Research.

[Lars Vereecke @LarsVereecke]

Registration is open for Mucins in Health and Disease! 15–18 June 2026, Ghent - Belgium

All info on: https://t.co/Sinxa8VK6x

Travel awards available from @socmucimm and @MucosalImmunol

#Mucins #MucosalImmunology #Microbiome #Inflammation

[Sophie Janssens Lab @JanssensLab]

@LarsVereecke @MaudeJans @magdalenakolata Congratulations, Lars and Han, and all co-authors! Beautiful work!

[Sophie Janssens Lab @JanssensLab]

Thrilled to present our unpublished work on how dendritic cells decode LNP-embedded antigenic cargo at the @ESGCT meeting in Rome (bit overwhelmed by the amount of people though😱). For all DC and LNP lovers, come find me at 15h3O in Parallel session B.

[Sophie Janssens Lab @JanssensLab]

@JBoettcherLab @KU_Leuven Thanks a lot, Jan, for a great talk! It was fun to host you in Leuven!

[Sophie Janssens Lab @JanssensLab]

@ReiseSousaLab @Victor_Bosteels @InflamResCen Thanks, Caetano😊

[Sophie Janssens Lab @JanssensLab]

Very happy that our review in Nat Rev Imm is out! Trying to shed some light on the many knowns and even more unknowns of homeostatic dendritic cell maturation with @Victor_Bosteels @InflamResCen

[Nature Rev Immunol @NatRevImmunol]

Striking a balance: new perspectives on homeostatic dendritic cell maturation https://t.co/nAaIcpLrsJ

[Sophie Janssens Lab @JanssensLab]

@Xiangyue_CA @Victor_Bosteels Thanks!

[Sophie Janssens Lab @JanssensLab]

@mariska_simpson Huge congratulations Mariska, Mike and Wayne. Great work!

[Sophie Janssens Lab @JanssensLab]

@inoagrafioti @ERC_Research 🤔 good to know, unfortunately it is still something you get to hear…luckily, we know better😉!

[Sophie Janssens Lab @JanssensLab]

@KC_DC_01 @EFIS_Immunology @EurJImmunol @society_belgian @ugent @VIBLifeSciences Congrats, Charlie! Well deserved!

[Sophie Janssens Lab @JanssensLab]

@P_Tougaard Great job, Peter and Mario!

[Sophie Janssens Lab @JanssensLab]

Interested in dendritic cell biology and/or IRE1 signaling? Ready for a new challenge in the city of Ghent? If the answer is 2x yes, please check the VIB website for open positions for a PhD student https://t.co/JqPn7yor3H and a postdoc https://t.co/tKebwpPUDm in the @JanssensLab

[Sophie Janssens Lab @JanssensLab]

So now we finally know why IRE1β behaves as it does: it just needs its partner in crime, AGR2, to calm down.

[Sophie Janssens Lab @JanssensLab]

Great job by @ClootsEva and Phaedra from the Janssens lab! Happy to see their work out in @embojournal.

A fun and collaborative effort with @VIBEyckermanS and @SavvidesLab.
@VIBLifeSciences @InflamResCen

Time for a thread!
https://t.co/OLxsawmAnL

[Sophie Janssens Lab @JanssensLab]

AGR2 is a pretty interesting protein, especially upon mutation of H117 to Y: this causes massive inflammatory phenotypes in patients. Turns out that the H117Y mutant is also completely incapable of blocking IRE1β activity!

[Sophie Janssens Lab @JanssensLab]

Very proud PI with a fantastic PhD defense of @Victor_Bosteels @InflamResCen. Thanks at Caetano @ReiseSousaLab and Fabiola @Fbosorioo for coming all the way from London and Chile to join us. All the best to Victor for his new adventures in @bart_lambrecht and @ReiseSousaLab!

[Sophie Janssens Lab @JanssensLab]

@NeckerInem @ugent @vanendert_peter Looking forward to it!

[Sophie Janssens Lab @JanssensLab]

@HiLIFE_helsinki @LifeSciHelsinki @HelsinkiUniMed It was an immense pleasure to see where my old fried and very first PhD student @Leonardo_ASouza has landed meanwhile. Thanks a lot at @HiLIFE_helsinki and especially at Leo for hosting me! Looking forward to some new collaborations!