New from our group in @JAMADerm: Skin eruptions after lifileucel/IL-2 for advanced melanoma are common (50%), self-limited, and prognostically favorable - ~7x higher odds of radiographic response at day 42.
@JordanTSaid@gmboland@bbuchbinderMD@dliu_ccb
https://t.co/RkakHv8EjV
🤗 Thrilled to see this out in JAMA Derm - was fantastic to be part of this collaboration with the DFCI and MGB oncoderm and melanoma TIL teams! New therapies, new rashes! ♋️ 💉
In advanced #Melanoma, lifileucel-associated purpuric morbilliform eruptions were linked to higher 42-day radiographic response rates, suggesting prognostic value as a short-term efficacy marker. https://t.co/YPW0Ko1Knf
The time of day for cancer immunotherapy is associated with major outcomes. Early is better. Results from a randomized trial of lung cancer, backs up the importance of our circadian rhythm and immune system
https://t.co/bHqUZ3U83O
This is a major story from #ASCO25. Randomized phase 3 trial of time of day of immunotherapy infusion. Randomized to infusion before or after 3pm. Early infusion far superior: PFS 11.3 vs 5.7 HR 0.42, OS HR 0.45! Impactful, pragmatic, not costly. This should be a bigger story.
We show that #CHIP is a novel risk factor for ICI myocarditis 🫀, similar to risk of dual ICI therapy. This has implications for evaluation of CHIP in those planned for ICI therapy & tailoring monitoring strategies. https://t.co/RtlZqToSPe #CHIP#Immunotherapy@Yale
Happy to share our recent pub: Development and Validation of Algorithms to Identify Individuals With Cutaneous Lupus From Healthcare Databases; hopefully facilitates administrative claims database work in CLE @UTSWDerm https://t.co/CvQ82eUPiu
1 year after #BarbieMovie’s release, we asked whether the movie’s closing joke spurred public interest in gynecology in a study out today in @JAMANetworkOpen (led by Eva Sénéchal, w/ @Bray_Charles_ & @AnupamBJena)
🧵👇
🔓paper: https://t.co/lTl53Rlunp
@wbpictures @RPLuckyChap
Please join us in congratulating all of our 2024 Boston Marathon runners!! Amazing job everyone!!
🏃♀️🏃♂️🥇💪
Dr. Nicole LeBoeuf
Dr. Hillary Tsibris
Dr. Nicole Gunasekera
Jeremy Odena, LPN
& thank you to all of our BWH Dermatology Boston Marathon volunteers and supporters!!
It’s that great time of year when we find out about the next generation of MDs joining us at @BrighamWomens!
Welcome to the incredible new @BrighamMedRes Intern Class of 2024!
Amazing to see that 21% from URIM backgrounds! @Brigham_DI
Purple bumps, inpatient Derm, and Oncoderm galore! 💜
No better way to start off a week than with a great @BrighamMedRes Med-Derm morning report, especially with @AMostaghimi! (will have to remember my bow tie for next time…)
Phenomenal @BrighamMedRes morning report with the med derm dream team @JordanTSaid and @AMostaghimi exploring the “purple bump” differential in oncology patients! 🟣
This morning, I spoke at my alma mater to @BrighamWomens residents and faculty to talk all things medicine and public health. I wouldn’t be where I am today without the extraordinary mentors and colleagues at BWH—will always be grateful for them.