JChen Lab

Phages, bacteria, and pathogenicity islands. @NUSMedicine.

[JChen Lab @JchenLab]

Our latest! Phages no longer own transduction! Staph pathogenicity islands engage in lateral transduction and can also piggyback LT to drive genome hypermobility. Amazing work by @melchee92 @DrEsterSerrano @rbacigalupe @jrpenades @jrossfitz and others! https://t.co/Y9g2PyaTed

[Tania Wong @TaniaWong88]

Pleased to share our latest study @NatureComms. We show that the host metabolites fumarate and itaconate impose selective pressure on Staphylococcus aureus, driving its adaptation via the enzyme FumC. Grateful to all who contributed to this work!
https://t.co/D2MoAWEdQd

[Fernando de la Cruz @FdlC61]

A new encyclopedic review, for plasmid lovers:
https://t.co/2ANVSvbeAX
We (Mapi, Eduardo and I) hope you like it!

[Victor J. Torres @TorresVJ_Lab]

1/11 New #MRSA #Staph publication from Dr. Diane Boff a talented former postdoc co-mentored by the @TorresVJ_Lab and @DrShrutiNaik!

https://t.co/sjFz7v8Ffa

[JChen Lab @JchenLab]

@Yuanqiao1002 Congrats!

[Anat Herskovits Lab @AnatHerskovits]

Happy to share our new preprint describing prophage encoded anti-phage defense system,TERi, that targets the terminase complex of invading phages to inhibit DNA packaging. The system also encode self immunity proteins that protect the prophage.

https://t.co/q8kq7sBquR

[José R Penadés @jrpenades]

New mechanism of gene transfer! With @CostaT_Lab @CBRB_Imperial, cf-PICIs form tail-less elements that, once released, spread among different bacterial species by hijacking tails from various phages. More exciting news soon! https://t.co/AItq6UQAAc

[Yuan @Yuanqiao1002]

We have a fully funded PhD scholarship for Aug 2025 intake.

If you are interested in joining our research group, please check the admission requirement on the website and contact us.

https://t.co/d7Md3hqB9D

[Andrew millard @milja001]

PhD projects at University of Leicester
Including three phage projects ....
With @MarthaClokie , and me. Including an iCASE project with Dr Abhinav Koyamangalath Vadakkepat , using cryoEM

https://t.co/Lu9PwDgx36

[George O'Toole (he/him/his) @GeiselBiofilm]

Pls share: Microbiology faculty position available at Texas A&M University.

[Anat Herskovits Lab @AnatHerskovits]

Our paper is finally out at Nature Microbiology. A team effort discovering Tailocin cell factories. Listeria monocytogenes bacteria produce and store ~6000 tailocins per cell in a remarkable way.

https://t.co/VrnD13KOgk

[JChen Lab @JchenLab]

@hauryliuk @Eppendorf_Group We had a similar problem. For us it was was Qiagen minipreps. Some people don’t angle the lids of the tubes correctly in the elution step. The lids break off and they cause damage before being pulverized to dust.

[JChen Lab @JchenLab]

@jrpenades Congrats! Nice work Jose, @Lingchen_H, and team!

[Victor J. Torres @TorresVJ_Lab]

1/7 Happy to share a new publication from the team spearheaded by @Keenan__Lacey published today in @ScienceAdvances. This project was started at @nyugrossman and was completed @StJudeResearch by @APickrum and A. Castellaw. https://t.co/NEnsgWE305

[JChen Lab @JchenLab]

@yunnhwen @KJwushuguy @TrevorLithgow Congrats to all!

[Filloux lab @FillouxLab]

Our T6SS paper on TssA is now available @NatureComms
A publication marathon but so happy to see this accepted on my birthday
TssA is an intriguing protein providing specificity and fine tuning in T6SS assembly and firing.
Thank you so much for your brilliant work Selina et al

[JChen Lab @JchenLab]

@jrpenades Congrats, Jose! For sure you earned it!

[Antonia Sagona @antonia_sagona]

Thank you to our excellent reviewers and Editor for helping us to improve significantly this review with their very useful comments!

[JChen Lab @JchenLab]

@jrossfitz @roslininstitute @EdinburghUni @RoyalSocEd Congrats, Ross!

[Jakob T Rostøl @jakob_tr]

Just missing April fool's, here is something that is no laughing matter:
https://t.co/HCNdsSbcY3
In @NatureMicrobiol, we describe how a prophage avoids autoimmunity from its own defence systems