The first scientist to ever reverse human aging just dropped the craziest interview on the internet.
Here are 8 facts David Sinclair revealed about aging that will leave you speechless (THREAD):
1. Cancer & Alzheimer's are symptoms of the same disease.
David Sinclair said: "You can reverse aging by 75% in 6 weeks… by reinstalling the "software" of the body so that it's young again."
This idea sprouted when he proved in his first experiment that you can accelerate aging in mice:
"We took two mice born on the same day—same age, same genetics. We 'scratched the CD' of one mouse, corrupting its software and accelerating its aging. The result was dramatic. One looked far older than its brother."
He believed if you can give aging, you can also take it away.
Tomorrow, I'll share his experiment on how he reversed aging in mice (and then Monkeys).
— @davidasinclair
I just sequenced a human genome to 30× coverage entirely at home.
As far as I know, this is the first time this has been done.
I didn’t step foot in a lab once. Every step - from saliva collection, to running the sequencer - took place in a single room with a dining table + kitchenette.
Six weeks ago, I had never done wet lab biology before.
I used an Oxford Nanopore P2 Solo - the only commercially available sequencing device portable enough to do 30x human genome sequencing at home.
Biggest takeaway - I could build something that combined software, hardware, and molecular biology far faster than I thought was possible.
I can name >100 specific instances where AI helped me solve a technical problem that would previously have blocked me because I lacked access to a domain expert.
For example: how do I save my sequencing run when my DNA extraction yield is 4x lower than I need it to be, and I have this limited set of reagents to hand?
To make this work, I had to navigate multiple disciplines:
- writing software to monitor sequencing runs and orchestrate remote GPU infra for basecalling
- learning + executing 5 hour long molecular biology protocols
- building a hardware device to quantify DNA concentration
Apologies for the hyperbole, but I feel super lucky to be living in 2026.
A few weeks ago I decided to sequence a human genome to 30x at home.
Then I actually did it. And I did it really quickly.
I’ve always believed the No.1 application of AI should be to improve human health.
That work started with AlphaFold, and now at @IsomorphicLabs with the mission to reimagine drug discovery and one day solve all disease!
We are turbocharging that goal with $2.1B in new funding.
La lucha no es de las pacientes, no son luchadoras ni es una batalla, es un camino en el que acompañar.
La lucha es de las instituciones.
Solo sin recortes en la pública, con inversión en investigación, detección temprana (importantísima) se podrá luchar.
#DíaContraElCáncerDeMama
🙃 Ser diferente no solo no tiene nada malo… ¡es lo más divertido!
Aunque parezca una paradoja, la diferencia nos une. Cada mirada particular nos hace más humanos, más completos como grupo.
Gracias por tu valentía, Noa. Que nunca nadie te haga sentir mal por ser única.
📍@UPV
🔴🔴 ATENCIÓN
Acabamos de crear esta página https://t.co/huj6jN7cjO para que la gente pueda indicar en el mapa dónde está y qué es lo que necesita que le lleven.
POR FAVOR, ruego difusión para canalizar la ayuda. Somos muchos voluntarios y poca coordinación.
#Dana#Valencia
🔴El litoral i interior nord de la provincia de Castelló està en alerta per pluges nivell roig. Molta precaució‼️
➡️No agafes el cotxe, no te poses en perill
➡️No t'acostes a zones costaneres i no travesses llits de rius, ni barrancs
En cas d'emergència, telefona a l'1·1·2.
Si estas a la carretera segueix els #Consells112CV👇
HE CREADO UN MAPA CON LINK ABIERTO PARA QUE TODO EL MUNDO PUEDA EDITAR, AÑADIENDO PUNTOS Y DESCRIPCIÓN DE LAS PERSONAS ATRAPADAS: https://t.co/seMOkpssMd ENTRAD, AÑADID DATOS Y ELIMINAD CUANDO SE RESUELVAN #Valencia#INUNDACION#AEMET#TURIA#ALFAFAR#SOSVALENCIA ÁNIMO, FUERZA.
Cómo le explicas a todas las familias afectadas que suprimiste la Unidad Valenciana de Emergencias hace un año, porque era un gasto innecesario, y en cambio has invertido 17 millones de euros en festejos taurinos.
Imagine a future where no one dies from #cancer.
With @CUH_NHS we’re building @CambCancer, a new hospital where scientists and doctors will work alongside patients to transform how we diagnose and treat cancer.
Cambridge is #ChangingTheStoryOfCancer 👉 https://t.co/Q4ex7IUU9l