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Jay Keasling
@jaykeasling
Synthetic biologist who engineers microbes to produce chemicals
Berkeley, California
Joined April 2009
89 Following
4.5K Followers
72 Posts
Excited to share our latest publication in @NatureComms! We developed a PKS-based platform for the controlled biosynthesis of high-energy fuel molecules with tunable cyclopropanation patterns. Congratulations to Dr. Kevin Yin for leading this work!
https://t.co/ueKVkK6t8L
Peter and Graham discovered that GuUGT73F15, an enzyme from licorice plants, catalyzes C3 β-O-glycosylation reactions with a remarkably wide range of triterpenes/sterols and UDP-sugars. This method can be used to synthesize libraries of saponins as candidates for improved drugs.
2/2 The team achieved titers of 1.84 g/L and showed that these #renewablemonomers can be used to create recyclable plastics with tunable thermal and mechanical properties.
Congratulations to the entire team on this incredible achievement!
Read it here: https://t.co/l1xbuxI9DE
We are proud to have trained many generations of scientists, educators, founders, policymakers, and more! Happy Holidays from the Keasling Lab--with a record of attendees! 🎉 May 2026 be full of scientific achievements, education, and social impact. 🧬🌎
🧐: Can you find Jay?
Who to follow
Keasling Lab 🏳️🌈🏳️⚧️
@Keasling_Lab
Twitter account for the lab of UC Berkeley Professor @JayKeasling at @JBEI. Tweets by lab members 🧬
Christopher Voigt
@Geneticdesigner
Composing DNA / Professor and Department Head @ MIT Biological Engineering
Michael C. Jewett
@MichaelCJewett
Professor of Bioengineering, Stanford University
Each year, the Keasling Lab gathers in Lake Tahoe to reflect on our progress, share goals, and think collectively about where our science can have the greatest societal impact. Proud of what we accomplished together—thank you to everyone who makes this work possible!
Happy to share our new paper out in #MetabolicEngineering! We developed a strategy to tie redox activity to the growth rate of E. coli. Growth coupling enables enrichment of high-activity variants from large mutagenesis libraries for protein engineering. https://t.co/j78HKJpXY7
You can find our QS-21 paper here: https://t.co/N3H2crjXY4
Last week we published a landmark paper in Nature describing the production of the world's leading vaccine adjuvant, QS-21, in yeast. This work will pave the way for affordable, readily available, effective vaccine adjuvants for the world.
Our latest research has just been published today in the journal Nature. We engineered yeast to produce the cancer therapeutic vinblastine. You can find the work here: https://t.co/kJdVcPDEM1. It is the longest biosynthetic pathway ever refactored into yeast.
I am proud to announce that Zero Acre Farms, a company I co-founded, has released its first product, cultured oil. It’s low in bad (poly-unsaturated) and high in good (mono-unsaturated) fats. You can find it @ZeroAcreFarms.
Check out our recent article in Joule about production of high energy fuels.
Biosynthesis of polycyclopropanated high energy biofuels https://t.co/l7Eqh9tPmJ
@ZeroAcreFarms I am very excited to announce Zero Acre Farms! We are bringing an end to destructive vegetable oils.
Last weekend’s visit to Miami for Art Basel was amazing! @ Art Basel Miami Beach https://t.co/HzV9CICHpC
Check out the summary here!
https://t.co/InBmH2NQKp
https://t.co/BLvsujHkQL
New paper describing our work to engineer yeast to produce cannabinoids https://t.co/uCpyTrjbIz
From @jbei @jaykeasling @NathanHillson @BerkeleyLab @LBNLBioSci in @NatureBiotech: a new way to synthesize DNA sequences through a creative use of enzymes that promises to be faster, cheaper, and more accurate: https://t.co/wdsV37cvwj #synbio
Researchers @jbei @berkeleylab announced they have pioneered a new way to synthesize #DNA sequences through a creative use of enzymes that promises to be faster, cheaper, and more accurate. #bioengineering @jaykeasling https://t.co/gQpkCXZru1
De novo DNA synthesis using polymerase-nucleotide conjugates https://t.co/gvo0bcnDbi
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