Jeremy Raymond

Postdoc at @UniofOxford. Exploring how the melanocytic lineage can go wrong. Development | Pigmentation | Melanoma.

[Pietro Berico @locusbearico]

New preprint from the Hernando lab!
https://t.co/yVCWP8ZfVE

Combining 3D genome profiling and high resolution imaging we demonstrate how chromatin architecture cooperate with mechanical confinement in conferring melanoma mesenchymal cells high migratory capacities.

[Journal of Cell Biology @JCellBiol]

Richards, Devenport et al. @princetonmolbio show that #melanocyte precursors form dynamic E-cadherin based attachments to surrounding #keratinocytes that stabilize migratory protrusions and sustain long-distance #migration as they colonize the #epidermis. https://t.co/iqMRPGxmwL

[Nature Reviews Cancer @NatureRevCancer]

#JournalClub 🚨

Basurto-Lozada & Robles-Espinoza @UNAM_MX discuss a study that challenges the prevailing view of a monoclonal origin of cancer by showing that early lesions in mouse models of colorectal cancer are polyclonal.
📖⬇️
https://t.co/DIUyxbfBXt

[Satish Bodakuntla @S_Bodakuntla]

Thrilled to share with you all that our paper is now online in Nature. Many thanks to all the collaborators and mentors throughout the journey 😀
https://t.co/lQRnylXlvV

[Vicky Tan @vicky__tan]

We excited for Ben Hogan's (Peter Mac, Uni of Melbourne) talk at #ZDM18! Ben will sharing his lab's work on using sc-genomic approaches to explore lymphatic development, regeneration and the blood brain barrier. Don't miss his talk on Oct. 13th at 14:30 in Boston or online!

[eLife - the journal @eLife]

🧬 August’s most-read #genetics paper shows how a new zebrafish tool (mitfa:Cas9) can reveal the genes driving melanocyte and melanoma development: https://t.co/xtMclwwaUf #CRISPR

Have a paper people should see? See what our Editors look for: https://t.co/ZJpcIXNkah

[eLife - the journal @eLife]

How do genes that keep melanocytes alive affect #melanoma?

Using a #zebrafish line with mitfa-driven Cas9, researchers show that knocking out survival genes can sometimes fuel more aggressive tumour traits.
https://t.co/r84CzqrVL3

[richard white @whitefishlab]

Now out in @elife, @SarahPerlee’s Ph.D. work developing a powerful way to knock genes out in #melanocytes and #melanoma cells. She created #zebrafish that allow for efficient CRISPR editing, and found unexpected things about genes required for these cells to thrive: https://t.co/Y1duw8cgRV

[richard white @whitefishlab]

Cancer cells are notoriously plastic, but what triggers the changes in cell state? In our new @nature paper, Miranda Hunter found that mechanical pressure is a key to this switch. Check it out here: https://t.co/jTlmZ70kaH

[Giorgio Seano @GiorgioSeano]

🧠 Why does glioblastoma always outsmart treatment? In our paper, we identified proneural–mesenchymal hybrid glioblastoma cells that are resistant to therapy and dependent on nuclear import.
https://t.co/kBiblbpsVA
Short walkthrough below. Let’s dive in! 🧵 (1/9)

[nature @Nature]

Nature research paper: Targeting GRPR for sex hormone-dependent cancer after loss of E-cadherin

https://t.co/PryIKjxjNZ