Journal of Cell Biology

The Journal of Cell Biology (JCB) publishes peer-reviewed research on all aspects of cellular structure and function. Est. 1955 - @RockUPress

[Journal of Cell Biology @JCellBiol]

An excitable #Rho #GTPase signaling network generates dynamic subcellular contraction patterns, by Melanie Graessl, Johannes Koch, Leif Dehmelt, Perihan Nalbant et al. https://t.co/RRaybeOIcm

📕 In “Collective Behaviors and Self-Organization in Cells”: https://t.co/J4R0IzebjR

[Journal of Cell Biology @JCellBiol]

Gierke, Gadomska, Brandstätter et al. @UniFAU show that the synaptic ribbon-associated protein Piccolino is essential for synaptic vesicle tethering at sensory synapses, and propose a direct protein–lipid interaction as the underlying molecular mechanism. https://t.co/QaJTpOTZIt

[Journal of Cell Biology @JCellBiol]

Excitable RhoA dynamics drive pulsed contractions in the early #Celegans embryo. From Jonathan B. Michaux, François B. Robin, William M. McFadden, & Edwin M. Munro: https://t.co/36SYlUJePn

📕 Part of “Collective Behaviors and Self-Organization in Cells”: https://t.co/Hb8sZsGQVl

[Journal of Cell Biology @JCellBiol]

@TulaneMedicine See a recent JCB study from Youfang Zhou and Xianfeng Wang et al. of the Wu-Min Deng lab, "Polyploidy reprograms epithelial cells for motility and phagocytosis via stress signaling"
👉 https://t.co/natmi0r9vg

📰 Press release: https://t.co/xQPoJse7Yl

[Journal of Cell Biology @JCellBiol]

“We felt that JCB was an ideal venue to reach a broad audience interested in both fundamental cell biology and disease mechanisms.” — Wu-Min Deng (@tulanemedicine). JCB is where the world meets your research. Learn more 👉 https://t.co/CtOmRDdkk2

[Journal of Cell Biology @JCellBiol]

Mori, Ohtsuka et al. @yamanashi_univ demonstrate that the presynaptic active zone proteins CAST and ELKS directly interact with endophilin-A to maintain the functional synaptic vesicle pool, redefining their roles beyond structural organization. https://t.co/XygST44k2n

[Journal of Cell Biology @JCellBiol]

Mariyah Saiduddin, @remlehmann et al. @WhiteheadInst @MITbiology show that membrane lipid composition establishes the soma-germline boundary in the fly embryo. https://t.co/5hEXSRKQHi

#Drosophila #CellSignaling #StemCells

[Journal of Cell Biology @JCellBiol]

Victoria E. Deneke and Stefano Di Talia review how the spatiotemporal coordination of cellular functions across large distances is controlled by chemical waves. https://t.co/DJY55bAQAt 📕

📕 Part of “Collective Behaviors and Self-Organization in Cells”: https://t.co/OBeGztA2qr

[Journal of Cell Biology @JCellBiol]

#Myosin 1b promotes axon formation by regulating #actin wave propagation and growth cone dynamics. From Olga Iuliano, Evelyne Coudrier, and colleagues: https://t.co/W3LfS3ukVd

📕 Part of “Collective Behaviors and Self-Organization in Cells”: https://t.co/a3nSWXzdMU

[Tomohito Higashi @To_Higashi]

私たちの論文がJ Cell Biol誌に掲載されました。上皮細胞の「角」がリモデリングを受ける際に、PAK4というキナーゼが接着強度を保ちバリア機能を維持するために重要な役割を果たすことをミシガン大学のAnn Miller研と共同研究で明らかにしました。筆頭著者のBabliさんはじめ共著者の皆様に感謝します。

[Journal of Cell Biology @JCellBiol]

Adhikary, @To_Higashi et al. show that PAK4 drives dynamic vertex remodeling in cells and embryos through spatiotemporal regulation of #myosin II. Inhibition of PAK4 disrupts tissue packing and compromises junctional continuity and barrier function. https://t.co/F3fLdSmXkc

[Journal of Cell Biology @JCellBiol]

Ani Michaud, @GoryachevAndrew, von Dassow, @BementLab et al. identify a versatile cortical pattern-forming circuit based on #Rho, F-#actin, Ect2, and RGA-3/4: https://t.co/Etaz43VlAM

📕 Part of “Collective Behaviors and Self-Organization in Cells”: https://t.co/rGIVL2bL0c

[Journal of Cell Biology @JCellBiol]

Colarusso, Wirshing and Lew @mit find that the multibudding yeast Aureobasidium pullulans can position cytokinetic machinery at most bud necks even in the absence of #septins, revealing a novel pathway to mark #cytokinesis sites. https://t.co/2xVvZdZygc

#CellDivision

[Journal of Cell Biology @JCellBiol]

Spotlight: New study by Begar et al. from @CytoLabKoc (https://t.co/HKD2oASutQ) reveals how PCM1 multimerization drives assembly of centriolar satellites and recruitment of client proteins. Kearney, Sharma, and Morrison highlight the findings: https://t.co/ln19Z1kFq8
#Cilia

[Journal of Cell Biology @JCellBiol]

Growth-dependent concentration gradient of the oscillating Min system in Escherichia coli. From Claudia Morais Parada, Ching-Cher Sanders Yan et al. https://t.co/YaZNDg4QRk

📕 Part of “Collective Behaviors and Self-Organization in Cells”: https://t.co/wPP7BWyaMk

[Journal of Cell Biology @JCellBiol]

Unattached #kinetochores cluster in budding #yeast to promote #microtubule capture. Mallett, @SueBiggins et al. dissect the molecular mechanisms of this pathway, showing Mps1 kinase regulates an interaction between Stu1 and Slk19 to drive clustering. https://t.co/x35Ug4nfuq

[Journal of Cell Biology @JCellBiol]

Arp2/3-dependent #endocytosis ensures #Cdc42 oscillations by removing Pak1-mediated negative feedback. From Marcus Harrell, Ziyi Liu, Maitreyi Das and colleagues: https://t.co/5ahvt7he86

📕 Part of “Collective Behaviors and Self-Organization in Cells”: https://t.co/opU1VabATh

[Journal of Cell Biology @JCellBiol]

This collection was curated by JCB Editorial Board member Min Wu and Scientific Editor Gabriele Stephan. Blending aspects of mechanobiology, developmental biology, and signaling, we hope this collection will engage a broad readership interested in biophysics and systems biology!

[Journal of Cell Biology @JCellBiol]

This collection explores emergent phenomena incl. how cellular events are rapidly coordinated by waves of chemical & electrical signals, how tissue patterning is governed at the cellular level & how cellular interfaces guide cellular migration & morphology https://t.co/ZdhNu2nAG0

[Journal of Cell Biology @JCellBiol]

New study led by Lei Wang from the Institute of Biophysics of @CAS__Science (https://t.co/qeo662CiWJ) has revealed two coordinated molecular mechanisms that maintain efficient protein phosphorylation in the Golgi apparatus during lactation. 👉 https://t.co/QW8Ba9Ea82