Judith Simcox PhD

Associate Professor @UWBiochem studying lipid signaling and regulation | HHMI FHS | opinions are my own and do not reflect those of my employer

[Judith Simcox PhD @JudithSimcox]

Thrilled to have our story on the regulation of lysosomal lipids out in @Cell_Metabolism! The work was led by two outstanding grad students @_JessDavidson and Raghav Jain probing mechanistic control of energy expenditure @HHMINEWS @UWBiochem

[Cell Metabolism @Cell_Metabolism]

New! Online now: Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV https://t.co/QcT4tpbNWl

[Guo-Cheng Yuan @gc_yuan]

We are recruiting a postdoc to build ML/AI tools to integrate spatial multiomics to study cancer and neurodegenerative diseases. https://t.co/V3Uu2A6wXe

[UW–Madison Biochem @UWBiochem]

Deadline Oct. 15: We are hiring for a professor at any level to join our creative and dynamic community. Candidates in all areas of #biochemistry will be considered, and we are particularly interested in candidates in systems and synthetic biology. https://t.co/FPjWCU0bBf

[Judith Simcox PhD @JudithSimcox]

Please spread the word on hiring in our department. We are searching broadly but particularly interested in Systems and Synthetic Biology. I am chairing this faculty search, please feel free to reach out if you have any questions.

[UW–Madison Biochem @UWBiochem]

Deadline Oct. 15: We are hiring for a professor at any level to join our creative and dynamic community. Candidates in all areas of #biochemistry will be considered, and we are particularly interested in candidates in systems and synthetic biology. https://t.co/FPjWCU0bBf

[Dr. Chrystal Ama Starbird PDB Depositer @drstarbird]

And…

I am SO excited to share our first research preprint! In this paper we determined several cryoEM structures to visualize the entire cell-to-cell bridging complex formed by TAM receptor and ligand, bringing into 3D a common graphical depiction.

https://t.co/nP2VmaC3Jz

[ShorterLab @ShorterLab]

A phosphoproteome atlas of human cell lines reveals the landscape of kinase activity: https://t.co/hidlJ963x5

[Long Lab @longlabstanford]

Lac-Phe is an exercise💪 and metformin💊 inducible blood-borne metabolite that suppresses appetite. How does Lac-Phe get into circulation? New from @Shuke_Xiao: a transporter deorphanization story that links local cellular metabolism to systemic activity:
https://t.co/19eVP5nKXx

[Pagliarini Lab @Pagliarini_Lab]

Is phosphorylation broadly relevant to mitochondrial protein function? In work led by @AJsmith231, we silenced 10 mito phosphatases, mapped dynamic sites, and revealed functional implications for import, catalysis, and morphology.
https://t.co/eeu6BzKL7z
# Mitochondria
#HHMINews

[Katalin Susztak @KSusztak]

Our 🆕 paper alert ‼️ Cardiovascular-kidney-metabolic syndrome as a mitochondrial systems disorder our review published in @NatRevNeph @AranyLab @IntMedAbel @pei_liming @JosephABaur https://t.co/5bgWV598h5

[Leslie Vosshall PhD @leslievosshall]

Awesome paper on bitter taste in the #mosquito
Congrats @BenMatthewsUBC @trevor_sorrells and co-authors!
https://t.co/eLVtpEfkfu

[Lingjun Li Research Group @LiResearch]

Our latest study is out in Nature Protocols 🥳
We present tissue expansion mass spectrometry imaging (TEMI) for high-resolution multiomics mapping of lipids, metabolites, N-glycans, peptides, and proteins 👏
Congrats to all co-authors! 🎉
https://t.co/9pczJiTQag

[Judith Simcox PhD @JudithSimcox]

Rest easy Bob https://t.co/bacZNOw6p3

[Judith Simcox PhD @JudithSimcox]

I was so lucky to be trained by the late Bob Cooksey as a grad student the McClain lab. Bob was the senior scientist who taught me to respect the HPLC, mentored me through troubleshooting, and led by example. Such an impressive legacy of more than 200 scientific publications.

[Cell Biology J-Club @cell_club]

Version of record. Lipids regulate export of lysosomal enzymes from the endoplasmic reticulum | PNAS https://t.co/I67lTsXSXn

[Vamsi Mootha @VamsiMootha]

Our MGH Dept of Molecular Biology is hiring. It’s an exceptional *basic* science dept with a longstanding track record for curiosity driven science, great colleagues / infrastructure and generous support.

Assistant Professor https://t.co/nuJKyrvLUn

[Vamsi Mootha @VamsiMootha]

Our preprint is now published: In collab. w/ Ruma Banerjee we show how the B12 chaperone MMADHC spends its life in two cellular 'zip codes' dictated by the mitochondrial PMF (similar to PINK1). Co-led by @Sneha_Rath_, Zhu Li. https://t.co/5gv3sjinA4

[Nate Krah @N8Krah]

🧵 the Krah Lab opens this month and our first preprint is live on bioRxiv!

This was a highly collaborative project with the Chaix Lab, @Dorrance_Lab and @RutterLab asking: does the modality of weight loss change how blood and inflammatory cells are made?

https://t.co/rW3MPbn6XA

[Isha Jain @ishahjain]

🚨New preprint led by the fearless @AyushDMidha. We find evidence for mammalian branched chain amino acid (BCAA) fermentation in hypoxia and beyond.

Preprint: https://t.co/2Psd1I4yIm

Also check out our tissue hypoxia metabolomics dataset: https://t.co/twNLZQVwWT!!

[Brunet Lab @BrunetLab]

Excited to share our paper on identification of secreted proteins during aging! Using proximity labeling and mass spectrometry, we identify secreted proteins that change during aging in C. elegans! Congrats to Jason Miklas and all collaborators! @JayJWM50
https://t.co/PBorjOlFWe

[Judith Simcox PhD @JudithSimcox]

My department is hiring, join us! Madison is a great place to start a lab. Feel free to ask any questions.

[UW–Madison Biochem @UWBiochem]

We're hiring! The Biochemistry Dept is looking for a professor at any level to join our creative community. Candidates in all biochemistry areas will be considered. Apply by Oct. 15: https://t.co/FPjWCTZDLH

[Dan Michele @MicheleLabUM]

Our department @UMPhysiology at @umichmedicine is hiring a tenure-track assistant professor open to all areas of biomedical research. Come join a supportive department focused on ground-breaking research and training the next generation of scientists!
https://t.co/hNhTj0MEuI