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Together with my co-founders Michael @MichaelPoli6, Stefano @Massastrello and Armin @athmsx, I am excited to announce @RadicalNumerics is emerging from stealth with a $50M seed round to build general biological intelligence.
We’re also sharing an early preview of our new model Omnii, the most powerful genome language model to date.
Omnii preview link:
https://t.co/ouikMtRVwf
At Radical Numerics, our mission is to master the code of life, and to drive the frontier of biological AI for both design and defense.
This is our dual mandate, which comes from something our own team helped make possible.
Our founding team trained Evo and Evo 2, the largest biological AI models (40B params) trained on DNA sequences. Trillions of tokens across all of life, from microbes to mammals. It’s fully open source, and created the field now known as generative genomics.
Last year, scientists used Evo to generate the world’s first complete genome from scratch using AI. Turns out it was a bacteriophage—a type of virus. It functioned in the real world, and in this case it was harmless. But for us, it was a clear turning point.
It showed that AI is no longer just analyzing biology. It is on the cusp of generating functional lifeforms. Eventually, AI will have the power to design and control life itself.
That should make all of us incredibly excited, and incredibly uneasy. (Anyone can design DNA with a new function, and have it synthesized and delivered, like something from Amazon Prime).
The same technology that will help us cure cancer is the very technology that might create the next global pandemic, or worse, allow the creation of bioweapons that can wipe out populations.
We believe these forces are inseparable. If you work on the frontier of biology, you have to build technology to safeguard it from its misuse. Existing biosecurity tools are sorely losing the arms race, relying on outdated “have I seen this exact thing before?” style algorithms.
We founded Radical Numerics to turn the tide.
And we can’t do that by training on textbooks and natural language. We must understand the language of biology from the raw physical data itself, to reason across every molecule and modality, from DNA to proteins.
The next frontier for AI goes far beyond chatbots or video generators to models that can understand and engineer life.
Today, we’re previewing Omnii, which is already far surpassing Evo 2, and will continue improving as we scale and add new modalities (training now).
1. For human health, Omnii can read and write whole genomes (more on writing later). It’s state of the art (SOTA) on detecting causal variants for disease, and can rank Alzheimer's mutations zero-shot. We’re partnering with a diagnostics company to use Omnii for early cancer detection (pancreatic and multi-cancer).
2. For defense, Omnii is SOTA at detecting AI-generated pathogens. We benchmarked existing detection tools, and they simply can’t detect the AI-generated ones (“deepfake viruses”). We’re partnering with a US national lab to pilot Omnii for detecting the next pandemic, both natural and AI-generated.
We have a data center full of Blackwells in construction now to build the most powerful biological AI models ever. This mission takes a new kind of AI lab that can actually scale on physical, biological data: new alignment research (mid/post training), scaling long context, building out mech interp teams to dissect what these models learn, new architectures and systems designs, all from the ground up.
Our team is made up of AI researchers and scientists from top labs and institutions (e.g. Stanford, MIT, Google DeepMind), but more importantly, we all share the belief that this is the most important challenge of our lifetime. If you feel similarly, we are hiring. We aim to bring the brightest minds in AI and science together to save lives.
Thanks to our partners on this journey, led by Emergence Capital @emergencecap, with Obvious Ventures @obviousvc, Triatomic @TriatomicCap
, and Patrick Collison @patrickc. Our advisors include Eric Horvitz @erichorvitz, CSO of Microsoft, Chris Re @HazyResearch of Stanford, George Church @geochurch of Harvard, and Andrew Weber @AndyWeberNCB, former Assistant Secretary of Defense for Nuclear, Chemical and Biological Defense Programs.
Fortune article: https://t.co/L3f3f1329T
Jobs: https://t.co/EzsHSMcGJ1
This guy dressed up as Adolf Hitler during a live stream on PumpFun
He then sets the Israel flag on fire while saluting and rugs the coin for $50,000
This is exactly why crypto is dying
The Bull Season Cannot Be Stopped
🚨 2027 Crypto Outlook
#Bitcoin : $180K–$240K
#Ethereum : $9K–$14K
Thesis:
• Long-term uptrend remains intact above previous cycle highs.
• Global liquidity is likely to trend higher into 2027.
• Institutional participation continues to increase.
• ETF demand reduces available supply over time.
Until the macro structure breaks, I view major corrections as opportunities rather than trend reversals.
2027 will likely be remembered as another year of supply meeting demand. $BTC $ETH📈
🚨 WARNING: NEXT WEEK WILL BE THE WORST TIME OF 2026!!
When markets open on Monday, this won't be “just a dip.”
Stocks will dump.
Metals will dump.
Bitcoin will collapse.
If you hold any assets right now, you MUST be prepared for the biggest sell-off event of the year:
Insiders are nonstop dumping ALL assets right now.
They are not buying the dip.
They are moving into cash, reducing exposure, and preparing for a market crash.
And the warning signs are already appearing.
Bitcoin has already dumped below $60,000.
Stocks are falling.
Gold is falling.
Silver is falling.
This is not isolated weakness.
This is capital exiting risk across the board.
Capital freezes.
Confidence evaporates.
Global growth expectations reset lower instantly.
Meanwhile:
→ Japanese bond yields are surging
→ Foreign nations are dumping U.S. Treasuries
→ Global bonds are falling
→ Oil markets are becoming unstable
→ The dollar is losing stability
→ Liquidity is tightening worldwide
This is no longer one isolated problem.
This is systemic pressure building across MULTIPLE fronts simultaneously.
Inflation spikes globally.
Which means central banks will keep interest rates higher for longer.
And that creates the exact environment markets cannot survive in:
→ Slowing growth
→ Sticky inflation
→ Tight liquidity
→ Rising geopolitical risk
→ Collapsing investor confidence
Now connect the dots.
When geopolitical stress collides with a fragile financial system, reactions do not stay contained.
They COLLAPSE.
Capital does not rotate slowly.
It stampedes toward safety all at once.
And risk assets?
They do not dip.
They DUMP HARD.
This is exactly how chain reactions begin.
Once markets start pricing prolonged instability instead of temporary fear, the entire system changes.
Watch oil.
Watch bonds.
Watch interest rates.
Because once this accelerates, there will be no time left to react.
I have spent decades tracking macro and systemic market reactions like this.
When the next move becomes clear, I will share it here publicly.
Follow and turn notifications on.
Because by the time it reaches the headlines, it is already too late.
#ALTSEASON 2026 💸
🚨BULLISH #Memecoin and #Altcoin season has officially started getting ready for 50x 100x 1000x 🔥🚀
Which #Bnbchain project will start the next bull run?
Let's drop the Ticker
🔔 LIKE ~ FOLLOW 😎 ARE WE READY?
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All-time volume on NEAR Intents just crossed $20 billion.
This milestone is the result of a series of technical breakthroughs that removed some of the biggest constraints in cross-chain execution.
A deep dive on Intents' rapid momentum 🧵
everything is coming together for the greatest pump troll will ever see
the most viral meme in the world is sitting at 71m...
There aren't many memes like solana:5UUH9RTDiSpq6HKS6bp4NdU9PNJpXRXuiw6ShBTBhgH2
the team behind it is GRINDING, going viral on tiktok & owns the ip rights...
@blknoiz06 bought some memes & many other big names that haven't bought memes in a long time
on chain seems to be heating up FAST
buy. hold. patience. billions.
250+ companies trust Toku to run global payroll.
Now their teams can get paid in stablecoins across 100+ countries.
With Rain, they can spend it instantly at 175M merchant locations worldwide.
This is payroll now.