Bryan Bishop

mad science | bitcoin developer | aider+cursor maximalist

[Bryan Bishop @kanzure]

15 years of molecular nanotech, brain emulation, DNA synthesis, longevity, cryonics and more. Join the #hplusroadmap gc now available on discord https://t.co/pxxp6Ckv1g - work on cutting-edge technology development projects. Read more here: https://t.co/Sda1MyeNt0

[Bryan Bishop @kanzure]

@octal @DeryaTR_ https://t.co/Sgp6XpZkSu

[Crémieux @cremieuxrecueil]

This is hilarious.

Imagine a Hackathon where you're not actually allowed to do anything.

What's the point of a life sciences hackathon when you've banned inquiry into the life sciences?

[Bryan Bishop @kanzure]

gpt-5 is overly lobotomized on matters of biology. so many refusals. wow.

[Bryan Bishop @kanzure]

@octal @DeryaTR_ biologists are spared from the singularity https://t.co/NlwUojjouM

[Polymarket @Polymarket]

JUST IN: Biologists are growing frustrated as Anthropic’s “safe” Mythos-class model refuses to answer basic biology questions.

[Bryan Bishop @kanzure]

@simonmaechling I think you should change your strategy and instead of focusing on convincing people about things, you should just prove them wrong by directly building important things.

[Bryan Bishop @kanzure]

@chad_agn @Conza @L0RINC @bitcoincoreorg Because it didn't happen. Duh?

[Bryan Bishop @kanzure]

@NousResearch Convert from HTML to markdown before doing any token processing.

[Polymarket @Polymarket]

NEW: Study reveals 60% of Korean children & teens receiving growth hormone injections were "heightmaxxing," rather than treating a medical condition.

[Bryan Bishop @kanzure]

@zhaoweiasu Just fix them

[Matt Krisiloff @mattkrisiloff]

I’m so excited to share this update on @Conception –

We’ve generated the first early human eggs derived from stem cells.

This is a big deal -- the potential to redefine fertility is real.

[Bryan Bishop @kanzure]

@Conza @L0RINC @bitcoincoreorg My genetic engineering content has been on my websites for years.

[Bryan Bishop @kanzure]

@neuralamp4ever @Prof_Bryan_ @AgingBiology https://t.co/48WU5tCejT

[Max Berry @yashgaroth]

I did a writeup on Minicircle, the gene therapy startup injecting people with ~plasmids~

tl;dr: Minicircle is claiming obviously implausible numbers in plasmid capabilities and delivery efficiency: several orders of magnitude above the state of the art.

Link in the next tweet

[Bryan Bishop @kanzure]

@zetalyrae What you need is a neuroanatomy codex. A walkable map.

[Bryan Bishop @kanzure]

@iHooghvorst What biology needs is more courage. There's so much low hanging fruit.

[Bryan Bishop @kanzure]

@hsu_steve In person? Nah...

[Bryan Bishop @kanzure]

@DStrachman Doesn't sound like they have conviction. Skip high school and get back to me.

[Sumner L Norman @SumnerLN]

It’s been a big week (month? year? decade?) for ultrasound and I’m getting dozens of DMs so I’m going to do another one of these “the science behind” threads.

On this weeks’ edition: Aleph’s incredible images and the ultrasound science behind them. 🧵🔊

https://t.co/x870PNGq8r

[JM Rothberg @JMRothberg]

Wow $BFLY. Yesterday: full-body imaging @midjourney

Today: highest-resolution images ever of a living human brain through the skull @alephneuro !

Love seeing Butterfly Embedded™ partners take @ButterflyNetInc Ultrasound-on-Chip technology in completely novel directions

This is how platform technologies change the world

[Peter Todd @peterktodd]

gmaxwell's FCC submission re: mandating KYC for phones (comments close today!)

[Kording Lab 🦖 @KordingLab]

This is a 2h podcast of us talking about brains. How they work. What makes neuroscience hard. And how progress may look like.

[Bryan Bishop @kanzure]

@Empact polygenics bores me https://t.co/hcLmNT6hEy