jun

[alexmag @AlexmagCryo]

Today is the second anniversary of DCI-Lausanne, and we're thrilled to share the incredible news: Our amazing team (especially Sergey and Inay), has just gifted us with the extraordinary achievement of a 1.12A ApoF structure from the Titan without an energy filter! 🚀
@DCI_EM

[Andreas Boland @BolandLab_GE]

🚨Paper alert🚨
Our new work on APC/C regulation revealed by high resolution cryo-EM structures together with the groups of Leifu Chang and David Barford.
Congratulations to Anna Höfler, Jun Yu and all other authors.
The manuscript can be found here:
https://t.co/k5HGqDyfY5

[Adrian Koh @AdrianKoh8]

Results from new detector for @thermofishersci Tundra #CryoEM .
Do I see some donuts?
Join us on 7/13 at https://t.co/v4c3QfNbjw to hear more about how we did it.

Movie credit @lingboyu

[cohesin_papers @cohesin_papers]

The molecular mechanisms of human separase regulation https://t.co/rQtyllMlVh

[Andreas Boland @BolandLab_GE]

Below is a link to Jun Yu's @JunYu_unige review on human separase regulation.
https://t.co/9tDgUPV95q
We summarise recent structural and functional data on separase inhibition, and discuss new ideas how phosphorylation of separase and its substrates may control protease activity.

[Andreas Boland @BolandLab_GE]

The Boland @BolandLab_GE & Loewith @LoewithLab labs are hiring a joint postdoctoral researcher to work in the field of cell metabolism and physiology.
We are looking for someone with strong expertise in cryoET and single particle analysis. @DCI_EM
Please spread the word! 🙏

[cryoEM Papers @cryoEM_Papers]

Visualizing ligand bias at the Mu-opioid receptor https://t.co/3iKy4iC9II

[Lucas Tafur @structureltp]

Happy to share that our paper is finally out! @LoewithLab @3Dstructure

We report the cryo-EM structure of the yeast SEA complex, revealing the interaction between SEACAT (GATOR2) and SEACIT (GATOR1).

Video by @cienciagrafica

1/

https://t.co/RRHJaIwrg4

[Andreas Boland @BolandLab_GE]

Thanks for being given the opportunity to present the work from our lab! It is really so much fun here in Konstanz #EMBOcellcycle2022

And thanks for the picture Lina!

[Prof. Hao Wu @WuLabHarvard]

So excited to have our structure on the B-cell receptor published in Nature online! - thanks to absolutely talented Ying Dong @ying70337209 and Xiong Pi @Sampich4 https://t.co/ArFdeX4pR7

[nature @Nature]

Nature research paper: Visualizing translation dynamics at atomic detail inside a bacterial cell https://t.co/x2FQbE2GeP

[eBIC Beamline @eBIC_Diamond]

This newly published review by eBIC staff discusses recent examples on how cryoET can be used to study membrane remodelling processes. Find the paper here:
https://t.co/Q89F07NI2R

[Ailong Ke's Lab at Yale MB&B @AilongK]

Caspases control programmed cell death in eukaryotes. Type III-E CRISPR harbors caspase-like proteases. Our new Science paper explains how Craspase switches on protease activity in RNA-guided fashion - safe alternatives to Cas nucleases in therapeutics.
https://t.co/6LZKtFes7L

[Andreas Boland @BolandLab_GE]

Looking forward to this seminar. Thanks for the invitation Kai! @zhang_lab @YaleMBB

MB&B Informal Seminar: Andreas Boland, Ph.D.

Structural basis of human separase regulation by securin and CDK1-cyclin B1

https://t.co/lsmUKzZOWU

[CCP-EM @ccp_em]

Talks for the CCP-EM Spring Symposium 2022 are now available to view, by session at https://t.co/AZevwN0d9p

[Peter Shen @shen_utah]

In collaboration with @janetiwasa and Julia Brasch (@zauberhoernchen), we are thrilled to announce that the first chapter of CryoET 101 is officially released! Curious about cryo-ET and if it's the right method for your project? Check it out at https://t.co/Q4PvZGDcBJ.

[Andreas Boland @BolandLab_GE]

Our lab has an opening for a postdoc investigating molecular mechanisms of cell cycle regulation using #CryoEM & #CryoET
As part of the DCI, we have access to several high-end microscopes.
If you’re interested in joining us in lovely Geneva please email to [email protected]

[Andreas Boland @BolandLab_GE]

More information can be found here:

https://t.co/NmrH2aCLb7 ;
https://t.co/dsTJOEvfHv ;
https://t.co/lwJeOAJxBD ;

[Jack Zhang Lab @zhang_lab]

We are pleased to share our structure with the community. PDBs also available!

[Andreas Boland @BolandLab_GE]

Today, we have released the first sub-3 Å EM-maps of the APC/C even before publication (PDB-7QE7)
We hope that this more complete and accurate model will already be useful for scientists working on cell cycle regulation.
Work led by Anna Höfler together with Jun Yu @JunYu_unige