📌 Neoadjuvant Immune Checkpoint Inhibitors Plus Chemotherapy in Early #BreastCancer
A Systematic Review and Meta-Analysis.
https://t.co/ZmtbKUI58g
👉🏻 In this meta-analysis involving 5114 patients
neoadjuvant ICI therapy was associated with improved efficacy outcomes in early-stage TNBC and PD-L1+ HR+/ERBB2- tumors with an acceptable safety profile.
However, in triple-negative breast cancer, no benefit was observed with adjuvant ICI in patients with pCR or residual disease.
Given the financial and toxicity costs associated with ICIs, future research should prioritize identifying patients most likely to benefit from the addition of ICIs to neoadjuvant chemotherapy.
@OncoAlert #OncoAlertAF @JAMAOnc
This prospective-retrospective translational study of patients enrolled in SOFT was the first study in which a genomic assay was able to predict which premenopausal patients were most likely to benefit from ovarian function suppression. https://t.co/TKEshvcpPU
Sentinel lymph node biopsy may have similar outcomes as axillary lymph node dissection when most of the patients go on to receive radiation therapy, finds pooled analysis. https://t.co/YnRXV8zPWF
In honor of (belated) #ClinicalTrialsDay, consider referring your #breastcancer#patients in the S. Florida area w/ #GSM +/- painful sex to our #PRP trial! Patients can be any HR status, on or off endocrine. We have enrolled 7/20 patients 🔬so far! https://t.co/GA74IZ0JCy
Shout out to our amazing past breast fellow @AnshumiDesai and current postdoctoral fellow going into PRS on her presentation of the “10 Commandments for A Grisotti Flap” @ASBrS
Amazing overview by my mentor @kristinrojasmd on fertility disparities existing in the breast cancer patient population. As @SocSurgOnc@ASRM_org@acog and @NCCN highlight, fertility options should be discussed as early as possible, before treatment starts. ART is SAFE and FAST!
🛑✋You will want to make some time in your busy schedule for this one today! Join SSO Women in Cancer Surgery today at 7pm Central to learn How to Get More Done and maximize your day.
Hold Your Spot Now: https://t.co/7sZXIS0QSW
Dr. Jennifer Ligibel presents the first data from the BWEL trial- a lifestyle based intervention results in significant weight-loss in breast cancer survivors! Still waiting to find out if impacts on recurrence @DanaFarber@ALLIANCE_org